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The following term was not found in PubMed: 7-decadien-1-ol
Page 1
Docosahexaenoic acid neurolipidomics.
Niemoller TD, Bazan NG. Niemoller TD, et al. Prostaglandins Other Lipid Mediat. 2010 Apr;91(3-4):85-9. doi: 10.1016/j.prostaglandins.2009.09.005. Epub 2009 Oct 3. Prostaglandins Other Lipid Mediat. 2010. PMID: 19804838 Free PMC article. Review.
It is well known that omega-3 fatty acids are beneficial for brain function. Docosahexaenoic acid [DHA; 4 22:6(n-3)] is the most abundant essential omega-3 fatty acid present in the brain and it has multiple mechanisms of exerting protective effects after cellular injury. …
It is well known that omega-3 fatty acids are beneficial for brain function. Docosahexaenoic acid [DHA; 4 22:6(n-3)] is the most abun …
Reevaluation of a Bicyclic Pyrazoline as a Selective 15-Lipoxygenase V-Type Activator Possessing Fatty Acid Specificity.
van Hoorebeke C, Yang K, Mussetter SJ, Koch G, Rutz N, Lokey RS, Crews P, Holman TR. van Hoorebeke C, et al. ACS Omega. 2022 Nov 17;7(47):43169-43179. doi: 10.1021/acsomega.2c05877. eCollection 2022 Nov 29. ACS Omega. 2022. PMID: 36467910 Free PMC article.
Steady-state kinetics demonstrate V-type activation for 1, with a beta value of 2.2 +/- 0.4 and an K (x) of 16 +/- 1 muM. Finally, it is demonstrated that the mechanism of activation for 1 is likely not due to decreasing substrate inhibition, as was postulated previously. …
Steady-state kinetics demonstrate V-type activation for 1, with a beta value of 2.2 +/- 0.4 and an K (x) of 16 +/- 1 muM. Finally, it …
A new quinolone alkaloid from the fruits of Tetradium ruticarpum.
Ma C, Liu X, Shan Y, Xu S, Feng X, Wang QZ. Ma C, et al. Nat Prod Res. 2021 Jan;35(2):222-227. doi: 10.1080/14786419.2019.1624954. Epub 2019 Jul 5. Nat Prod Res. 2021. PMID: 31273999
A rare new quinolone alkaloid containing three degrees of unsaturation in the side chain, named as 1-methyl-2-[(6Z,9Z,12Z)-6,9,12-pentadecatriene]-4(1H)-quinolone (1), together with three known quinolone alkaloids 1-methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quino …
A rare new quinolone alkaloid containing three degrees of unsaturation in the side chain, named as 1-methyl-2-[(6Z,9Z,12Z)-6,9,12-pentadecat …
Biochemical Characterization of 13-Lipoxygenases of Arabidopsis thaliana.
Maynard D, Chibani K, Schmidtpott S, Seidel T, Spross J, Viehhauser A, Dietz KJ. Maynard D, et al. Int J Mol Sci. 2021 Sep 23;22(19):10237. doi: 10.3390/ijms221910237. Int J Mol Sci. 2021. PMID: 34638573 Free PMC article.
This study aimed for characterizing the four annotated A. thaliana 13-LOX enzymes (LOX2, LOX3, LOX4, and LOX6) focusing on synthesis of 12-OPDA and 4Z,7Z,10Z)-12-[[-(1S,5S)-4-oxo-5-(2Z)-pent-2-en-1yl] cyclopent-2-en-1yl] dodeca-4,7,10-trienoic acid (OC …
This study aimed for characterizing the four annotated A. thaliana 13-LOX enzymes (LOX2, LOX3, LOX4, and LOX6) focusing on synthesis of 12-O …
Total Synthesis of Four Stereoisomers of (4Z,7Z,10Z,12E,16Z,18E)-14,20-Dihydroxy-4,7,10,12,16,18-docosahexaenoic Acid and Their Anti-inflammatory Activities.
Goto T, Urabe D, Masuda K, Isobe Y, Arita M, Inoue M. Goto T, et al. J Org Chem. 2015 Aug 7;80(15):7713-26. doi: 10.1021/acs.joc.5b01461. Epub 2015 Jul 24. J Org Chem. 2015. PMID: 26172872
A novel anti-inflammatory lipid mediator, (4Z,7Z,10Z,12E,14S,16Z,18E,20R)-14,20-dihydroxy-4,7,10,12,16,18-docosahexaenoic acid (1aa), and its three C14,C20 stereoisomers (1ab,ba,bb) were synthesized in a convergent fashion. ...
A novel anti-inflammatory lipid mediator, (4Z,7Z,10Z,12E,14S,16Z,18E,20R)-14,20-dihydroxy-4,7,10,12,16,18-docosahexaeno …
Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators.
Freedman C, Tran A, Tourdot BE, Kalyanaraman C, Perry S, Holinstat M, Jacobson MP, Holman TR. Freedman C, et al. Biochemistry. 2020 May 19;59(19):1832-1844. doi: 10.1021/acs.biochem.0c00233. Epub 2020 May 7. Biochemistry. 2020. PMID: 32324389 Free PMC article.
Human reticulocyte 15-lipoxygenase-1 (h15-LOX-1 or ALOX15) and platelet 12-lipoxygenase (h12-LOX or ALOX12) catalysis of docosahexaenoic acid (DHA) and the maresin precursor, 14S-hydroperoxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid (14S-HpDHA), were investigated t …
Human reticulocyte 15-lipoxygenase-1 (h15-LOX-1 or ALOX15) and platelet 12-lipoxygenase (h12-LOX or ALOX12) catalysis of docosahexaenoic aci …
Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages.
Dalli J, Vlasakov I, Riley IR, Rodriguez AR, Spur BW, Petasis NA, Chiang N, Serhan CN. Dalli J, et al. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12232-12237. doi: 10.1073/pnas.1607003113. Epub 2016 Oct 6. Proc Natl Acad Sci U S A. 2016. PMID: 27791009 Free PMC article.
With human recombinant enzymes, primary cells, and enantiomerically pure compounds we found that the synthetic maresin epoxide intermediate 13S,14S-eMaR (13S,14S-epoxy- 4Z,7Z,9E,11E,16Z,19Z-docosahexaenoic acid) was converted to MCTR1 (13R-glutathionyl, 14S-hydroxy- …
With human recombinant enzymes, primary cells, and enantiomerically pure compounds we found that the synthetic maresin epoxide intermediate …
66 results