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Page 1
Thalamic gliomas in adults: a systematic review of clinical characteristics, treatment strategies, and survival outcomes.
Palmisciano P, El Ahmadieh TY, Haider AS, Bin Alamer O, Robertson FC, Plitt AR, Aoun SG, Yu K, Cohen-Gadol A, Moss NS, Patel TR, Sawaya R. Palmisciano P, et al. J Neurooncol. 2021 Dec;155(3):215-224. doi: 10.1007/s11060-021-03898-1. Epub 2021 Nov 19. J Neurooncol. 2021. PMID: 34797525 Review.
PURPOSE: Thalamic gliomas are rare neoplasms that pose significant surgical challenges. ...The median progression-free survival was 9 months, and the overall two-year survival rate was 19.7%. The two-year survival rates of low-grade and high-grade
PURPOSE: Thalamic gliomas are rare neoplasms that pose significant surgical challenges. ...The median progression-free surviva …
Management and outcome of low-grade astrocytomas of the midline in children: a retrospective review.
Hoffman HJ, Soloniuk DS, Humphreys RP, Drake JM, Becker LE, De Lima BO, Piatt JH Jr. Hoffman HJ, et al. Neurosurgery. 1993 Dec;33(6):964-71. doi: 10.1227/00006123-199312000-00002. Neurosurgery. 1993. PMID: 8134009 Review.
Low-grade astrocytomas of the midline of the brain can be difficult to manage because of their location. ...Eighty-eight children with biopsy-proven low-grade astrocytomas were identified. Forty-three tumors occurred in the optic pathways or hypothalam
Low-grade astrocytomas of the midline of the brain can be difficult to manage because of their location. ...Eighty-eight child
Surgical and molecular considerations in the treatment of pediatric thalamopeduncular tumors.
Lee RP, Foster KA, Lillard JC, Klimo P Jr, Ellison DW, Orr B, Boop FA. Lee RP, et al. J Neurosurg Pediatr. 2017 Sep;20(3):247-255. doi: 10.3171/2017.4.PEDS16668. Epub 2017 Jul 7. J Neurosurg Pediatr. 2017. PMID: 28686121 Free PMC article.
OBJECTIVE Thalamopeduncular tumors are a group of pediatric low-grade gliomas that arise at the interface of the thalamus and brainstem peduncle. ...Molecular status may correlate with clinical features, and the presence of BRAF lesions offers an addit …
OBJECTIVE Thalamopeduncular tumors are a group of pediatric low-grade gliomas that arise at the interface of the tha
Diagnostic challenges, management and outcomes of midline low-grade gliomas.
Waqar M, Hanif S, Rathi N, Das K, Zakaria R, Brodbelt AR, Walker C, Jenkinson MD. Waqar M, et al. J Neurooncol. 2014 Nov;120(2):389-98. doi: 10.1007/s11060-014-1563-6. Epub 2014 Aug 6. J Neurooncol. 2014. PMID: 25096797
INTRODUCTION: Low-grade gliomas (LGGs) are slow-growing and diffusely infiltrating tumours constituting 25-30 % of adult gliomas. ...METHODS: Midline LGGs were identified from a retrospective database of adult patients who received a histological diagn …
INTRODUCTION: Low-grade gliomas (LGGs) are slow-growing and diffusely infiltrating tumours constituting 25-30 % of adul …
Single-agent bevacizumab in the treatment of recurrent or refractory pediatric low-grade glioma: A single institutional experience.
Gorsi HS, Khanna PC, Tumblin M, Yeh-Nayre L, Milburn M, Elster JD, Crawford JR. Gorsi HS, et al. Pediatr Blood Cancer. 2018 Sep;65(9):e27234. doi: 10.1002/pbc.27234. Epub 2018 May 11. Pediatr Blood Cancer. 2018. PMID: 29750399
INTRODUCTION: Bevacizumab-based therapy has been demonstrated to be effective in the treatment of refractory or recurrent pediatric low-grade glioma (LGG); however its efficacy as a single agent is less understood. ...CONCLUSION: Single-agent bevacizum …
INTRODUCTION: Bevacizumab-based therapy has been demonstrated to be effective in the treatment of refractory or recurrent pediatric …
Current management of low-grade astrocytomas of childhood.
Sutton LN. Sutton LN. Pediatr Neurosci. 1987;13(2):98-107. doi: 10.1159/000120311. Pediatr Neurosci. 1987. PMID: 3325954 Review.
Current management strategies consist of surgery, radiation therapy, chemotherapy and immunotherapy, although the optimal treatment is yet to be defined. ...
Current management strategies consist of surgery, radiation therapy, chemotherapy and immunotherapy, although the optimal treatment i …
Conservative management of presumed low-grade gliomas in the asymptomatic pediatric population.
Ali ZS, Lang SS, Sutton LN. Ali ZS, et al. World Neurosurg. 2014 Feb;81(2):368-73. doi: 10.1016/j.wneu.2013.01.038. Epub 2013 Jan 12. World Neurosurg. 2014. PMID: 23321383
OBJECTIVE: The optimal management of asymptomatic children with small, nonenhancing intracranial lesions presumed to be low-grade gliomas (LGGs) is not entirely clear in the literature. ...The most common diagnosis based on clinical and radiographic features …
OBJECTIVE: The optimal management of asymptomatic children with small, nonenhancing intracranial lesions presumed to be low-grade
Surgical treatment of thalamic tumors in children.
Cinalli G, Aguirre DT, Mirone G, Ruggiero C, Cascone D, Quaglietta L, Aliberti F, Santi SD, Buonocore MC, Nastro A, Spennato P. Cinalli G, et al. J Neurosurg Pediatr. 2018 Mar;21(3):247-257. doi: 10.3171/2017.7.PEDS16463. Epub 2017 Dec 22. J Neurosurg Pediatr. 2018. PMID: 29271729
At the end of the surgical phase, of 25 patients, 15 (60%) achieved a gross-total resection, 4 (16%) achieved a subtotal resection, and 6 (24%) achieved a partial resection. Eighteen patients harbored low-grade tumors in our series. In this group, the mean follow-up …
At the end of the surgical phase, of 25 patients, 15 (60%) achieved a gross-total resection, 4 (16%) achieved a subtotal resection, and 6 (2 …
Nimotuzumab therapy in the treatment of pediatric central nervous system tumors: single-center experience.
Susam-Sen H, Varan A, Bajin İ, Göçmen R, Aydın B, Yalcin B, Kurucu N, Kutluk T, Bayhan T, Akyuz C. Susam-Sen H, et al. Naunyn Schmiedebergs Arch Pharmacol. 2021 Aug;394(8):1769-1777. doi: 10.1007/s00210-021-02109-y. Epub 2021 Jun 21. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 34151393
The study included nine patients with the diffuse intrinsic pontine glioma; eight with medulloblastoma; three each with anaplastic ependymoma, glioblastoma multiforme, and central nervous system primitive neuroectodermal tumor (CNS PNET); two patients with gliomatosis cere …
The study included nine patients with the diffuse intrinsic pontine glioma; eight with medulloblastoma; three each with anaplastic ep …
Visual improvement despite radiologically stable disease after treatment with carboplatin in children with progressive low-grade optic/thalamic gliomas.
Mitchell AE, Elder JE, Mackey DA, Waters KD, Ashley DM. Mitchell AE, et al. J Pediatr Hematol Oncol. 2001 Dec;23(9):572-7. doi: 10.1097/00043426-200112000-00004. J Pediatr Hematol Oncol. 2001. PMID: 11902299 Review.
BACKGROUND: The purpose of this study was to examine the clinical and radiologic response to carboplatin by children with progressive optic/thalamic gliomas. PATIENTS AND METHODS: Between July 1997 and July 1999, 12 consecutive children were treated with monthly car …
BACKGROUND: The purpose of this study was to examine the clinical and radiologic response to carboplatin by children with progressive optic/ …
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