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Cross-elicitation responses to 2-methoxymethyl-p-phenylenediamine in p-phenylenediamine-allergic individuals: Results from open use testing and diagnostic patch testing.
Schuttelaar ML, Dittmar D, Burgerhof JGM, Blömeke B, Goebel C. Schuttelaar ML, et al. Contact Dermatitis. 2018 Nov;79(5):288-294. doi: 10.1111/cod.13078. Epub 2018 Aug 7. Contact Dermatitis. 2018. PMID: 30084179 Free PMC article.
Because of its lower sensitization potency, the PPD derivative 2-methoxymethyl-p-phenylenediamine (ME-PPD) has been developed as an alternative hair dye for primary prevention. ...
Because of its lower sensitization potency, the PPD derivative 2-methoxymethyl-p-phenylenediamine (ME-PPD) has b …
Cross-elicitation responses to 2-methoxymethyl-p-phenylenediamine under hair dye use conditions in p-phenylenediamine-allergic individuals.
Blömeke B, Pot LM, Coenraads PJ, Hennen J, Kock M, Goebel C. Blömeke B, et al. Br J Dermatol. 2015 Apr;172(4):976-80. doi: 10.1111/bjd.13412. Epub 2015 Feb 26. Br J Dermatol. 2015. PMID: 25234507
OBJECTIVES: Investigation of the elicitation response to the new, less-sensitizing PPD alternative 2-methoxymethyl-p-phenylenediamine (ME-PPD) under simulated hair dye use conditions. ...
OBJECTIVES: Investigation of the elicitation response to the new, less-sensitizing PPD alternative 2-methoxymethyl-p- …
Introduction of a methoxymethyl side chain into p-phenylenediamine attenuates its sensitizing potency and reduces the risk of allergy induction.
Goebel C, Troutman J, Hennen J, Rothe H, Schlatter H, Gerberick GF, Blömeke B. Goebel C, et al. Toxicol Appl Pharmacol. 2014 Feb 1;274(3):480-7. doi: 10.1016/j.taap.2013.11.016. Epub 2013 Dec 10. Toxicol Appl Pharmacol. 2014. PMID: 24333256
With introduction of a methoxymethyl side chain we found the primary intermediate 2-methoxymethyl-p-phenylenediamine (ME-PPD) with excellent hair coloring performance but significantly reduced sensitizing properties compared to PPD and PTD: In vitro, M …
With introduction of a methoxymethyl side chain we found the primary intermediate 2-methoxymethyl-p-phenylenediamine …