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Acidic Microenvironment Determines Antibiotic Susceptibility and Biofilm Formation of Pseudomonas aeruginosa.

Lin Q, Pilewski JM, Di YP. Lin Q, et al. Front Microbiol. 2021 Nov 19;12:747834. doi: 10.3389/fmicb.2021.747834. eCollection 2021. Front Microbiol. 2021. PMID: 34867864 Free PMC article.

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Airway acidification initiates host defense abnormalities in cystic fibrosis mice.

Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB Jr, Ostedgaard LS, Stoltz DA, Randak CO, Welsh MJ. Shah VS, et al. Science. 2016 Jan 29;351(6272):503-7. doi: 10.1126/science.aad5589. Science. 2016. PMID: 26823428 Free PMC article.

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Impaired butyrate absorption in the proximal colon, low serum butyrate and diminished central effects of butyrate on blood pressure in spontaneously hypertensive rats.

Yang T, Magee KL, Colon-Perez LM, Larkin R, Liao YS, Balazic E, Cowart JR, Arocha R, Redler T, Febo M, Vickroy T, Martyniuk CJ, Reznikov LR, Zubcevic J. Yang T, et al. Acta Physiol (Oxf). 2019 Jun;226(2):e13256. doi: 10.1111/apha.13256. Epub 2019 Feb 20. Acta Physiol (Oxf). 2019. PMID: 30656835 Free PMC article.

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Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.

Stoltz DA, Rokhlina T, Ernst SE, Pezzulo AA, Ostedgaard LS, Karp PH, Samuel MS, Reznikov LR, Rector MV, Gansemer ND, Bouzek DC, Abou Alaiwa MH, Hoegger MJ, Ludwig PS, Taft PJ, Wallen TJ, Wohlford-Lenane C, McMenimen JD, Chen JH, Bogan KL, Adam RJ, Hornick EE, Nelson GA 4th, Hoffman EA, Chang EH, Zabner J, McCray PB Jr, Prather RS, Meyerholz DK, Welsh MJ. Stoltz DA, et al. J Clin Invest. 2013 Jun;123(6):2685-93. doi: 10.1172/JCI68867. Epub 2013 May 8. J Clin Invest. 2013. PMID: 23676501 Free PMC article.

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Luminal acetylcholine does not affect the activity of the CFTR in tracheal epithelia of pigs.

Dittrich NP, Kummer W, Clauss WG, Fronius M. Dittrich NP, et al. Int Immunopharmacol. 2015 Nov;29(1):166-72. doi: 10.1016/j.intimp.2015.08.010. Epub 2015 Aug 15. Int Immunopharmacol. 2015. PMID: 26286842

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Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis.

Sorio C, Buffelli M, Angiari C, Ettorre M, Johansson J, Vezzalini M, Viviani L, Ricciardi M, Verzè G, Assael BM, Melotti P. Sorio C, et al. PLoS One. 2011;6(7):e22212. doi: 10.1371/journal.pone.0022212. Epub 2011 Jul 21. PLoS One. 2011. PMID: 21811577 Free PMC article.

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Innate immunity in the respiratory epithelium.

Parker D, Prince A. Parker D, et al. Am J Respir Cell Mol Biol. 2011 Aug;45(2):189-201. doi: 10.1165/rcmb.2011-0011RT. Epub 2011 Feb 17. Am J Respir Cell Mol Biol. 2011. PMID: 21330463 Free PMC article. Review.

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New insights into the pathogenesis of cystic fibrosis sinusitis.

Chang EH. Chang EH. Int Forum Allergy Rhinol. 2014 Feb;4(2):132-7. doi: 10.1002/alr.21252. Epub 2013 Nov 26. Int Forum Allergy Rhinol. 2014. PMID: 24282147 Free PMC article. Review.

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Transport properties in CFTR-/- knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na⁺ absorption.

Benedetto R, Centeio R, Ousingsawat J, Schreiber R, Janda M, Kunzelmann K. Benedetto R, et al. Pflugers Arch. 2020 Oct;472(10):1507-1519. doi: 10.1007/s00424-020-02440-y. Epub 2020 Jul 25. Pflugers Arch. 2020. PMID: 32712714 Free PMC article.

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Midkine in host defence.

Gela A, Jovic S, Nordin SL, Egesten A. Gela A, et al. Br J Pharmacol. 2014 Feb;171(4):859-69. doi: 10.1111/bph.12402. Br J Pharmacol. 2014. PMID: 24024937 Free PMC article. Review.

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