Pathogenesis of Paget disease of bone.
Ralston SH, Layfield R.
Ralston SH, et al.
Calcif Tissue Int. 2012 Aug;91(2):97-113. doi: 10.1007/s00223-012-9599-0. Epub 2012 Apr 29.
Calcif Tissue Int. 2012.
PMID: 22543925
Review.
Some patients are asymptomatic, whereas others develop complications such as pain, osteoarthritis, fracture, deformity, deafness, and nerve compression syndromes. PDB is primarily caused by dysregulation of osteoclast differentiation and function, and there is increasing e …
Some patients are asymptomatic, whereas others develop complications such as pain, osteoarthritis, fracture, deformity, deafness, and nerve …