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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1999 2
2000 4
2001 8
2002 12
2003 3
2004 3
2005 3
2006 4
2007 9
2008 4
2009 5
2010 7
2011 4
2012 3
2013 4
2014 12
2015 2
2016 3
2017 3
2018 6
2019 6
2020 7
2021 5
2022 3
2023 4
2024 2

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121 results

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Page 1
Acute promyelocytic leukemia current treatment algorithms.
Yilmaz M, Kantarjian H, Ravandi F. Yilmaz M, et al. Blood Cancer J. 2021 Jun 30;11(6):123. doi: 10.1038/s41408-021-00514-3. Blood Cancer J. 2021. PMID: 34193815 Free PMC article. Review.
In 1957, Hillestad et al. defined acute promyelocytic leukemia (APL) for the first time in the literature as a distinct type of acute myeloid leukemia (AML) with a "rapid downhill course" characterized with a severe bleeding tendency. ...The PML …
In 1957, Hillestad et al. defined acute promyelocytic leukemia (APL) for the first time in the literature as a d …
Differentiation syndrome in acute promyelocytic leukaemia.
Stahl M, Tallman MS. Stahl M, et al. Br J Haematol. 2019 Oct;187(2):157-162. doi: 10.1111/bjh.16151. Epub 2019 Aug 13. Br J Haematol. 2019. PMID: 31410848 Free article. Review.
Acute promyelocytic leukaemia differentiation syndrome (APL DS) is seen when patients with APL are treated with all-trans retinoic acid (ATRA) and/or arsenic trioxide (ATO). ...Immediate treatment with steroids at the first clinica …
Acute promyelocytic leukaemia differentiation syndrome (APL DS) is seen when patients with APL are treate …
Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet.
Sanz MA, Fenaux P, Tallman MS, Estey EH, Löwenberg B, Naoe T, Lengfelder E, Döhner H, Burnett AK, Chen SJ, Mathews V, Iland H, Rego E, Kantarjian H, Adès L, Avvisati G, Montesinos P, Platzbecker U, Ravandi F, Russell NH, Lo-Coco F. Sanz MA, et al. Blood. 2019 Apr 11;133(15):1630-1643. doi: 10.1182/blood-2019-01-894980. Epub 2019 Feb 25. Blood. 2019. PMID: 30803991 Free PMC article. Review.
Since the comprehensive recommendations for the management of acute promyelocytic leukemia (APL) reported in 2009, several studies have provided important insights, particularly regarding the role of arsenic trioxide (ATO) in frontline th …
Since the comprehensive recommendations for the management of acute promyelocytic leukemia (APL) reported in 200 …
Acute promyelocytic leukemia (APL): a review of the literature.
Jimenez JJ, Chale RS, Abad AC, Schally AV. Jimenez JJ, et al. Oncotarget. 2020 Mar 17;11(11):992-1003. doi: 10.18632/oncotarget.27513. eCollection 2020 Mar 17. Oncotarget. 2020. PMID: 32215187 Free PMC article. Review.
Acute Promyelocytic Leukemia (APL) is characterized by a block in differentiation where leukemic cells are halted at the promyelocyte stage. ...Furthermore, 20-25% of patients undergoing treatment will develop differentiation syndrome, a …
Acute Promyelocytic Leukemia (APL) is characterized by a block in differentiation where leukemic cells ar …
The treatment of acute promyelocytic leukemia in 2023: Paradigm, advances, and future directions.
Iyer SG, Elias L, Stanchina M, Watts J. Iyer SG, et al. Front Oncol. 2023 Jan 18;12:1062524. doi: 10.3389/fonc.2022.1062524. eCollection 2022. Front Oncol. 2023. PMID: 36741714 Free PMC article. Review.
The transformation of acute promyelocytic leukemia (APL) from an often fatal to highly curable cancer with long-term survival exceeding 90% is one of the greatest and most inspiring successes in oncology. ...In this review, we discuss the paradi …
The transformation of acute promyelocytic leukemia (APL) from an often fatal to highly curable cancer with long- …
RARA fusion genes in acute promyelocytic leukemia: a review.
De Braekeleer E, Douet-Guilbert N, De Braekeleer M. De Braekeleer E, et al. Expert Rev Hematol. 2014 Jun;7(3):347-57. doi: 10.1586/17474086.2014.903794. Epub 2014 Apr 10. Expert Rev Hematol. 2014. PMID: 24720386 Review.
The t(15;17)(q24;q21), generating a PML-RARA fusion gene, is the hallmark of acute promyelocytic leukemia (APL). At present, eight other genes fusing with RARA have been identified. ...RARA fusion proteins behave as potent transcriptional repressors of …
The t(15;17)(q24;q21), generating a PML-RARA fusion gene, is the hallmark of acute promyelocytic leukemia (APL). …
The success and the challenge of all-trans retinoic acid in the treatment of cancer.
Ni X, Hu G, Cai X. Ni X, et al. Crit Rev Food Sci Nutr. 2019;59(sup1):S71-S80. doi: 10.1080/10408398.2018.1509201. Epub 2018 Oct 2. Crit Rev Food Sci Nutr. 2019. PMID: 30277803 Review.
The great success of differentiation therapy with ATRA in acute promyelocytic leukemia (APL) not only improved the prognosis of APL but also spurred the studies of ATRA in the treatment of other tumors. Since the genetic and physiopatholo …
The great success of differentiation therapy with ATRA in acute promyelocytic leukemia (APL) not only imp …
Differentiation therapy revisited.
de Thé H. de Thé H. Nat Rev Cancer. 2018 Feb;18(2):117-127. doi: 10.1038/nrc.2017.103. Epub 2017 Dec 1. Nat Rev Cancer. 2018. PMID: 29192213 Review.
The concept of differentiation therapy emerged from the fact that hormones or cytokines may promote differentiation ex vivo, thereby irreversibly changing the phenotype of cancer cells. Its hallmark success has been the treatment of acute promyelocytic leu …
The concept of differentiation therapy emerged from the fact that hormones or cytokines may promote differentiation ex vivo, t …
Acute Promyelocytic Leukemia: A Summary.
Ryan MM. Ryan MM. J Adv Pract Oncol. 2018 Mar;9(2):178-187. Epub 2018 Mar 1. J Adv Pract Oncol. 2018. PMID: 30588352 Free PMC article. Review.
Acute promyelocytic leukemia is a distinct subtype of acute myeloid leukemia. ...Current therapy has advanced to include agents such as all-trans retinoic acid and arsenic trioxide, which have improved remission and survival rates. ...
Acute promyelocytic leukemia is a distinct subtype of acute myeloid leukemia. ...Current therapy has advanced to …
Evolving Chemotherapy Free Regimens for Acute Promyelocytic Leukemia.
Kulkarni U, Mathews V. Kulkarni U, et al. Front Oncol. 2021 Feb 25;11:621566. doi: 10.3389/fonc.2021.621566. eCollection 2021. Front Oncol. 2021. PMID: 33718181 Free PMC article. Review.
With the treatment advances over the last three decades, acute promyelocytic leukemia (APL) has evolved from being the most malignant form of acute leukemia to a leukemia with excellent long term survival rates. ...We have discussed the h …
With the treatment advances over the last three decades, acute promyelocytic leukemia (APL) has evolved from bei …
121 results