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Page 1
Management of patients susceptible to malignant hyperthermia: A surgeon's perspective.
Carlson KJ, Sun SA, Swan C, Koenig M, Derkay CS. Carlson KJ, et al. Int J Pediatr Otorhinolaryngol. 2022 Aug;159:111187. doi: 10.1016/j.ijporl.2022.111187. Epub 2022 May 30. Int J Pediatr Otorhinolaryngol. 2022. PMID: 35660936
OBJECTIVES: Malignant hyperthermia (MH) susceptibility caries broad implications for the care of pediatric surgical patients. ...An inappropriate label of "MH-susceptible" may result in decreased access to care and treatment delays....
OBJECTIVES: Malignant hyperthermia (MH) susceptibility caries broad implications for the care of pediatric surgi …
European Malignant Hyperthermia Group guidelines for investigation of malignant hyperthermia susceptibility.
Hopkins PM, Rüffert H, Snoeck MM, Girard T, Glahn KP, Ellis FR, Müller CR, Urwyler A; European Malignant Hyperthermia Group. Hopkins PM, et al. Br J Anaesth. 2015 Oct;115(4):531-9. doi: 10.1093/bja/aev225. Epub 2015 Jul 18. Br J Anaesth. 2015. PMID: 26188342 Free article.
It is 30 yr since the British Journal of Anaesthesia published the first consensus protocol for the laboratory diagnosis of malignant hyperthermia susceptibility from the European Malignant Hyperthermia Group. ...In 2001, our group also publishe …
It is 30 yr since the British Journal of Anaesthesia published the first consensus protocol for the laboratory diagnosis of malignant …
Consensus Statement of the Malignant Hyperthermia Association of the United States on Unresolved Clinical Questions Concerning the Management of Patients With Malignant Hyperthermia.
Litman RS, Smith VI, Larach MG, Mayes L, Shukry M, Theroux MC, Watt S, Wong CA. Litman RS, et al. Anesth Analg. 2019 Apr;128(4):652-659. doi: 10.1213/ANE.0000000000004039. Anesth Analg. 2019. PMID: 30768455
At a recent consensus conference, the Malignant Hyperthermia Association of the United States addressed 6 important and unresolved clinical questions concerning the optimal management of patients with malignant hyperthermia (MH) susceptibility o …
At a recent consensus conference, the Malignant Hyperthermia Association of the United States addressed 6 important and unreso …
Hyperthermic treatment of cutaneous malignancies.
Draelos ZK, Levine N. Draelos ZK, et al. J Am Acad Dermatol. 1983 Oct;9(4):623-8. doi: 10.1016/s0190-9622(83)70175-1. J Am Acad Dermatol. 1983. PMID: 6355221 Review.
Malignant cells are susceptible to high temperatures, and recent technical advances have allowed heat to be concentrated at the site of the neoplasm in vivo. ...Animal studies show high cure rates for squamous cell carcinoma with the use of radiofrequency hyperth …
Malignant cells are susceptible to high temperatures, and recent technical advances have allowed heat to be concentrated at th …
A case of discordance between genotype and phenotype in a malignant hyperthermia family.
Fortunato G, Carsana A, Tinto N, Brancadoro V, Canfora G, Salvatore F. Fortunato G, et al. Eur J Hum Genet. 1999 May-Jun;7(4):415-20. doi: 10.1038/sj.ejhg.5200314. Eur J Hum Genet. 1999. PMID: 10352931
Malignant hyperthermia (MH) is an inherited autosomal dominant pharmacogenetic disorder and is the major cause of anaesthesia-induced death. Malignant hyperthermia susceptibility is usually diagnosed by the in vitro contracture test (IVCT) perfo …
Malignant hyperthermia (MH) is an inherited autosomal dominant pharmacogenetic disorder and is the major cause of anaesthesia- …
Malignant hyperthermia in North America: genetic screening of the three hot spots in the type I ryanodine receptor gene.
Sei Y, Sambuughin NN, Davis EJ, Sachs D, Cuenca PB, Brandom BW, Tautz T, Rosenberg H, Nelson TE, Muldoon SM. Sei Y, et al. Anesthesiology. 2004 Oct;101(4):824-30. doi: 10.1097/00000542-200410000-00005. Anesthesiology. 2004. PMID: 15448513 Free article.
BACKGROUND: Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle, manifested as a life-threatening hypermetabolic crisis after exposure to anesthetics. Type I ryanodine receptor 1 is the primary gene responsible for susceptibility to M …
BACKGROUND: Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle, manifested as a life-threatening hyp …
Erythrocyte fragility screening is not a tool for diagnosis of human malignant hyperthermia.
Kistler P, Fletcher JE, Rosenberg H. Kistler P, et al. Anesth Analg. 1987 Oct;66(10):1004-7. Anesth Analg. 1987. PMID: 3631560
The fragility of erythrocytes from 21 patients undergoing in vitro skeletal muscle contracture testing for malignant hyperthermia (MH) susceptibility was examined. Osmotic fragility was determined by the degree of hemolysis in buffered saline solutions of dec …
The fragility of erythrocytes from 21 patients undergoing in vitro skeletal muscle contracture testing for malignant hyperthermia …
A comparison of the caffeine halothane muscle contracture test with the molecular genetic diagnosis of malignant hyperthermia.
MacKenzie AE, Allen G, Lahey D, Crossan ML, Nolan K, Mettler G, Worton RG, MacLennan DH, Korneluk R. MacKenzie AE, et al. Anesthesiology. 1991 Jul;75(1):4-8. doi: 10.1097/00000542-199107000-00002. Anesthesiology. 1991. PMID: 2064058 Free article.
Malignant hyperthermia (MH) is currently diagnosed by the caffeine-halothane contracture (CHC) test. In a previous study, this test was used to establish linkage between the human gene for MH susceptibility and the ryanodine receptor (RYR) gene. The current s …
Malignant hyperthermia (MH) is currently diagnosed by the caffeine-halothane contracture (CHC) test. In a previous study, this …
Recent advances in the diagnosis of malignant hyperthermia susceptibility: how confident can we be of genetic testing?
Robinson RL, Anetseder MJ, Brancadoro V, van Broekhoven C, Carsana A, Censier K, Fortunato G, Girard T, Heytens L, Hopkins PM, Jurkat-Rott K, Klinger W, Kozak-Ribbens G, Krivosic R, Monnier N, Nivoche Y, Olthoff D, Rueffert H, Sorrentino V, Tegazzin V, Mueller CR. Robinson RL, et al. Eur J Hum Genet. 2003 Apr;11(4):342-8. doi: 10.1038/sj.ejhg.5200964. Eur J Hum Genet. 2003. PMID: 12700608
Malignant hyperthermia (MH) is a condition that manifests in susceptible individuals only on exposure to certain anaesthetic agents. ...Discordance observed in some families between IVCT phenotype and susceptibility locus genotype could limit the confi …
Malignant hyperthermia (MH) is a condition that manifests in susceptible individuals only on exposure to certain anaest …
Increased sensitivity to 4-chloro-m-cresol and caffeine in primary myotubes from malignant hyperthermia susceptible individuals carrying the ryanodine receptor 1 Thr2206Met (C6617T) mutation.
Wehner M, Rueffert H, Koenig F, Neuhaus J, Olthoff D. Wehner M, et al. Clin Genet. 2002 Aug;62(2):135-46. doi: 10.1034/j.1399-0004.2002.620206.x. Clin Genet. 2002. PMID: 12220451
Malignant hyperthermia (MH) is an autosomal-dominant disorder of skeletal muscle, triggered by volatile anaesthetics and depolarizing muscle relaxants. ...The intracellular calcium concentration in response to 4-chloro-m-cresol and to caffeine was investigate …
Malignant hyperthermia (MH) is an autosomal-dominant disorder of skeletal muscle, triggered by volatile anaesthetics and depol …
12 results