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Genetic testing in dyslipidemia: A scientific statement from the National Lipid Association.
Brown EE, Sturm AC, Cuchel M, Braun LT, Duell PB, Underberg JA, Jacobson TA, Hegele RA. Brown EE, et al. J Clin Lipidol. 2020 Jul-Aug;14(4):398-413. doi: 10.1016/j.jacl.2020.04.011. Epub 2020 May 7. J Clin Lipidol. 2020. PMID: 32507592
The genetic basis for more than 2 dozen monogenic dyslipidemias has largely been defined. Genetic technologies, such as DNA sequencing, can detect both rare and common DNA variants underlying dyslipidemias, and these methods are increasingly available. ...Potential benefit …
The genetic basis for more than 2 dozen monogenic dyslipidemias has largely been defined. Genetic technologies, such as DNA sequencin …
Surgical management of dyslipidemia: clinical and experimental evidence.
Moghadasian MH, Frohlich JJ, Saleem M, Hong JM, Qayumi K, Scudamore CH. Moghadasian MH, et al. J Invest Surg. 2001 Mar-Apr;14(2):71-8. doi: 10.1080/08941930152024183. J Invest Surg. 2001. PMID: 11396622 Review.
PIB surgery is one of the most effective methods for reduction of plasma cholesterol levels, particularly in patients with heterozygous familial hypercholesterolemia. This procedure is also applicable to treatment of sitosterolemia, a rare genetic disorder in which the abs …
PIB surgery is one of the most effective methods for reduction of plasma cholesterol levels, particularly in patients with heterozygous fami …
Discovery of the hepatic canalicular and intestinal cholesterol transporters. New targets for treatment of hypercholesterolemia.
Zanlungo S, Nervi F. Zanlungo S, et al. Eur Rev Med Pharmacol Sci. 2003 Mar-Apr;7(2):33-9. Eur Rev Med Pharmacol Sci. 2003. PMID: 12911117 Review.
Interestingly, mutation of ABCG5 and or ABCG8 genes in man causes sitosterolemia, a rare genetic disease characterized by massive absorption of plant sterols and premature arteriosclerosis. The potential pharmacological manipulation of biliary cholesterol secretion represe …
Interestingly, mutation of ABCG5 and or ABCG8 genes in man causes sitosterolemia, a rare genetic disease characterized by massive abs …