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Year Number of Results
1985 1
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1995 4
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1998 6
1999 5
2000 3
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113 results

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Page 1
Developments in the Management of Growth Hormone Deficiency: Clinical Utility of Somapacitan.
Miller BS, Blair J, Horikawa R, Linglart A, Yuen KCJ. Miller BS, et al. Drug Des Devel Ther. 2024 Feb 3;18:291-306. doi: 10.2147/DDDT.S315172. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 38333899 Free PMC article. Review.
Additionally, the administration of somapacitan and timing of measurement of serum insulin-like growth factor-I (IGF-I) levels are summarized. Information on administration, advice on missed doses, and clinical guidelines are discussed, a …
Additionally, the administration of somapacitan and timing of measurement of serum insulin-like growth factor …
Oral Octreotide: A Review of Recent Clinical Trials and Practical Recommendations for Its Use in the Treatment of Patients With Acromegaly.
Yuen KCJ, Samson SL. Yuen KCJ, et al. Endocr Pract. 2022 Jun;28(6):637-645. doi: 10.1016/j.eprac.2022.04.009. Epub 2022 Apr 19. Endocr Pract. 2022. PMID: 35452815 Review.
OBJECTIVE: Acromegaly is characterized by chronic growth hormone (GH) and insulin-like growth factor 1 (IGF-1) hypersecretion, often caused by a GH-secreting pituitary adenoma. ...RESULTS: In 4 pivotal clinical trials involving 238 patients with …
OBJECTIVE: Acromegaly is characterized by chronic growth hormone (GH) and insulin-like growth factor 1 (I …
The Effects of 5 Years of Growth Hormone Treatment on Growth and Body Composition in Patients with Temple Syndrome.
Juriaans AF, Trueba-Timmermans DJ, Kerkhof GF, Grootjen LN, Walet S, Sas TCJ, Rotteveel J, Zwaveling-Soonawala N, Verrijn Stuart AA, Hokken-Koelega ACS. Juriaans AF, et al. Horm Res Paediatr. 2023;96(5):483-494. doi: 10.1159/000530420. Epub 2023 Mar 28. Horm Res Paediatr. 2023. PMID: 36977395
RESULTS: In the entire group, mean (95% CI) height SDS increased significantly during 5 years of GH treatment from -1.78 (-2.52; -1.04) to 0.11 (-0.66; 0.87). Fat mass percentage SDS decreased significantly during the first year of GH, and lean body mass (LBM) SDS and LBM …
RESULTS: In the entire group, mean (95% CI) height SDS increased significantly during 5 years of GH treatment from -1.78 (-2.52; -1.04) to 0 …
Clinical characteristics and management of growth hormone excess in patients with McCune-Albright syndrome.
Yao Y, Liu Y, Wang L, Deng K, Yang H, Lu L, Feng F, Xing B, You H, Jin Z, Wang R, Pan H, Chen S, Zhu H. Yao Y, et al. Eur J Endocrinol. 2017 Mar;176(3):295-303. doi: 10.1530/EJE-16-0715. Epub 2016 Dec 22. Eur J Endocrinol. 2017. PMID: 28007843
DESIGN: Retrospective clinical study. METHODS: Clinical data from 52 MAS patients were analyzed. Serum GH and IGF1 levels, as well as nadir GH levels after an oral glucose tolerance test and alkaline phosphatase (ALP) levels were determined before and after the treatment. …
DESIGN: Retrospective clinical study. METHODS: Clinical data from 52 MAS patients were analyzed. Serum GH and IGF1 levels, as well as …
Effect of risperidone treatment on insulin-like growth factor-1 and interleukin-17 in drug naive first-episode schizophrenia.
Chen D, Li H, Zhao Q, Song J, Lin C, Yu J. Chen D, et al. Psychiatry Res. 2021 Mar;297:113717. doi: 10.1016/j.psychres.2021.113717. Epub 2021 Jan 11. Psychiatry Res. 2021. PMID: 33503523
After treatment, IGF-1 levels in patients decreased significantly, whereas the IL-17 serum levels had no significant change compared to their baseline concentration. ...Results suggested that the inflammatory system is activated and serum IGF-1 may contribute …
After treatment, IGF-1 levels in patients decreased significantly, whereas the IL-17 serum levels had no significant change co …
Effect of hypothyroidism and its treatment on the IGF system in infants and children.
Purandare A, Co Ng L, Godil M, Ahnn SH, Wilson TA. Purandare A, et al. J Pediatr Endocrinol Metab. 2003 Jan;16(1):35-42. doi: 10.1515/jpem.2003.16.1.35. J Pediatr Endocrinol Metab. 2003. PMID: 12585338 Review.
Baseline IGFBP-2 levels did not differ from the control values in both these groups but decreased significantly after correction of the hypothyroidism. Although these changes appeared to occur with thyroxine therapy, multiple regression analysis suggested that age w …
Baseline IGFBP-2 levels did not differ from the control values in both these groups but decreased significantly after correction of t …
Pegvisomant treatment in patients with acromegaly in clinical practice: The French ACROSTUDY.
Chanson P, Brue T, Delemer B, Caron P, Borson-Chazot F, Zouater H; Médecins de l'Étude ACROSTUDY. Chanson P, et al. Ann Endocrinol (Paris). 2015 Dec;76(6):664-70. doi: 10.1016/j.ando.2015.10.003. Epub 2015 Nov 17. Ann Endocrinol (Paris). 2015. PMID: 26596374
The most prescribed initial dose of pegvisomant (after possible administration of a loading dose) was 10mg/day and, starting from the 2nd year, the median dose was 20mg/day. Serum IGF-1 concentration decreased as soon as pegvisomant was started and after 5 years the …
The most prescribed initial dose of pegvisomant (after possible administration of a loading dose) was 10mg/day and, starting from the 2nd ye …
Voice Characteristics in Patients with Acromegaly during Treatment.
Wolters TLC, Roerink SHPP, Drenthen LCA, Wagenmakers MAEM, van den Broek GB, Rutten KIM, Herruer JM, Hermus ARMM, Netea-Maier RT. Wolters TLC, et al. J Voice. 2021 Nov;35(6):932.e13-932.e27. doi: 10.1016/j.jvoice.2020.01.006. Epub 2020 Jan 28. J Voice. 2021. PMID: 32005626

The within-subject change in serum IGF-1 levels (97.3 (40.6-208) to 22.4 (10.2-34.1) nmol/L (P < 0.001)) during follow-up correlated positively with the changes in VHI questionnaire scores (R 0.32-0.45; P = 0.002-0.03). CONCLUSIONS: At diagnosis and during acromegaly tr

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The within-subject change in serum IGF-1 levels (97.3 (40.6-208) to 22.4 (10.2-34.1) nmol/L (P < 0.001)) during follow-up correlat

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Pharmacological management of acromegaly: a current perspective.
Manjila S, Wu OC, Khan FR, Khan MM, Arafah BM, Selman WR. Manjila S, et al. Neurosurg Focus. 2010 Oct;29(4):E14. doi: 10.3171/2010.7.FOCUS10168. Neurosurg Focus. 2010. PMID: 20887124 Review.
Acromegaly is a chronic disorder of enhanced growth hormone (GH) secretion and elevated insulin-like growth factor-I (IGF-I) levels, the most frequent cause of which is a pituitary adenoma. ...Selective GH receptor antagonists, such as pegvisoma …
Acromegaly is a chronic disorder of enhanced growth hormone (GH) secretion and elevated insulin-like growth factor …
Insulin-like growth factor binding protein (IGFBP) displacers: relevance to the treatment of renal disease.
Roelfsema V, Lane MH, Clark RG. Roelfsema V, et al. Pediatr Nephrol. 2000 Jul;14(7):584-8. doi: 10.1007/s004670000350. Pediatr Nephrol. 2000. PMID: 10912523 Review.
In the rat this molecule activated the IGF system and produced IGF-like effects in vivo, such as increased kidney size, reduced serum creatinine, increased bone growth and increased body weight. Novel synthetic peptides have also been discovered which bind to specific IGFB …
In the rat this molecule activated the IGF system and produced IGF-like effects in vivo, such as increased kidney size, reduced serum …
113 results