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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 8
1946 18
1947 15
1948 19
1949 11
1950 17
1951 22
1952 22
1953 16
1954 21
1955 26
1956 28
1957 28
1958 32
1959 24
1960 15
1961 28
1962 26
1963 50
1964 54
1965 30
1966 25
1967 34
1968 38
1969 63
1970 55
1971 49
1972 76
1973 65
1974 49
1975 62
1976 46
1977 34
1978 39
1979 41
1980 46
1981 38
1982 53
1983 44
1984 48
1985 57
1986 50
1987 61
1988 70
1989 71
1990 71
1991 93
1992 122
1993 98
1994 149
1995 161
1996 157
1997 206
1998 202
1999 212
2000 292
2001 271
2002 308
2003 311
2004 272
2005 296
2006 347
2007 332
2008 333
2009 336
2010 365
2011 340
2012 337
2013 313
2014 344
2015 348
2016 304
2017 312
2018 327
2019 320
2020 327
2021 284
2022 297
2023 236
2024 110

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The following terms were not found in PubMed: mannoketoheptose*, manno-2-heptulose*
Quoted phrases not found in phrase index: "Avocadofuran B", "Avocadofuran A"
Page 1
Phytosterols and Cardiovascular Disease.
Makhmudova U, Schulze PC, Lütjohann D, Weingärtner O. Makhmudova U, et al. Curr Atheroscler Rep. 2021 Sep 1;23(11):68. doi: 10.1007/s11883-021-00964-x. Curr Atheroscler Rep. 2021. PMID: 34468867 Free PMC article. Review.
PURPOSE OF REVIEW: Coronary heart disease is the leading cause of mortality worldwide. Elevated blood cholesterol levels are not only the major but also the best modifiable cardiovascular risk factor. ...
PURPOSE OF REVIEW: Coronary heart disease is the leading cause of mortality worldwide. Elevated blood cholesterol …
Phytosterols, Cholesterol Control, and Cardiovascular Disease.
Poli A, Marangoni F, Corsini A, Manzato E, Marrocco W, Martini D, Medea G, Visioli F. Poli A, et al. Nutrients. 2021 Aug 16;13(8):2810. doi: 10.3390/nu13082810. Nutrients. 2021. PMID: 34444970 Free PMC article. Review.
The use of phytosterols (or plant sterols) for the control of plasma cholesterol concentrations has recently gained traction because their efficacy is acknowledged by scientific authorities and leading guidelines. ...The panel concluded that the use of phytostero …
The use of phytosterols (or plant sterols) for the control of plasma cholesterol concentrations has recently gained traction b …
The cardiovascular benefits of dark chocolate.
Kerimi A, Williamson G. Kerimi A, et al. Vascul Pharmacol. 2015 Aug;71:11-5. doi: 10.1016/j.vph.2015.05.011. Epub 2015 May 27. Vascul Pharmacol. 2015. PMID: 26026398 Free article. Review.
Dark chocolate contains many biologically active components, such as catechins, procyanidins and theobromine from cocoa, together with added sucrose and lipids. All of these can directly or indirectly affect the cardiovascular system by multiple mechanisms. Intervention st …
Dark chocolate contains many biologically active components, such as catechins, procyanidins and theobromine from cocoa, together with added …
Plant Sterols and Plant Stanols in Cholesterol Management and Cardiovascular Prevention.
Barkas F, Bathrellou E, Nomikos T, Panagiotakos D, Liberopoulos E, Kontogianni MD. Barkas F, et al. Nutrients. 2023 Jun 22;15(13):2845. doi: 10.3390/nu15132845. Nutrients. 2023. PMID: 37447172 Free PMC article. Review.
Functional foods enriched with plant sterols/stanols have become the most widely used nonprescription cholesterol-lowering approach, despite the lack of randomized trials investigating their long-term safety and cardiovascular efficacy. The cholesterol-loweri …
Functional foods enriched with plant sterols/stanols have become the most widely used nonprescription cholesterol-lowering approach, …
Sitosterolemia.
Tada H, Kojima N, Takamura M, Kawashiri MA. Tada H, et al. Adv Clin Chem. 2022;110:145-169. doi: 10.1016/bs.acc.2022.06.006. Epub 2022 Aug 9. Adv Clin Chem. 2022. PMID: 36210074
Typical phenotypes of sitosterolemia, including elevated low-density lipoprotein (LDL) cholesterol, tendon xanthomas, and premature coronary artery disease, overlap those of homozygous FH; however, there are substantial differences between these two diseases …
Typical phenotypes of sitosterolemia, including elevated low-density lipoprotein (LDL) cholesterol, tendon xanthomas, and prem …
Diet and Cardiovascular Disease Risk Among Individuals with Familial Hypercholesterolemia: Systematic Review and Meta-Analysis.
Barkas F, Nomikos T, Liberopoulos E, Panagiotakos D. Barkas F, et al. Nutrients. 2020 Aug 13;12(8):2436. doi: 10.3390/nu12082436. Nutrients. 2020. PMID: 32823643 Free PMC article.
In comparison with cholesterol-lowering diet, the additional consumption of plant stanols decreased total cholesterol (MD: -0.62 mmol/L, 95% CI: -1.13 to -0.11, p = 0.02) and low-density lipoprotein cholesterol (MD: -0.58 mmol/L, 95% CI: -1.08 to -0.09 …
In comparison with cholesterol-lowering diet, the additional consumption of plant stanols decreased total cholesterol (MD: -0. …
Cardiovascular Effects of Flavonoids.
Sánchez M, Romero M, Gómez-Guzmán M, Tamargo J, Pérez-Vizcaino F, Duarte J. Sánchez M, et al. Curr Med Chem. 2019;26(39):6991-7034. doi: 10.2174/0929867326666181220094721. Curr Med Chem. 2019. PMID: 30569843 Review.
Cardiovascular Disease (CVD) is the major cause of death worldwide, especially in Western society. ...In recent years, the role of modulation of signaling pathways by direct interaction of flavonoids with multiple protein targets, namely kinases, has been increasingly reco …
Cardiovascular Disease (CVD) is the major cause of death worldwide, especially in Western society. ...In recent years, the role of mo …
Blood phytosterols in relation to cardiovascular diseases and mediating effects of blood lipids and hematological traits: a Mendelian randomization analysis.
Zhao Y, Zhuang Z, Li Y, Xiao W, Song Z, Huang N, Wang W, Dong X, Jia J, Huang T. Zhao Y, et al. Metabolism. 2023 Sep;146:155611. doi: 10.1016/j.metabol.2023.155611. Epub 2023 Jun 2. Metabolism. 2023. PMID: 37270173
BACKGROUND: Short-term clinical trials have shown the cholesterol-lowering potentials of phytosterols, but their impacts on cardiovascular disease (CVD) remain controversial. ...Notably, blood non-high-density lipoprotein cholesterol (nonHDL-C) …
BACKGROUND: Short-term clinical trials have shown the cholesterol-lowering potentials of phytosterols, but their impacts on …
Plant sterol enriched functional food and atherosclerosis.
Köhler J, Teupser D, Elsässer A, Weingärtner O. Köhler J, et al. Br J Pharmacol. 2017 Jun;174(11):1281-1289. doi: 10.1111/bph.13764. Epub 2017 Apr 5. Br J Pharmacol. 2017. PMID: 28253422 Free PMC article. Review.
Hypercholesterolaemia is a major cardiovascular risk factor. A healthy diet and a healthy lifestyle reduces cardiovascular risk. 'Functional foods' supplemented with phytosterols are recommended for the management of hypercholesterolaemia and have become a wi …
Hypercholesterolaemia is a major cardiovascular risk factor. A healthy diet and a healthy lifestyle reduces cardiovascular ris …
The Effects of Flavonoids in Cardiovascular Diseases.
Ciumărnean L, Milaciu MV, Runcan O, Vesa ȘC, Răchișan AL, Negrean V, Perné MG, Donca VI, Alexescu TG, Para I, Dogaru G. Ciumărnean L, et al. Molecules. 2020 Sep 21;25(18):4320. doi: 10.3390/molecules25184320. Molecules. 2020. PMID: 32967119 Free PMC article. Review.
Flavonoid research has been paid special attention to in recent times after the observation of their beneficial effects on the cardiovascular system. These favorable effects are exerted by flavonoids mainly due to their antioxidant properties, which result from the ability …
Flavonoid research has been paid special attention to in recent times after the observation of their beneficial effects on the cardiovasc …
9,935 results