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Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.
Thein SL, Menzel S, Peng X, Best S, Jiang J, Close J, Silver N, Gerovasilli A, Ping C, Yamaguchi M, Wahlberg K, Ulug P, Spector TD, Garner C, Matsuda F, Farrall M, Lathrop M. Thein SL, et al. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11346-51. doi: 10.1073/pnas.0611393104. Epub 2007 Jun 25. Proc Natl Acad Sci U S A. 2007. PMID: 17592125 Free PMC article.