075615/Z/04/z/WT_/Wellcome Trust/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2011	5
2012	5
2013	6
2014	2
2015	1
2021	2
2024	0

1

β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins.

Ninkina N, Millership SJ, Peters OM, Connor-Robson N, Chaprov K, Kopylov AT, Montoya A, Kramer H, Withers DJ, Buchman VL. Ninkina N, et al. J Biol Chem. 2021 Dec;297(6):101375. doi: 10.1016/j.jbc.2021.101375. Epub 2021 Nov 2. J Biol Chem. 2021. PMID: 34736896 Free PMC article.

2

Triple-Knockout, Synuclein-Free Mice Display Compromised Lipid Pattern.

Guschina IA, Ninkina N, Roman A, Pokrovskiy MV, Buchman VL. Guschina IA, et al. Molecules. 2021 May 21;26(11):3078. doi: 10.3390/molecules26113078. Molecules. 2021. PMID: 34064018 Free PMC article.

3

A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression.

Ninkina N, Connor-Robson N, Ustyugov AA, Tarasova TV, Shelkovnikova TA, Buchman VL. Ninkina N, et al. Sci Rep. 2015 Nov 13;5:16615. doi: 10.1038/srep16615. Sci Rep. 2015. PMID: 26564109 Free PMC article.

4

Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms.

Shelkovnikova TA, Robinson HK, Southcombe JA, Ninkina N, Buchman VL. Shelkovnikova TA, et al. Hum Mol Genet. 2014 Oct 1;23(19):5211-26. doi: 10.1093/hmg/ddu243. Epub 2014 May 19. Hum Mol Genet. 2014. PMID: 24842888 Free PMC article.

5

Compromised paraspeckle formation as a pathogenic factor in FUSopathies.

Shelkovnikova TA, Robinson HK, Troakes C, Ninkina N, Buchman VL. Shelkovnikova TA, et al. Hum Mol Genet. 2014 May 1;23(9):2298-312. doi: 10.1093/hmg/ddt622. Epub 2013 Dec 11. Hum Mol Genet. 2014. PMID: 24334610 Free PMC article.

6

C9ORF72 transcription in a frontotemporal dementia case with two expanded alleles.

Cooper-Knock J, Higginbottom A, Connor-Robson N, Bayatti N, Bury JJ, Kirby J, Ninkina N, Buchman VL, Shaw PJ. Cooper-Knock J, et al. Neurology. 2013 Nov 5;81(19):1719-21. doi: 10.1212/01.wnl.0000435295.41974.2e. Epub 2013 Oct 9. Neurology. 2013. PMID: 24107864 Free PMC article.

7

Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm.

Shelkovnikova TA, Robinson HK, Connor-Robson N, Buchman VL. Shelkovnikova TA, et al. Cell Cycle. 2013 Oct 1;12(19):3194-202. doi: 10.4161/cc.26241. Epub 2013 Sep 4. Cell Cycle. 2013. PMID: 24013423 Free PMC article.

8

Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice.

Shelkovnikova TA, Peters OM, Deykin AV, Connor-Robson N, Robinson H, Ustyugov AA, Bachurin SO, Ermolkevich TG, Goldman IL, Sadchikova ER, Kovrazhkina EA, Skvortsova VI, Ling SC, Da Cruz S, Parone PA, Buchman VL, Ninkina NN. Shelkovnikova TA, et al. J Biol Chem. 2013 Aug 30;288(35):25266-25274. doi: 10.1074/jbc.M113.492017. Epub 2013 Jul 18. J Biol Chem. 2013. PMID: 23867462 Free PMC article.

9

Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.

Jones AR, Woollacott I, Shatunov A, Cooper-Knock J, Buchman V, Sproviero W, Smith B, Scott KM, Balendra R, Abel O, McGuffin P, Ellis CM, Shaw PJ, Morrison KE, Farmer A, Lewis CM, Leigh PN, Shaw CE, Powell JF, Al-Chalabi A. Jones AR, et al. Neurobiol Aging. 2013 Sep;34(9):2234.e1-7. doi: 10.1016/j.neurobiolaging.2013.03.003. Epub 2013 Apr 12. Neurobiol Aging. 2013. PMID: 23587638 Free PMC article.

10

Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation.

Buchman VL, Cooper-Knock J, Connor-Robson N, Higginbottom A, Kirby J, Razinskaya OD, Ninkina N, Shaw PJ. Buchman VL, et al. Mol Neurodegener. 2013 Apr 8;8:12. doi: 10.1186/1750-1326-8-12. Mol Neurodegener. 2013. PMID: 23566336 Free PMC article.

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