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Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
J Biol Chem. 2013 Feb 22;288(8):5914-26. doi: 10.1074/jbc.M112.442103. Epub 2013 Jan 4.
J Biol Chem. 2013.
PMID: 23293020
Free PMC article.
Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex.
Sokolow S, Luu SH, Nandy K, Miller CA, Vinters HV, Poon WW, Gylys KH.
Sokolow S, et al.
Neurobiol Dis. 2012 Jan;45(1):381-7. doi: 10.1016/j.nbd.2011.08.027. Epub 2011 Sep 3.
Neurobiol Dis. 2012.
PMID: 21914482
Free PMC article.
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AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly.
Sokolow S, Henkins KM, Bilousova T, Miller CA, Vinters HV, Poon W, Cole GM, Gylys KH.
Sokolow S, et al.
Neurobiol Aging. 2012 Aug;33(8):1545-55. doi: 10.1016/j.neurobiolaging.2011.05.011. Epub 2011 Jul 7.
Neurobiol Aging. 2012.
PMID: 21741125
Free PMC article.
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High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease.
Sokolow S, Luu SH, Headley AJ, Hanson AY, Kim T, Miller CA, Vinters HV, Gylys KH.
Sokolow S, et al.
Cell Calcium. 2011 Apr;49(4):208-16. doi: 10.1016/j.ceca.2010.12.008. Epub 2011 Mar 5.
Cell Calcium. 2011.
PMID: 21382638
Free PMC article.
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Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes.
Fein JA, Sokolow S, Miller CA, Vinters HV, Yang F, Cole GM, Gylys KH.
Fein JA, et al.
Am J Pathol. 2008 Jun;172(6):1683-92. doi: 10.2353/ajpath.2008.070829. Epub 2008 May 8.
Am J Pathol. 2008.
PMID: 18467692
Free PMC article.
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