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Table representation of search results timeline featuring number of search results per year.

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1994 1
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2002 1
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2010 4
2011 6
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2014 5
2015 5
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53 results

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Page 1
The Differential Diagnosis and Treatment of Atypical Parkinsonism.
Levin J, Kurz A, Arzberger T, Giese A, Höglinger GU. Levin J, et al. Dtsch Arztebl Int. 2016 Feb 5;113(5):61-9. doi: 10.3238/arztebl.2016.0061. Dtsch Arztebl Int. 2016. PMID: 26900156 Free PMC article. Review.
In DLB, synuclein is mainly deposited in neocortical neurons, with some brain stem involvement as well. The main clinical features are dementia and, later on, parkinsonism. In MSA, synuclein is deposited in oligodendrocytes, mainly in the cerebellum but also in the brai
In DLB, synuclein is mainly deposited in neocortical neurons, with some brain stem involvement as well. The main clinical features ar …
Brain Sagging Dementia-Diagnosis, Treatment, and Outcome: A Review.
Lashkarivand A, Eide PK. Lashkarivand A, et al. Neurology. 2022 May 10;98(19):798-805. doi: 10.1212/WNL.0000000000200511. Epub 2022 Mar 25. Neurology. 2022. PMID: 35338080 Review.
Brain sagging dementia (BSD), caused by spontaneous intracranial hypotension (SIH), is a rare syndrome that is only recently recognized, mimicking the clinical findings of behavioral variant frontotemporal dementia (bvFTD). ...Headache is present in the majority of
Brain sagging dementia (BSD), caused by spontaneous intracranial hypotension (SIH), is a rare syndrome that is only recently recogniz
Genotype-phenotype correlation in the spectrum of frontotemporal dementia-parkinsonian syndromes and advanced diagnostic approaches.
Zecca C, Tortelli R, Carrera P, Dell'Abate MT, Logroscino G, Ferrari M. Zecca C, et al. Crit Rev Clin Lab Sci. 2023 May;60(3):171-188. doi: 10.1080/10408363.2022.2150833. Epub 2022 Dec 12. Crit Rev Clin Lab Sci. 2023. PMID: 36510705 Review.
The term frontotemporal dementia (FTD) refers to a group of progressive neurodegenerative disorders characterized mainly by atrophy of the frontal and anterior temporal lobes. Based on clinical presentation, three main clinical syndromes have traditionally been desc …
The term frontotemporal dementia (FTD) refers to a group of progressive neurodegenerative disorders characterized mainly by atroph
Diagnostic accuracy of research criteria for prodromal frontotemporal dementia.
Benussi A, Premi E, Grassi M, Alberici A, Cantoni V, Gazzina S, Archetti S, Gasparotti R, Fumagalli GG, Bouzigues A, Russell LL, Samra K, Cash DM, Bocchetta M, Todd EG, Convery RS, Swift I, Sogorb-Esteve A, Heller C, van Swieten JC, Jiskoot LC, Seelaar H, Sanchez-Valle R, Moreno F, Laforce RJ, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, Mendonça A, Tiraboschi P, Butler CR, Santana I, Gerhard A, Le Ber I, Pasquier F, Ducharme S, Levin J, Sorbi S, Otto M, Padovani A, Rohrer JD, Borroni B; Genetic Frontotemporal dementia Initiative (GENFI). Benussi A, et al. Alzheimers Res Ther. 2024 Jan 12;16(1):10. doi: 10.1186/s13195-024-01383-1. Alzheimers Res Ther. 2024. PMID: 38216961 Free PMC article.
BACKGROUND: The Genetic Frontotemporal Initiative Staging Group has proposed clinical criteria for the diagnosis of prodromal frontotemporal dementia (FTD), termed mild cognitive and/or behavioral and/or motor impairment (MCBMI). ...A subgroup of patients underwent …
BACKGROUND: The Genetic Frontotemporal Initiative Staging Group has proposed clinical criteria for the diagnosis of prodromal fron
Neuropsychological assessment and differential diagnosis in young-onset dementias.
Sitek EJ, Barczak A, Harciarek M. Sitek EJ, et al. Psychiatr Clin North Am. 2015 Jun;38(2):265-79. doi: 10.1016/j.psc.2015.01.003. Epub 2015 Mar 7. Psychiatr Clin North Am. 2015. PMID: 25998115 Review.
Although Alzheimer's disease is the most common cause of dementia in the elderly, there are several conditions (ie, frontotemporal dementia or Huntington's disease) associated with a relatively earlier onset. ...
Although Alzheimer's disease is the most common cause of dementia in the elderly, there are several conditions (ie, frontotemporal de …
Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management.
Rabinovici GD, Miller BL. Rabinovici GD, et al. CNS Drugs. 2010 May;24(5):375-98. doi: 10.2165/11533100-000000000-00000. CNS Drugs. 2010. PMID: 20369906 Free PMC article. Review.
Three distinct clinical variants of FTLD have been described: (i) behavioural-variant frontotemporal dementia, characterized by changes in behaviour and personality in association with frontal-predominant cortical degeneration; (ii) semantic dementia, a syndrome of progres …
Three distinct clinical variants of FTLD have been described: (i) behavioural-variant frontotemporal dementia, characterized by chang …
Extra-motor cerebral changes and manifestations in primary lateral sclerosis.
Finegan E, Shing SLH, Chipika RH, Chang KM, McKenna MC, Doherty MA, Hengeveld JC, Vajda A, Pender N, Donaghy C, Hutchinson S, McLaughlin RL, Hardiman O, Bede P. Finegan E, et al. Brain Imaging Behav. 2021 Oct;15(5):2283-2296. doi: 10.1007/s11682-020-00421-4. Epub 2021 Jan 7. Brain Imaging Behav. 2021. PMID: 33409820
Primary lateral sclerosis (PLS) is classically considered a 'pure' upper motor neuron disorder. Motor cortex atrophy and pyramidal tract degeneration are thought to be pathognomonic of PLS, but extra-motor cerebral changes are poorly characterized. ...Clinical asses …
Primary lateral sclerosis (PLS) is classically considered a 'pure' upper motor neuron disorder. Motor cortex atrophy and pyramidal tr …
Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease.
Chitramuthu BP, Bennett HPJ, Bateman A. Chitramuthu BP, et al. Brain. 2017 Dec 1;140(12):3081-3104. doi: 10.1093/brain/awx198. Brain. 2017. PMID: 29053785 Review.
Haploinsufficiency caused by autosomal dominant mutations within the GRN gene leads to frontotemporal lobar degeneration, a progressive neuronal atrophy that presents in patients as frontotemporal dementia. Frontotemporal dementia is an early onset for …
Haploinsufficiency caused by autosomal dominant mutations within the GRN gene leads to frontotemporal lobar degeneration, a progressi …
The Role of Neuropsychiatric Symptoms in Research Diagnostic Criteria for Neurodegenerative Diseases.
Cummings J. Cummings J. Am J Geriatr Psychiatry. 2021 Apr;29(4):375-383. doi: 10.1016/j.jagp.2020.07.011. Epub 2020 Jul 27. Am J Geriatr Psychiatry. 2021. PMID: 32819825 Free PMC article. Review.
Diagnostic criteria were reviewed including those for dementia, Alzheimer's disease, mild cognitive impairment, mild behavioral impairment, prodromal Alzheimer's disease, dementia with Lewy bodies, prodromal dementia with Lewy bodies, Parkinson's disease, multiple system atrop
Diagnostic criteria were reviewed including those for dementia, Alzheimer's disease, mild cognitive impairment, mild behavioral impairment, …
Repurposing Vorinostat for the Treatment of Disorders Affecting Brain.
Athira KV, Sadanandan P, Chakravarty S. Athira KV, et al. Neuromolecular Med. 2021 Dec;23(4):449-465. doi: 10.1007/s12017-021-08660-4. Epub 2021 May 4. Neuromolecular Med. 2021. PMID: 33948878 Review.
Based on the findings in recent years, we summarize the therapeutic potential of vorinostat (VOR), the first approved histone deacetylase (HDAC) inhibitor, in disorders of brain, and strategies to improve drug efficacy and reduce side effects. Scientific evidences p …
Based on the findings in recent years, we summarize the therapeutic potential of vorinostat (VOR), the first approved histone deacety …
53 results