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3-Bromo-4,5-dihydroxybenzaldehyde Protects Keratinocytes from Particulate Matter 2.5-Induced Damages.
Zhen AX, Piao MJ, Kang KA, Fernando PD, Herath HM, Cho SJ, Hyun JW. Zhen AX, et al. Antioxidants (Basel). 2023 Jun 20;12(6):1307. doi: 10.3390/antiox12061307. Antioxidants (Basel). 2023. PMID: 37372037 Free PMC article.
This study aimed to evaluate the protective effect of marine algae compound 3-bromo-4,5-dihydroxybenzaldehyde (3-BDB) on particulate matter 2.5 (PM(2.5))-induced skin cell damage in vitro and in vivo. ...Moreover, the mitogen-activated protein kinase s …
This study aimed to evaluate the protective effect of marine algae compound 3-bromo-4,5-dihydroxybenzaldehyde (3 …
Marine Compound 3-bromo-4,5-dihydroxybenzaldehyde Protects Skin Cells against Oxidative Damage via the Nrf2/HO-1 Pathway.
Ryu YS, Fernando PDSM, Kang KA, Piao MJ, Zhen AX, Kang HK, Koh YS, Hyun JW. Ryu YS, et al. Mar Drugs. 2019 Apr 19;17(4):234. doi: 10.3390/md17040234. Mar Drugs. 2019. PMID: 31010200 Free PMC article.
In this study, we aimed to illustrate the potential bio-effects of 3-bromo-4,5-dihydroxybenzaldehyde (3-BDB) on the antioxidant/cytoprotective enzyme heme oxygenase-1 (HO-1) in keratinocytes. ...Moreover, 3-BDB induced the phosphorylation of ERK …
In this study, we aimed to illustrate the potential bio-effects of 3-bromo-4,5-dihydroxybenzaldehyde (3-BDB) on …
3-Bromo-4,5-dihydroxybenzaldehyde Isolated from Polysiphonia morrowii Suppresses TNF-alpha/IFN-gamma-Stimulated Inflammation and Deterioration of Skin Barrier in HaCaT Keratinocytes.
Jayasinghe AMK, Han EJ, Kirindage KGIS, Fernando IPS, Kim EA, Kim J, Jung K, Kim KN, Heo SJ, Ahn G. Jayasinghe AMK, et al. Mar Drugs. 2022 Aug 31;20(9):563. doi: 10.3390/md20090563. Mar Drugs. 2022. PMID: 36135752 Free PMC article.
Polysiphonia morrowii is a well-known red alga that has promising pharmacological characteristics. The current study evaluates the protective effect of 3-bromo-4,5-dihydroxybenzaldehyde (BDB) isolated from P. morrowii on tumor necrosis factor (TNF)-alpha/inte …
Polysiphonia morrowii is a well-known red alga that has promising pharmacological characteristics. The current study evaluates the protectiv …
Protective effect of 3-bromo-4,5-dihydroxybenzaldehyde against PM(2.5)-induced cell cycle arrest and autophagy in keratinocytes.
Herath HMUL, Piao MJ, Kang KA, Fernando PDSM, Hyun JW. Herath HMUL, et al. Mol Cells. 2024 May;47(5):100066. doi: 10.1016/j.mocell.2024.100066. Epub 2024 Apr 26. Mol Cells. 2024. PMID: 38679413 Free PMC article.
Particulate matter 2.5 (PM(2.5)) poses a serious threat to human health and is responsible for respiratory disorders, cardiovascular diseases, and skin disorders. 3-Bromo-4,5-dihydroxybenzaldehyde (3-BDB), abundant in marine red algae, exhibits anti-in …
Particulate matter 2.5 (PM(2.5)) poses a serious threat to human health and is responsible for respiratory disorders, cardiovascular disease …
5-Bromo-3,4-dihydroxybenzaldehyde from Polysiphonia morrowii attenuate IgE/BSA-stimulated mast cell activation and passive cutaneous anaphylaxis in mice.
Han EJ, Fernando IPS, Kim EA, Kim J, Jung K, Kim SY, Cha SH, Kim KN, Heo SJ, Ahn G. Han EJ, et al. Biochem Pharmacol. 2020 Aug;178:114087. doi: 10.1016/j.bcp.2020.114087. Epub 2020 Jun 10. Biochem Pharmacol. 2020. PMID: 32531348
The present study investigates the anti-allergic activity of the marine algal bromophenol, 3-bromo-4,5-dihydroxybenzaldehyde (BDB), isolated from Polysiphonia morrowii Harvey in immunoglobulin (Ig)E/bovine serum albumin (BSA)-stimulated mouse bone marrow-deri …
The present study investigates the anti-allergic activity of the marine algal bromophenol, 3-bromo-4,5-dihydroxybenzaldehyd …
3-Bromo-4,5-Dihydroxybenzaldehyde Protects Against Myocardial Ischemia and Reperfusion Injury Through the Akt-PGC1alpha-Sirt3 Pathway.
Qin SG, Tian HY, Wei J, Han ZH, Zhang MJ, Hao GH, Liu X, Pan LF. Qin SG, et al. Front Pharmacol. 2018 Jul 10;9:722. doi: 10.3389/fphar.2018.00722. eCollection 2018. Front Pharmacol. 2018. PMID: 30042676 Free PMC article.
Natural marine products are useful candidates for the treatment of oxidative and inflammatory diseases, including myocardial ischemia. 3-bromo-4,5 - dihydroxybenzaldehyde (BDB), a natural bromophenol isolated from marine red algae, has been shown to display a …
Natural marine products are useful candidates for the treatment of oxidative and inflammatory diseases, including myocardial ischemia. 3 …
3-Bromo-4,5-dihydroxybenzaldehyde Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes.
Kim KC, Hyun YJ, Hewage SRKM, Piao MJ, Kang KA, Kang HK, Koh YS, Ahn MJ, Hyun JW. Kim KC, et al. Mar Drugs. 2017 Sep 18;15(9):291. doi: 10.3390/md15090291. Mar Drugs. 2017. PMID: 28926995 Free PMC article.
A natural bromophenol found in seaweeds, 3-bromo-4,5-dihydroxybenzaldehyde (BDB), has been shown to possess antioxidant effects. ...
A natural bromophenol found in seaweeds, 3-bromo-4,5-dihydroxybenzaldehyde (BDB), has been shown to possess antioxidant …
3-Chloro-4,5-dihydroxybenzaldehyde inhibits adipogenesis in 3T3-L1 adipocytes by regulating expression of adipogenic transcription factors and AMPK activation.
Kang MC, Ding Y, Kim J, Kim EA, Fernando IPS, Heo SJ, Lee SH. Kang MC, et al. Chem Biol Interact. 2018 May 1;287:27-31. doi: 10.1016/j.cbi.2018.04.001. Epub 2018 Apr 6. Chem Biol Interact. 2018. PMID: 29630878
The objective of the present study was to determine the inhibitory effect of 3-chloro-4,5-dihydroxybenzaldehyde (CDB) on adipogenesis in 3T3-L1 adipocyte cells. ...
The objective of the present study was to determine the inhibitory effect of 3-chloro-4,5-dihydroxybenzaldehyde (CDB) o …
Treatment with 3-Bromo-4,5-Dihydroxybenzaldehyde Improves Cardiac Function by Inhibiting Macrophage Infiltration in Mice.
Ji N, Lou H, Gong X, Fu T, Ni S. Ji N, et al. Korean Circ J. 2018 Oct;48(10):933-943. doi: 10.4070/kcj.2017.0373. Korean Circ J. 2018. PMID: 30238711 Free PMC article.
BACKGROUND AND OBJECTIVES: Appropriate inflammatory response is necessary for cardiac repairing after acute myocardial infarction (MI). Three-Bromo-4,5-dihydroxybenzaldehyde (BDB) is a potent antioxidant and natural bromophenol compound derived from red algae. ...
BACKGROUND AND OBJECTIVES: Appropriate inflammatory response is necessary for cardiac repairing after acute myocardial infarction (MI). Thre …
49 results