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Year Number of Results
1995 1
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2003 27
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2005 28
2006 45
2007 41
2008 59
2009 52
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1,156 results

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Page 1
Gene Expression of Abcc2 and Its Regulation by Chicken Xenobiotic Receptor.
Gao Y, Deng H, Zhao Y, Li M, Wang L, Zhang Y. Gao Y, et al. Toxics. 2024 Jan 10;12(1):55. doi: 10.3390/toxics12010055. Toxics. 2024. PMID: 38251011 Free PMC article.
We further confirmed that Abcc2 gene regulation is dependent on CXR, by overexpressing and interfering with CXR, respectively. ...Animal experiments demonstrated that metyrapone and ivermectin induced Abcc2 in the liver, kidney, and duodenum of chickens. Toge …
We further confirmed that Abcc2 gene regulation is dependent on CXR, by overexpressing and interfering with CXR, respectively. …
Systematic identification of silencers in human cells.
Pang B, Snyder MP. Pang B, et al. Nat Genet. 2020 Mar;52(3):254-263. doi: 10.1038/s41588-020-0578-5. Epub 2020 Feb 24. Nat Genet. 2020. PMID: 32094911 Free PMC article.
Many of these noncoding regions contain important regulatory sequences that control gene expression. To date, most studies have focused on activators such as enhancers, but regions that repress gene expression-silencers-have not been systematically studied. ...Delet …
Many of these noncoding regions contain important regulatory sequences that control gene expression. To date, most studies have focus …
Mutation analysis of the ABCC2 gene in Chinese patients with Dubin-Johnson syndrome.
Wu L, Zhang W, Jia S, Zhao X, Zhou D, Xu A, Duan W, Wu Z, Li H, Zheng S, Nan Y, Jia J, Huang J, Ou X. Wu L, et al. Exp Ther Med. 2018 Nov;16(5):4201-4206. doi: 10.3892/etm.2018.6682. Epub 2018 Sep 3. Exp Ther Med. 2018. PMID: 30344695 Free PMC article.
In the present study, the mutation pattern of the ABCC2 gene in Chinese patients with DJS was investigated. A total of 7 clinically confirmed patients with DJS were enrolled, and mutation analysis of the ABCC2 gene was performed by Sanger sequencing of …
In the present study, the mutation pattern of the ABCC2 gene in Chinese patients with DJS was investigated. A total of 7 clini …
In silico screening and analysis of single-nucleotide polymorphic variants of the ABCC2 gene affecting Dubin-Johnson syndrome.
Sharma P, Sharma S. Sharma P, et al. Arab J Gastroenterol. 2022 Aug;23(3):172-187. doi: 10.1016/j.ajg.2022.03.003. Epub 2022 Apr 25. Arab J Gastroenterol. 2022. PMID: 35477852
Multidrug resistance protein 2 (MRP2) encoded by the ABCC2 gene is one of the main regulators of the export of bilirubin to respective sites. ABCC2 gene mutations have widely drawn attention in the pathology of DJS in various populations. ...
Multidrug resistance protein 2 (MRP2) encoded by the ABCC2 gene is one of the main regulators of the export of bilirubin to re …
Genetic variability of the ABCC2 gene and clinical outcomes in pancreatic cancer patients.
Gentiluomo M, Puchalt García P, Galeotti AA, Talar-Wojnarowska R, Tjaden C, Tavano F, Strobel O, Kupcinskas J, Neoptolemos J, Hegyi P, Costello E, Pezzilli R, Sperti C, Lawlor RT, Capurso G, Szentesi A, Soucek P, Vodicka P, Lovecek M, Hackert T, Cavestro GM, Milanetto AC, Canzian F, Campa D. Gentiluomo M, et al. Carcinogenesis. 2019 Jun 10;40(4):544-550. doi: 10.1093/carcin/bgz006. Carcinogenesis. 2019. PMID: 30629142
Moreover, single nucleotide polymorphisms (SNPs) in the gene have been associated with differential outcomes and prognosis in several tumour types. The aim of this study was to investigate the possible association between SNPs in the ABCC2 gene and overall su …
Moreover, single nucleotide polymorphisms (SNPs) in the gene have been associated with differential outcomes and prognosis in several …
The ABCC2 c.-24C>T polymorphism increases the risk of resistance to antiepileptic drugs: A meta-analysis.
Qian L, Fang S, Yan YL, Zeng SS, Xu ZJ, Gong ZC. Qian L, et al. J Clin Neurosci. 2017 Mar;37:6-14. doi: 10.1016/j.jocn.2016.10.014. Epub 2016 Nov 2. J Clin Neurosci. 2017. PMID: 27816260 Review.
Several studies examined a possible link between multidrug resistance-associated protein 2 (ABCC2) gene variants and the risk of resistance to antiepileptic drugs (AEDs) in epilepsy, but the results were contradictory. ...We searched Embase, PubMed, the Cochrane Lib …
Several studies examined a possible link between multidrug resistance-associated protein 2 (ABCC2) gene variants and the risk …
Effects of MTHFR and ABCC2 gene polymorphisms on antiepileptic drug responsiveness in Jordanian epileptic patients.
Al-Eitan LN, Al-Dalalah IM, Mustafa MM, Alghamdi MA, Elshammari AK, Khreisat WH, Aljamal HA. Al-Eitan LN, et al. Pharmgenomics Pers Med. 2019 Jun 10;12:87-95. doi: 10.2147/PGPM.S211490. eCollection 2019. Pharmgenomics Pers Med. 2019. PMID: 31354331 Free PMC article.
OBJECTIVES: This study designed to evaluate the pharmacogenomics of MTHFR and ABCC2 genes, and their association with epilepsy susceptibility among Jordanian population. ...Regarding ABCC2 gene, rs717620 was of linkage with generalized and GTCE subtype …
OBJECTIVES: This study designed to evaluate the pharmacogenomics of MTHFR and ABCC2 genes, and their association with epilepsy …
SCN1A, ABCC2 and UGT2B7 gene polymorphisms in association with individualized oxcarbazepine therapy.
Ma CL, Wu XY, Jiao Z, Hong Z, Wu ZY, Zhong MK. Ma CL, et al. Pharmacogenomics. 2015;16(4):347-60. doi: 10.2217/pgs.14.186. Pharmacogenomics. 2015. PMID: 25823783
AIM: Associations between the effects of SCN1A, SCN2A, ABCC2 and UGT2B7 genetic polymorphisms and oxcarbazepine (OXC) maintenance doses in Han Chinese epileptic patients were investigated. ...RESULTS: Carriers of the SCN1A IVS5-91G>A, UGT2B7 c.802T>C and ABCC2 …
AIM: Associations between the effects of SCN1A, SCN2A, ABCC2 and UGT2B7 genetic polymorphisms and oxcarbazepine (OXC) maintenance dos …
Literature review and report of three cases of Dubin-Johnson syndrome related to ABCC2 gene mutations in children.
You SJ, Sun YX, Zhang J, He Q, Wu XM, Hu Y. You SJ, et al. Am J Transl Res. 2021 May 15;13(5):4477-4488. eCollection 2021. Am J Transl Res. 2021. PMID: 34150028 Free PMC article.
OBJECTIVE: The aim of the present study was to analyze the clinical features of Dubin-Johnson syndrome (DJS) related to ABCC2 gene mutations in children and to review the relevant literature to improve understanding of this type of genetic disease and reduce misdiag …
OBJECTIVE: The aim of the present study was to analyze the clinical features of Dubin-Johnson syndrome (DJS) related to ABCC2 gene …
Mis-splicing of the ABCC2 gene linked with Bt toxin resistance in Helicoverpa armigera.
Xiao Y, Zhang T, Liu C, Heckel DG, Li X, Tabashnik BE, Wu K. Xiao Y, et al. Sci Rep. 2014 Aug 26;4:6184. doi: 10.1038/srep06184. Sci Rep. 2014. PMID: 25154974 Free PMC article.
Here we compared the ABCC2 gene of Helicoverpa armigera (HaABCC2) between susceptible strains and a laboratory-selected strain with >1,000-fold resistance to Cry1Ac relative its susceptible parent strain. ...These results provide the first evidence that mis-splic …
Here we compared the ABCC2 gene of Helicoverpa armigera (HaABCC2) between susceptible strains and a laboratory-selected strain …
1,156 results