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Molecular diagnostics as a tool to personalize treatment in adult glioma patients.
Jeuken JW, van der Maazen RW, Wesseling P. Jeuken JW, et al. Technol Cancer Res Treat. 2006 Jun;5(3):215-29. doi: 10.1177/153303460600500305. Technol Cancer Res Treat. 2006. PMID: 16700618 Free article. Review.
Gliomas, the most frequent primary brain tumors in humans, form a heterogeneous group, encompassing many different histological types and malignancy grades. ...Finally, future perspectives will be presented with regard to the contribution of molecular diagnostics to tailor …
Gliomas, the most frequent primary brain tumors in humans, form a heterogeneous group, encompassing many different histological types …
Phenotype versus genotype in gliomas displaying inter- or intratumoral histological heterogeneity.
Walker C, du Plessis DG, Joyce KA, Machell Y, Thomson-Hehir J, Al Haddad SA, Broome JC, Warnke PC. Walker C, et al. Clin Cancer Res. 2003 Oct 15;9(13):4841-51. Clin Cancer Res. 2003. PMID: 14581356
RESULTS: Loss of 1p36 and 19q13 was seen only in oligodendroglial histology in 7 of 13 oligodendrogliomas. 17p13 loss was found in 14 of 41 tumors in astrocytic, oligoastrocytic, oligodendroglial, and glioblastomatous histologies. Chromosome 10 loss was seen in all …
RESULTS: Loss of 1p36 and 19q13 was seen only in oligodendroglial histology in 7 of 13 oligodendrogliomas. 17p13 loss was found in 14 of 41 …