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Year Number of Results
2010 2
2011 4
2013 4
2014 3
2015 6
2016 3
2017 2
2018 6
2019 2
2020 1
2021 3
2022 1
2024 0

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A randomized, controlled trial of oral propranolol in infantile hemangioma.
Léauté-Labrèze C, Hoeger P, Mazereeuw-Hautier J, Guibaud L, Baselga E, Posiunas G, Phillips RJ, Caceres H, Lopez Gutierrez JC, Ballona R, Friedlander SF, Powell J, Perek D, Metz B, Barbarot S, Maruani A, Szalai ZZ, Krol A, Boccara O, Foelster-Holst R, Febrer Bosch MI, Su J, Buckova H, Torrelo A, Cambazard F, Grantzow R, Wargon O, Wyrzykowski D, Roessler J, Bernabeu-Wittel J, Valencia AM, Przewratil P, Glick S, Pope E, Birchall N, Benjamin L, Mancini AJ, Vabres P, Souteyrand P, Frieden IJ, Berul CI, Mehta CR, Prey S, Boralevi F, Morgan CC, Heritier S, Delarue A, Voisard JJ. Léauté-Labrèze C, et al. N Engl J Med. 2015 Feb 19;372(8):735-46. doi: 10.1056/NEJMoa1404710. N Engl J Med. 2015. PMID: 25693013 Free article. Clinical Trial.
METHODS: We performed a multicenter, randomized, double-blind, adaptive, phase 2-3 trial assessing the efficacy and safety of a pediatric-specific oral propranolol solution in infants 1 to 5 months of age with proliferating infantile hemangioma requiri …
METHODS: We performed a multicenter, randomized, double-blind, adaptive, phase 2-3 trial assessing the efficacy and safety of a pediatric-sp …
Noninferiority and Safety of Nadolol vs Propranolol in Infants With Infantile Hemangioma: A Randomized Clinical Trial.
Pope E, Lara-Corrales I, Sibbald C, Liy-Wong C, Kanigsberg N, Drolet B, Ma J. Pope E, et al. JAMA Pediatr. 2022 Jan 1;176(1):34-41. doi: 10.1001/jamapediatrics.2021.4565. JAMA Pediatr. 2022. PMID: 34747977 Free PMC article. Clinical Trial.
IMPORTANCE: Propranolol for infantile hemangiomas (IH) has been shown to be effective and relatively safe. ...INTERVENTIONS: Oral propranolol and nadolol in escalating doses up to 2 mg/kg/d. ...
IMPORTANCE: Propranolol for infantile hemangiomas (IH) has been shown to be effective and relatively safe. ...INTERVENTIONS: …
Efficacy and Safety of Propranolol vs Atenolol in Infants With Problematic Infantile Hemangiomas: A Randomized Clinical Trial.
Ji Y, Chen S, Yang K, Zhang X, Zhou J, Li L, Xiang B, Qiu T, Dai S, Jiang X, Lu G, Qiu L, Kong F, Zhang Y. Ji Y, et al. JAMA Otolaryngol Head Neck Surg. 2021 Jul 1;147(7):599-607. doi: 10.1001/jamaoto.2021.0454. JAMA Otolaryngol Head Neck Surg. 2021. PMID: 33856430 Free PMC article. Clinical Trial.
IMPORTANCE: Propranolol has become the first-line therapy for problematic infantile hemangiomas (IHs) that require systemic therapy. ...At 1 and 4 weeks after treatment, and thereafter, the hemangioma activity score in the atenolol group aligned with the p …
IMPORTANCE: Propranolol has become the first-line therapy for problematic infantile hemangiomas (IHs) that require systemic th …
Efficacy and Safety of Topical Timolol for the Treatment of Infantile Hemangioma in the Early Proliferative Stage: A Randomized Clinical Trial.
Muñoz-Garza FZ, Ríos M, Roé-Crespo E, Bernabeu-Wittel J, Montserrat-García MT, Puig L, Gich I, Baselga E. Muñoz-Garza FZ, et al. JAMA Dermatol. 2021 May 1;157(5):583-587. doi: 10.1001/jamadermatol.2021.0596. JAMA Dermatol. 2021. PMID: 33825828 Free PMC article. Clinical Trial.
IMPORTANCE: Treatment of infantile hemangioma (IH) with topical timolol in the first 2 months of life (early proliferative phase) may prevent further growth and the need for treatment with oral propranolol. ...
IMPORTANCE: Treatment of infantile hemangioma (IH) with topical timolol in the first 2 months of life (early proliferative pha …
Propranolol in the Treatment of Infantile Hemangiomas: A Meta-Analysis in Chinese Patients.
Li LL, Yan L, Luo MX, Cai YX, Mi XB, Zhang TD. Li LL, et al. Pediatr Dermatol. 2015 Sep-Oct;32(5):e210-4. doi: 10.1111/pde.12627. Epub 2015 Jun 10. Pediatr Dermatol. 2015. PMID: 26060892 Review.
A meta-analysis was conducted to evaluate the efficacy of propranolol in the treatment of infantile hemangiomas (IHs) in Chinese infants. A statistically significant difference was found between infants treated using propranolol and those treated using cortic …
A meta-analysis was conducted to evaluate the efficacy of propranolol in the treatment of infantile hemangiomas (IHs) in Chine …
Propranolol versus captopril in the treatment of infantile hemangioma (IH): A randomized controlled trial.
Zaher H, Rasheed H, El-Komy MM, Hegazy RA, Gawdat HI, Abdel Halim DM, Abdel Hay RM, Hegazy RA, Mohy AM. Zaher H, et al. J Am Acad Dermatol. 2016 Mar;74(3):499-505. doi: 10.1016/j.jaad.2015.09.061. Epub 2015 Dec 11. J Am Acad Dermatol. 2016. PMID: 26685718 Clinical Trial.
BACKGROUND: Renin-angiotensin system components have been demonstrated in the biology of infantile hemangioma (IH). Captopril, an angiotensin-converting enzyme inhibitor, is proposed as a therapeutic alternative to oral propranolol. ...RESULTS: Clinica …
BACKGROUND: Renin-angiotensin system components have been demonstrated in the biology of infantile hemangioma (IH). Captopril, …
A randomized controlled trial of propranolol for infantile hemangiomas.
Hogeling M, Adams S, Wargon O. Hogeling M, et al. Pediatrics. 2011 Aug;128(2):e259-66. doi: 10.1542/peds.2010-0029. Epub 2011 Jul 25. Pediatrics. 2011. PMID: 21788220 Clinical Trial.
OBJECTIVE: Propranolol hydrochloride is a safe and effective medication for treating infantile hemangiomas (IHs), with decreases in IH volume, color, and elevation. METHODS: Forty children between the ages of 9 weeks and 5 years with facial IHs or IHs in sites with …
OBJECTIVE: Propranolol hydrochloride is a safe and effective medication for treating infantile hemangiomas (IHs), with decreas …
Propranolol and infantile hemangiomas: different routes of administration, a randomized clinical trial.
Zaher H, Rasheed H, Esmat S, Hegazy RA, Gawdat HI, Hegazy RA, El-Komy M, Abdelhalim DM. Zaher H, et al. Eur J Dermatol. 2013 Sep-Oct;23(5):646-52. doi: 10.1684/ejd.2013.2146. Eur J Dermatol. 2013. PMID: 24135427 Clinical Trial.
Oral propranolol has become the treatment of choice of infantile hemangiomas (IH)s. ...Nevertheless, in properly selected patients with IHs, we recommend the usage of oral propranolol. Topically administered propranolol could be considere …
Oral propranolol has become the treatment of choice of infantile hemangiomas (IH)s. ...Nevertheless, in properly select …
Propranolol vs prednisolone for symptomatic proliferating infantile hemangiomas: a randomized clinical trial.
Bauman NM, McCarter RJ, Guzzetta PC, Shin JJ, Oh AK, Preciado DA, He J, Greene EA, Puttgen KB. Bauman NM, et al. JAMA Otolaryngol Head Neck Surg. 2014 Apr;140(4):323-30. doi: 10.1001/jamaoto.2013.6723. JAMA Otolaryngol Head Neck Surg. 2014. PMID: 24526257 Clinical Trial.
IMPORTANCE: While propranolol is touted as superior to prednisolone for treating infantile hemangiomas (IH), a randomized clinical trial (RCT) comparing the outcome and tolerability of these medications for symptomatic, proliferating IH has not been reported. ...All …
IMPORTANCE: While propranolol is touted as superior to prednisolone for treating infantile hemangiomas (IH), a randomized clin …
Infantile Hemangiomas in the Head and Neck Region.
Adams DM, Ricci KW. Adams DM, et al. Otolaryngol Clin North Am. 2018 Feb;51(1):77-87. doi: 10.1016/j.otc.2017.09.009. Otolaryngol Clin North Am. 2018. PMID: 29217069 Review.
Medical interventions for high-risk patients include topical and systemic therapies, including oral propranolol, which has revolutionized the management of IHs over the past recent years. In the following article, the authors aim to provide a review of the natural h …
Medical interventions for high-risk patients include topical and systemic therapies, including oral propranolol, which has rev …
30 results