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Diagnosis and management of testosterone deficiency.
McBride JA, Carson CC, Coward RM. McBride JA, et al. Asian J Androl. 2015 Mar-Apr;17(2):177-86. doi: 10.4103/1008-682X.143317. Asian J Androl. 2015. PMID: 25532575 Free PMC article. Review.
Testosterone supplementation therapy (TST) use has dramatically increased over the past decade, due to the availability of newer agents, aggressive marketing, and an increasing incidence of testosterone deficiency (TD). ...
Testosterone supplementation therapy (TST) use has dramatically increased over the past decade, due to the availability of newer agen …
Functional hypogonadism in middle-aged and older men: testosterone treatment or not?
Grossmann M, Jones TH. Grossmann M, et al. Eur J Endocrinol. 2021 Aug 3;185(3):D1-D9. doi: 10.1530/EJE-21-0362. Eur J Endocrinol. 2021. PMID: 34260411 Review.
Clinicians commonly encounter middle-aged and older men who present with functional hypogonadism, that is, with clinical features compatible with androgen deficiency and lowered serum testosterone, but without evidence of organic hypothalamic-pituitary-testicular axis pathology. …
Clinicians commonly encounter middle-aged and older men who present with functional hypogonadism, that is, with clinical features compatible …
Effects of treatment for diabetes mellitus on testosterone concentrations: A systematic review.
Van Cauwenberghe J, De Block C, Vanderschueren D, Antonio L. Van Cauwenberghe J, et al. Andrology. 2023 Feb;11(2):225-233. doi: 10.1111/andr.13318. Epub 2022 Nov 11. Andrology. 2023. PMID: 36251281 Free article. Review.
Currently available treatment options (testosterone replacement therapy or lifestyle changes) hold possible risks or are insufficient. ...
Currently available treatment options (testosterone replacement therapy or lifestyle changes) hold possible risks or are insufficient …
Advances in the treatment of functional male hypogonadism.
Corona G, Rastrelli G, Sparano C, Vignozzi L, Sforza A, Maggi M. Corona G, et al. Expert Rev Endocrinol Metab. 2024 Mar;19(2):163-177. doi: 10.1080/17446651.2023.2296022. Epub 2023 Dec 20. Expert Rev Endocrinol Metab. 2024. PMID: 38117229 Review.
INTRODUCTION: Functional hypogonadism is frequently found in obese men, particularly those with metabolic complications. Several possible therapeutic approaches could be considered. AREAS COVERED: An extensive search on Medline, Embase, and Cochrane databases was performed …
INTRODUCTION: Functional hypogonadism is frequently found in obese men, particularly those with metabolic complications. Several possible …
Risks of Serious Injury with Testosterone Treatment.
Yarnell CJ, Thiruchelvam D, Redelmeier DA. Yarnell CJ, et al. Am J Med. 2021 Jan;134(1):84-94.e6. doi: 10.1016/j.amjmed.2020.07.037. Epub 2020 Sep 12. Am J Med. 2021. PMID: 32926849
The primary outcome was defined as an acute traumatic event that required emergency medical care. RESULTS: A total of 64,386 patients were treated with testosterone of whom 89% were men with a median age of 52 years. ...CONCLUSIONS: Testosterone treatment was associated wi …
The primary outcome was defined as an acute traumatic event that required emergency medical care. RESULTS: A total of 64,386 patients …
Enclomiphene citrate for the treatment of secondary male hypogonadism.
Rodriguez KM, Pastuszak AW, Lipshultz LI. Rodriguez KM, et al. Expert Opin Pharmacother. 2016 Aug;17(11):1561-7. doi: 10.1080/14656566.2016.1204294. Epub 2016 Jul 4. Expert Opin Pharmacother. 2016. PMID: 27337642 Free PMC article. Review.
The ability to treat testosterone deficiency in men while maintaining fertility supports a role for enclomiphene citrate in the treatment of men in whom testosterone therapy is not a suitable option....
The ability to treat testosterone deficiency in men while maintaining fertility supports a role for enclomiphene citrate in the treatment of …
Experiences and treatment patterns of hypogonadal men in a U.S. health system.
Shortridge EF, Polzer P, Donga P, Blanchette CM, Fang Y, Burudpakdee C, Carswell B. Shortridge EF, et al. Int J Clin Pract. 2014 Oct;68(10):1257-63. doi: 10.1111/ijcp.12418. Epub 2014 Mar 28. Int J Clin Pract. 2014. PMID: 24673748
OBJECTIVE: To examine self-reported experiences with hypogonadism (HG) and patterns of testosterone replacement therapy (TRT) in men seeking care in a U.S. healthcare system. METHODS: Men 18 years old with HG were identified from the 2008-2010 Reliant electronic med …
OBJECTIVE: To examine self-reported experiences with hypogonadism (HG) and patterns of testosterone replacement therapy (TRT) in men …
The effect of testosterone treatment on prostate histology and apoptosis in men with late-onset hypogonadism.
Efesoy O, Apa D, Tek M, Çayan S. Efesoy O, et al. Aging Male. 2016 Jun;19(2):79-84. doi: 10.3109/13685538.2016.1148131. Epub 2016 Feb 29. Aging Male. 2016. PMID: 26927833
OBJECTIVES: To investigate the effect of testosterone replacement therapy (TRT) on prostate histology and apoptosis in men with late-onset hypogonadism (LOH). ...Prostate biopsy was repeated at the end of 1 year of testosterone therapy. In addition to clinical and b …
OBJECTIVES: To investigate the effect of testosterone replacement therapy (TRT) on prostate histology and apoptosis in men with late- …
24 results