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Year Number of Results
2004 1
2006 1
2008 1
2010 1
2011 2
2012 1
2013 1
2014 3
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2016 2
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2020 7
2021 4
2022 8
2023 1
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33 results

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circSLC25A13 acts as a ceRNA to regulate AML progression via miR-616-3p/ADCY2 axis.
Wei W, Pan J, Wang J, Mao S, Qian Y, Lin X, Ling Q, Ye W, Zhou Y, Zhao Y, Huang J, Huang X, Ma Z, Wang H, Li C, Sun J, Jin J. Wei W, et al. Mol Carcinog. 2023 Oct;62(10):1546-1562. doi: 10.1002/mc.23598. Epub 2023 Jul 26. Mol Carcinog. 2023. PMID: 37493101
Mechanistically, circSLC25A13 played as a microRNA sponge of miR-616-3p, which inhibited the expression of adenylate cyclase 2 (ADCY2). Downregulation of miR-616-3p and overexpression of ADCY2 partially rescued circSLC25A13 deficient induced cell growth arrest. In s …
Mechanistically, circSLC25A13 played as a microRNA sponge of miR-616-3p, which inhibited the expression of adenylate cyclase 2 (ADCY2 …
ADCY2 rs10059539 C>T polymorphism confers a decreased risk of hepatocellular carcinoma in Chinese Han women.
Chao X, Miao F, Feng X, Shi H, Wang Y, Wu J, Zhao L, Zhang W, Jiang C. Chao X, et al. Eur J Cancer Prev. 2021 Sep 1;30(5):351-356. doi: 10.1097/CEJ.0000000000000638. Eur J Cancer Prev. 2021. Retraction in: Eur J Cancer Prev. 2022 Jan 1;31(1):105. doi: 10.1097/CEJ.0000000000000729. PMID: 34010241 Retracted.
OBJECTIVE: Hepatocellular carcinoma (HCC) poses a serious threat to human health. ADCY2 gene polymorphisms may be related to HCC susceptibility. Therefore, we investigated whether ADCY2 gene polymorphisms are correlated to the risk of HCC in a Chinese Han population …
OBJECTIVE: Hepatocellular carcinoma (HCC) poses a serious threat to human health. ADCY2 gene polymorphisms may be related to HCC susc …
Assessment of ADCY9 polymorphisms and colorectal cancer risk in the Chinese Han population.
Li H, Liu Y, Liu J, Sun Y, Wu J, Xiong Z, Zhang Y, Li B, Jin T. Li H, et al. J Gene Med. 2021 Feb;23(2):e3298. doi: 10.1002/jgm.3298. Epub 2021 Jan 15. J Gene Med. 2021. PMID: 33232543
BACKGROUND: Recently, ADCY9 has been found to be highly expressed in colon cancer, and high ADCY9 expressionis a poor prognostic factor of colon cancer. ...Future association and functional studies are required to confirm our findings and explore the mechanism of …
BACKGROUND: Recently, ADCY9 has been found to be highly expressed in colon cancer, and high ADCY9 expressionis a poor prognostic fact …
Systems-level differential gene expression analysis reveals new genetic variants of oral cancer.
Abbas SZ, Qadir MI, Muhammad SA. Abbas SZ, et al. Sci Rep. 2020 Sep 4;10(1):14667. doi: 10.1038/s41598-020-71346-7. Sci Rep. 2020. PMID: 32887903 Free PMC article.
Oral cancer (OC) ranked as eleventh malignancy worldwide, with the increasing incidence among young patients. ...The mutational analysis revealed the sequence predicted disordered region of 14%, 12.5%, 10.5% for ADCY2, CYP1B1, and C7 respectively. The MiRNA target p …
Oral cancer (OC) ranked as eleventh malignancy worldwide, with the increasing incidence among young patients. ...The mutational analy …
Identification of adenylate cyclase 2 methylation in bladder cancer with implications for prognosis and immunosuppressive microenvironment.
Yang J, Xu J, Gao Q, Wu F, Han W, Yu C, Shi Y, Qiu Y, Chen Y, Zhou X. Yang J, et al. Front Oncol. 2022 Oct 14;12:1025195. doi: 10.3389/fonc.2022.1025195. eCollection 2022. Front Oncol. 2022. PMID: 36313639 Free PMC article.
To compare the relationship between key genes and the prognosis of BCa patients, we further investigated ADCY2 and found that ADCY2 can be a potential clinical biomarker in BCa prognosis and immunotherapy response prediction. In human BCa 5637 and MGH1 cells, we dev …
To compare the relationship between key genes and the prognosis of BCa patients, we further investigated ADCY2 and found that ADCY …
A Novel Lipid Prognostic Signature of ADCY2, LIPE, and OLR1 in Head and Neck Squamous Cell Carcinoma.
Gao X, Zhao N, Dong L, Zheng X, Zhang Y, Ding C, Zhao S, Ma Z, Wang Y. Gao X, et al. Front Oncol. 2021 Nov 25;11:735993. doi: 10.3389/fonc.2021.735993. eCollection 2021. Front Oncol. 2021. PMID: 34900686 Free PMC article.
Lipid metabolic reprogramming is an emerging carcinogen as its role in fulfilling cancer growth and spread. However, little is known about the correlation between lipid metabolism and HNSCC. ...The LRPS-high group was significantly related to perineural invasion of canc …
Lipid metabolic reprogramming is an emerging carcinogen as its role in fulfilling cancer growth and spread. However, little is known …
Identification of fusions with potential clinical significance in melanoma.
Moran JMT, Le LP, Nardi V, Golas J, Farahani AA, Signorelli S, Onozato ML, Foreman RK, Duncan LM, Lawrence DP, Lennerz JK, Dias-Santagata D, Hoang MP. Moran JMT, et al. Mod Pathol. 2022 Dec;35(12):1837-1847. doi: 10.1038/s41379-022-01138-z. Epub 2022 Jul 23. Mod Pathol. 2022. PMID: 35871080 Free article.
We identified two novel rearrangements: NAGS::MAST2 and NOTCH1::GNB1; and two fusions that have been reported in other malignancies but not in melanoma: CANT1::ETV4 (prostate cancer) and CCDC6::RET (thyroid cancer). Additional fusions, previously reported in melanom …
We identified two novel rearrangements: NAGS::MAST2 and NOTCH1::GNB1; and two fusions that have been reported in other malignancies but not …
Timing of chronic obstructive pulmonary disease diagnosis in lung cancer prognosis: a clinical and genomic-based study.
Dai J, He Y, Maneenil K, Liu H, Liu M, Guo Q, Bennett AC, Stoddard SM, Wampfler JA, Jiang G, Yang P. Dai J, et al. Transl Lung Cancer Res. 2021 Mar;10(3):1209-1220. doi: 10.21037/tlcr-20-1017. Transl Lung Cancer Res. 2021. PMID: 33889503 Free PMC article.
BACKGROUND: A two-phase study (clinical and genomic-based) was conducted to evaluate the effect of timing of chronic obstructive pulmonary disease (COPD) diagnosis on lung cancer outcomes. METHODS: The prognostic influence of COPD was investigated in a clinical cohort of 1 …
BACKGROUND: A two-phase study (clinical and genomic-based) was conducted to evaluate the effect of timing of chronic obstructive pulmonary d …
Investigation of the molecular mechanisms underlying metastasis in prostate cancer by gene expression profiling.
Zhang X, Yao X, Qin C, Luo P, Zhang J. Zhang X, et al. Exp Ther Med. 2016 Aug;12(2):925-932. doi: 10.3892/etm.2016.3376. Epub 2016 May 20. Exp Ther Med. 2016. PMID: 27446297 Free PMC article.
Furthermore, some DEGs (CAMK2D and PCDH17) were observed to be regulated by miR-30, whereas others (ADCY2, MAF, SH3BP4 and PCDH17) were modulated by miR-182. Additionally, ADCY2 and CAMK2D were distinctly enriched in the calcium signaling pathway. The present study …
Furthermore, some DEGs (CAMK2D and PCDH17) were observed to be regulated by miR-30, whereas others (ADCY2, MAF, SH3BP4 and PCDH17) we …
33 results