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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 3
1981 13
1982 9
1983 11
1984 6
1985 7
1986 8
1987 6
1988 3
1989 3
1990 7
1991 8
1992 8
1993 6
1994 10
1995 15
1996 8
1997 14
1998 11
1999 25
2000 21
2001 30
2002 29
2003 26
2004 24
2005 26
2006 20
2007 37
2008 47
2009 48
2010 71
2011 68
2012 59
2013 70
2014 66
2015 72
2016 65
2017 43
2018 50
2019 46
2020 41
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1,041 results
Results by year
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Page 1
Interferon-stimulated genes and their antiviral effector functions.
Schoggins JW, Rice CM. Schoggins JW, et al. Curr Opin Virol. 2011 Dec;1(6):519-25. doi: 10.1016/j.coviro.2011.10.008. Curr Opin Virol. 2011. PMID: 22328912 Free PMC article. Review.
Elucidating Mechanisms of Drug-Resistant Plasmodium falciparum.
Ross LS, Fidock DA. Ross LS, et al. Cell Host Microbe. 2019 Jul 10;26(1):35-47. doi: 10.1016/j.chom.2019.06.001. Cell Host Microbe. 2019. PMID: 31295423 Free PMC article. Review.
Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis.
Mishra BB, Lovewell RR, Olive AJ, Zhang G, Wang W, Eugenin E, Smith CM, Phuah JY, Long JE, Dubuke ML, Palace SG, Goguen JD, Baker RE, Nambi S, Mishra R, Booty MG, Baer CE, Shaffer SA, Dartois V, McCormick BA, Chen X, Sassetti CM. Mishra BB, et al. Nat Microbiol. 2017 May 15;2:17072. doi: 10.1038/nmicrobiol.2017.72. Nat Microbiol. 2017. PMID: 28504669 Free PMC article.
In contrast, we report that nitric oxide primarily protects mice by repressing an interleukin-1- and 12/15-lipoxygenase-dependent neutrophil recruitment cascade that promotes bacterial replication. ...
In contrast, we report that nitric oxide primarily protects mice by repressing an interleukin-1- and 12/15-lipoxygenase-dependent neu …
Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane.
Frieman M, Yount B, Heise M, Kopecky-Bromberg SA, Palese P, Baric RS. Frieman M, et al. J Virol. 2007 Sep;81(18):9812-24. doi: 10.1128/JVI.01012-07. Epub 2007 Jun 27. J Virol. 2007. PMID: 17596301 Free PMC article.
Using severe acute respiratory syndrome coronavirus (SARS-CoV) as a model, we demonstrate that SARS-COV ORF6 protein is localized to the endoplasmic reticulum (ER)/Golgi membrane in infected cells, where it binds to and disrupts nuclear import complex formation by tethering karyo …
Using severe acute respiratory syndrome coronavirus (SARS-CoV) as a model, we demonstrate that SARS-COV ORF6 protein is localized to the end …
Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming.
Kwakkenbos MJ, Diehl SA, Yasuda E, Bakker AQ, van Geelen CM, Lukens MV, van Bleek GM, Widjojoatmodjo MN, Bogers WM, Mei H, Radbruch A, Scheeren FA, Spits H, Beaumont T. Kwakkenbos MJ, et al. Nat Med. 2010 Jan;16(1):123-8. doi: 10.1038/nm.2071. Epub 2009 Dec 20. Nat Med. 2010. PMID: 20023635 Free PMC article.
Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells.
Rashidian M, Ingram JR, Dougan M, Dongre A, Whang KA, LeGall C, Cragnolini JJ, Bierie B, Gostissa M, Gorman J, Grotenbreg GM, Bhan A, Weinberg RA, Ploegh HL. Rashidian M, et al. J Exp Med. 2017 Aug 7;214(8):2243-2255. doi: 10.1084/jem.20161950. Epub 2017 Jun 30. J Exp Med. 2017. PMID: 28666979 Free PMC article.
Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non-small cell lung cancer in a subset of patients. ...
Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non-small cell lung …
Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery.
Buss JA, Baidin V, Welsh MA, Flores-Kim J, Cho H, Wood BM, Uehara T, Walker S, Kahne D, Bernhardt TG. Buss JA, et al. Antimicrob Agents Chemother. 2018 Dec 21;63(1):e01530-18. doi: 10.1128/AAC.01530-18. Print 2019 Jan. Antimicrob Agents Chemother. 2018. PMID: 30323039 Free PMC article.
A screen of690,000 compounds identified 1,300 compounds that were active against E. coli Pathway-directed screening of a majority of this subset of compounds for Rod inhibitors successfully identified eight analogs of the MreB antagonist A22. ...
A screen of690,000 compounds identified 1,300 compounds that were active against E. coli Pathway-directed screening of a majority of …
A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis.
Manjunatha UH, Vinayak S, Zambriski JA, Chao AT, Sy T, Noble CG, Bonamy GMC, Kondreddi RR, Zou B, Gedeck P, Brooks CF, Herbert GT, Sateriale A, Tandel J, Noh S, Lakshminarayana SB, Lim SH, Goodman LB, Bodenreider C, Feng G, Zhang L, Blasco F, Wagner J, Leong FJ, Striepen B, Diagana TT. Manjunatha UH, et al. Nature. 2017 Jun 15;546(7658):376-380. doi: 10.1038/nature22337. Epub 2017 May 31. Nature. 2017. PMID: 28562588 Free PMC article.
Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation.
Zhu X, Messer JS, Wang Y, Lin F, Cham CM, Chang J, Billiar TR, Lotze MT, Boone DL, Chang EB. Zhu X, et al. J Clin Invest. 2015 Mar 2;125(3):1098-110. doi: 10.1172/JCI76344. Epub 2015 Feb 2. J Clin Invest. 2015. PMID: 25642769 Free PMC article.
Here, we demonstrated that cytosolic HMGB1 regulates apoptosis by protecting the autophagy proteins beclin 1 and ATG5 from calpain-mediated cleavage during inflammation. ...In vitro cleavage assays and studies of enteroids verified that HMGB1 protects beclin 1 and A …
Here, we demonstrated that cytosolic HMGB1 regulates apoptosis by protecting the autophagy proteins beclin 1 and ATG5 from calpain-me …
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC. Wu B, et al. Science. 2010 Nov 19;330(6007):1066-71. doi: 10.1126/science.1194396. Epub 2010 Oct 7. Science. 2010. PMID: 20929726 Free PMC article.
The G protein-coupled chemokine receptor CXCR4 is specifically implicated in cancer metastasis and HIV-1 infection. Here we report five independent crystal structures of CXCR4 bound to an antagonist small molecule IT1t and a cyclic peptide CVX15 at 2.5 to 3.2 angstrom reso …
The G protein-coupled chemokine receptor CXCR4 is specifically implicated in cancer metastasis and HIV-1 infection. Here we report fi …
1,041 results
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