Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1985 1
1993 2
1997 1
1998 1
2002 1
2003 1
2004 4
2005 4
2007 5
2008 2
2009 3
2010 1
2011 3
2012 3
2013 4
2014 5
2015 7
2016 7
2017 4
2018 1
2019 6
2020 11
2021 11
2022 12
2023 6
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

94 results

Results by year

Filters applied: . Clear all
Page 1
Congenital Hyperinsulinism: Diagnosis and Treatment Update.
Demirbilek H, Hussain K. Demirbilek H, et al. J Clin Res Pediatr Endocrinol. 2017 Dec 30;9(Suppl 2):69-87. doi: 10.4274/jcrpe.2017.S007. Epub 2017 Dec 27. J Clin Res Pediatr Endocrinol. 2017. PMID: 29280746 Free PMC article. Review.
Advances in molecular genetics, imaging techniques (18F-DOPA positron emission tomography/computed tomography scanning), medical therapy and surgical advances (laparoscopic and open pancreatectomy) have changed the management and improved the outcome of patients with HH. T …
Advances in molecular genetics, imaging techniques (18F-DOPA positron emission tomography/computed tomography scanning), medical therapy …
Neonatal hypoglycemia: lack of evidence for a safe management.
Roeper M, Hoermann H, Kummer S, Meissner T. Roeper M, et al. Front Endocrinol (Lausanne). 2023 Jun 8;14:1179102. doi: 10.3389/fendo.2023.1179102. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37361517 Free PMC article. Review.
These research gaps need to be addressed in future studies, systematically comparing different management strategies to progressively optimize the balance between prevention of neurodevelopmental sequelae and the burden of diagnostic or therapeutic procedures. Unfortunatel …
These research gaps need to be addressed in future studies, systematically comparing different management strategies to progressively optimi …
Congenital hyperinsulinism: recent updates on molecular mechanisms, diagnosis and management.
Giri D, Hawton K, Senniappan S. Giri D, et al. J Pediatr Endocrinol Metab. 2021 Sep 21;35(3):279-296. doi: 10.1515/jpem-2021-0369. Print 2022 Mar 28. J Pediatr Endocrinol Metab. 2021. PMID: 34547194 Review.
Congenital hyperinsulinism (CHI) is a rare disease characterized by an unregulated insulin release, leading to hypoglycaemia. ...This review article provides an overview of the background, clinical presentation, diagnosis, molecular genetics and therapy for c …
Congenital hyperinsulinism (CHI) is a rare disease characterized by an unregulated insulin release, leading to hypoglycaemia. …
Hyperinsulinemic hypoglycemia in children and adolescents: Recent advances in understanding of pathophysiology and management.
Gϋemes M, Rahman SA, Kapoor RR, Flanagan S, Houghton JAL, Misra S, Oliver N, Dattani MT, Shah P. Gϋemes M, et al. Rev Endocr Metab Disord. 2020 Dec;21(4):577-597. doi: 10.1007/s11154-020-09548-7. Rev Endocr Metab Disord. 2020. PMID: 32185602 Free PMC article. Review.
It is the most common cause of persistent and recurrent hypoglycemia in the neonatal period. HH may be primary, Congenital HH (CHH), when it is associated with variants in a number of genes implicated in pancreatic development and function. ...Potential future developments …
It is the most common cause of persistent and recurrent hypoglycemia in the neonatal period. HH may be primary, Congenital HH (CHH), …
Management and Appropriate Use of Diazoxide in Infants and Children with Hyperinsulinism.
Brar PC, Heksch R, Cossen K, De Leon DD, Kamboj MK, Marks SD, Marshall BA, Miller R, Page L, Stanley T, Mitchell D, Thornton P. Brar PC, et al. J Clin Endocrinol Metab. 2020 Dec 1;105(12):dgaa543. doi: 10.1210/clinem/dgaa543. J Clin Endocrinol Metab. 2020. PMID: 32810255
Diazoxide is the only Food and Drug Agency-approved pharmacologic treatment for neonatal hypoglycemia caused by hyperinsulinism (HI). Recent publications have highlighted that diazoxide has serious adverse effects (AEs) such as pulmonary hypertension (2-3%) and neutropenia …
Diazoxide is the only Food and Drug Agency-approved pharmacologic treatment for neonatal hypoglycemia caused by hyperinsulinism (HI). …
Genotype and phenotype correlations in 417 children with congenital hyperinsulinism.
Snider KE, Becker S, Boyajian L, Shyng SL, MacMullen C, Hughes N, Ganapathy K, Bhatti T, Stanley CA, Ganguly A. Snider KE, et al. J Clin Endocrinol Metab. 2013 Feb;98(2):E355-63. doi: 10.1210/jc.2012-2169. Epub 2012 Dec 28. J Clin Endocrinol Metab. 2013. PMID: 23275527 Free PMC article.
CONTEXT: Hypoglycemia due to congenital hyperinsulinism (HI) is caused by mutations in 9 genes. OBJECTIVE: Our objective was to correlate genotype with phenotype in 417 children with HI. ...Accurate and timely prediction of phenotype based on genotype is critical to …
CONTEXT: Hypoglycemia due to congenital hyperinsulinism (HI) is caused by mutations in 9 genes. OBJECTIVE: Our objective was t …
Diagnosis and management of hyperinsulinaemic hypoglycaemia.
Galcheva S, Al-Khawaga S, Hussain K. Galcheva S, et al. Best Pract Res Clin Endocrinol Metab. 2018 Aug;32(4):551-573. doi: 10.1016/j.beem.2018.05.014. Epub 2018 Jun 6. Best Pract Res Clin Endocrinol Metab. 2018. PMID: 30086874 Review.
Histologically, congenital HH can be divided into 3 types: diffuse, focal and atypical. ...Recent advances in the field of HH include new rapid molecular genetic testing, novel imaging methods (18F-DOPA PET/CT), novel medical therapy (long-acting octreotide formulat …
Histologically, congenital HH can be divided into 3 types: diffuse, focal and atypical. ...Recent advances in the field of HH include …
Glutamate dehydrogenase hyperinsulinism: mechanisms, diagnosis, and treatment.
Zeng Q, Sang YM. Zeng Q, et al. Orphanet J Rare Dis. 2023 Jan 31;18(1):21. doi: 10.1186/s13023-023-02624-6. Orphanet J Rare Dis. 2023. PMID: 36721237 Free PMC article. Review.
Congenital hyperinsulinism (CHI) is a genetically heterogeneous disease, in which intractable, persistent hypoglycemia is induced by excessive insulin secretion and increased serum insulin concentration. To date,15 genes have been found to be associated with the pat …
Congenital hyperinsulinism (CHI) is a genetically heterogeneous disease, in which intractable, persistent hypoglycemia is indu …
Novel Preparations of Glucagon for the Prevention and Treatment of Hypoglycemia.
Hawkes CP, De Leon DD, Rickels MR. Hawkes CP, et al. Curr Diab Rep. 2019 Sep 6;19(10):97. doi: 10.1007/s11892-019-1216-4. Curr Diab Rep. 2019. PMID: 31493043 Free PMC article. Review.
PURPOSE OF REVIEW: New more stable formulations of glucagon have recently become available, and these provide an opportunity to expand the clinical roles of this hormone in the prevention and management of insulin-induced hypoglycemia. This is applicable in type 1 diabetes, hy …
PURPOSE OF REVIEW: New more stable formulations of glucagon have recently become available, and these provide an opportunity to expand the c …
94 results