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Year | Number of Results |
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2011 | 2 |
2012 | 1 |
2013 | 1 |
2014 | 2 |
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Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers.
Biochim Biophys Acta. 2012 Mar;1823(3):742-55. doi: 10.1016/j.bbamcr.2011.10.008. Epub 2011 Oct 29.
Biochim Biophys Acta. 2012.
PMID: 22062686
Free PMC article.
Review.
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90.
Moulick K, Ahn JH, Zong H, Rodina A, Cerchietti L, Gomes DaGama EM, Caldas-Lopes E, Beebe K, Perna F, Hatzi K, Vu LP, Zhao X, Zatorska D, Taldone T, Smith-Jones P, Alpaugh M, Gross SS, Pillarsetty N, Ku T, Lewis JS, Larson SM, Levine R, Erdjument-Bromage H, Guzman ML, Nimer SD, Melnick A, Neckers L, Chiosis G.
Moulick K, et al.
Nat Chem Biol. 2011 Sep 25;7(11):818-26. doi: 10.1038/nchembio.670.
Nat Chem Biol. 2011.
PMID: 21946277
Free PMC article.
Item in Clipboard
Experimental and structural testing module to analyze paralogue-specificity and affinity in the Hsp90 inhibitors series.
Taldone T, Patel PD, Patel M, Patel HJ, Evans CE, Rodina A, Ochiana S, Shah SK, Uddin M, Gewirth D, Chiosis G.
Taldone T, et al.
J Med Chem. 2013 Sep 12;56(17):6803-18. doi: 10.1021/jm400619b. Epub 2013 Aug 21.
J Med Chem. 2013.
PMID: 23965125
Free PMC article.
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Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70.
Taldone T, Kang Y, Patel HJ, Patel MR, Patel PD, Rodina A, Patel Y, Gozman A, Maharaj R, Clement CC, Lu A, Young JC, Chiosis G.
Taldone T, et al.
J Med Chem. 2014 Feb 27;57(4):1208-24. doi: 10.1021/jm401552y. Epub 2014 Feb 18.
J Med Chem. 2014.
PMID: 24548239
Free PMC article.
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Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70.
Kang Y, Taldone T, Patel HJ, Patel PD, Rodina A, Gozman A, Maharaj R, Clement CC, Patel MR, Brodsky JL, Young JC, Chiosis G.
Kang Y, et al.
J Med Chem. 2014 Feb 27;57(4):1188-207. doi: 10.1021/jm401551n. Epub 2014 Feb 18.
J Med Chem. 2014.
PMID: 24548207
Free PMC article.
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