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ADGRD1 as a Potential Prognostic and Immunological Biomarker in Non-Small-Cell Lung Cancer.
Lv M, Li X, Tian W, Yang H, Zhou B. Lv M, et al. Biomed Res Int. 2022 Nov 22;2022:5699892. doi: 10.1155/2022/5699892. eCollection 2022. Biomed Res Int. 2022. PMID: 36457341 Free PMC article.
ADGRD1 (GPR133), an adhesion G protein-coupled receptor (GPCR), has been linked to cancer. ...ADGRD1 expression and regulation may be critical in determining NSCLC prognosis....
ADGRD1 (GPR133), an adhesion G protein-coupled receptor (GPCR), has been linked to cancer. ...ADGRD1 expression and reg …
PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma.
Frenster JD, Erdjument-Bromage H, Stephan G, Ravn-Boess N, Wang S, Liu W, Bready D, Wilcox J, Kieslich B, Jankovic M, Wilde C, Horn S, Sträter N, Liebscher I, Schöneberg T, Fenyo D, Neubert TA, Placantonakis DG. Frenster JD, et al. Cell Rep. 2023 Jul 25;42(7):112679. doi: 10.1016/j.celrep.2023.112679. Epub 2023 Jun 23. Cell Rep. 2023. PMID: 37354459 Free PMC article.
The adhesion G-protein-coupled receptor GPR133 (ADGRD1) supports growth of the brain malignancy glioblastoma. How the extracellular interactome of GPR133 in glioblastoma modulates signaling remains unknown. ...
The adhesion G-protein-coupled receptor GPR133 (ADGRD1) supports growth of the brain malignancy glioblastoma. How the extracellular i …
Modulation of GPR133 (ADGRD1) Signaling by its Intracellular Interaction Partner Extended Synaptotagmin 1 (ESYT1).
Stephan G, Erdjument-Bromage H, Liu W, Frenster JD, Ravn-Boess N, Bready D, Cai J, Fenyo D, Neubert T, Placantonakis DG. Stephan G, et al. bioRxiv [Preprint]. 2023 Feb 9:2023.02.09.527921. doi: 10.1101/2023.02.09.527921. bioRxiv. 2023. PMID: 36798364 Free PMC article. Updated. Preprint.
GPR133 (ADGRD1) is an adhesion G protein-coupled receptor that signals through Galphas and is required for growth of glioblastoma (GBM), an aggressive brain malignancy. ...
GPR133 (ADGRD1) is an adhesion G protein-coupled receptor that signals through Galphas and is required for growth of glioblastoma (GB …
Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1.
Stephan G, Haddock S, Wang S, Erdjument-Bromage H, Liu W, Ravn-Boess N, Frenster JD, Bready D, Cai J, Ronnen R, Sabio-Ortiz J, Fenyo D, Neubert TA, Placantonakis DG. Stephan G, et al. Cell Rep. 2024 May 28;43(5):114229. doi: 10.1016/j.celrep.2024.114229. Epub 2024 May 16. Cell Rep. 2024. PMID: 38758649 Free article.
GPR133 (ADGRD1) is an adhesion G-protein-coupled receptor that signals through Galphas/cyclic AMP (cAMP) and is required for the growth of glioblastoma (GBM), an aggressive brain malignancy. ...
GPR133 (ADGRD1) is an adhesion G-protein-coupled receptor that signals through Galphas/cyclic AMP (cAMP) and is required for the grow …
Activation of the adhesion G protein-coupled receptor GPR133 by antibodies targeting its N-terminus.
Stephan G, Frenster JD, Liebscher I, Placantonakis DG. Stephan G, et al. J Biol Chem. 2022 Jun;298(6):101949. doi: 10.1016/j.jbc.2022.101949. Epub 2022 Apr 18. J Biol Chem. 2022. PMID: 35447113 Free PMC article.
We recently demonstrated that GPR133 (ADGRD1), an adhesion G protein-coupled receptor involved in raising cytosolic cAMP levels, is necessary for growth of glioblastoma (GBM) and is de novo expressed in GBM relative to normal brain tissue. ...
We recently demonstrated that GPR133 (ADGRD1), an adhesion G protein-coupled receptor involved in raising cytosolic cAMP levels, is n …
Functional impact of intramolecular cleavage and dissociation of adhesion G protein-coupled receptor GPR133 (ADGRD1) on canonical signaling.
Frenster JD, Stephan G, Ravn-Boess N, Bready D, Wilcox J, Kieslich B, Wilde C, Sträter N, Wiggin GR, Liebscher I, Schöneberg T, Placantonakis DG. Frenster JD, et al. J Biol Chem. 2021 Jan-Jun;296:100798. doi: 10.1016/j.jbc.2021.100798. Epub 2021 May 20. J Biol Chem. 2021. PMID: 34022221 Free PMC article.
GPR133 (ADGRD1), an adhesion G protein-coupled receptor (GPCR) whose canonical signaling activates G(alphaS)-mediated generation of cytosolic cAMP, has been shown to be necessary for the growth of glioblastoma (GBM), a brain malignancy. ...
GPR133 (ADGRD1), an adhesion G protein-coupled receptor (GPCR) whose canonical signaling activates G(alphaS)-mediated generation of c …
GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth.
Bayin NS, Frenster JD, Kane JR, Rubenstein J, Modrek AS, Baitalmal R, Dolgalev I, Rudzenski K, Scarabottolo L, Crespi D, Redaelli L, Snuderl M, Golfinos JG, Doyle W, Pacione D, Parker EC, Chi AS, Heguy A, MacNeil DJ, Shohdy N, Zagzag D, Placantonakis DG. Bayin NS, et al. Oncogenesis. 2016 Oct 24;5(10):e263. doi: 10.1038/oncsis.2016.63. Oncogenesis. 2016. PMID: 27775701 Free PMC article.
Here, we use primary human tumor biospecimens and cultures to identify GPR133 (ADGRD1), an orphan member of the adhesion family of G-protein-coupled receptors, as a critical regulator of the response to hypoxia and tumor growth in GBM. ...
Here, we use primary human tumor biospecimens and cultures to identify GPR133 (ADGRD1), an orphan member of the adhesion family of G- …
Differentially expressed long noncoding RNAs and regulatory mechanism of LINC02407 in human gastric adenocarcinoma.
Zhou LL, Jiao Y, Chen HM, Kang LH, Yang Q, Li J, Guan M, Zhu G, Liu FQ, Wang S, Bai X, Song YQ. Zhou LL, et al. World J Gastroenterol. 2019 Oct 21;25(39):5973-5990. doi: 10.3748/wjg.v25.i39.5973. World J Gastroenterol. 2019. PMID: 31660034 Free PMC article.
Western blot analysis showed that adhesion G protein-coupled receptor D1 (ADGRD1) was regulated by the LINC02407-miR-6845-5p/miR-4455-ADGRD1 pathways. CONCLUSION: LINC02407 plays a role in GC through the LINC02407-miR-6845-5p/miR-4455-ADGRD1 pathways, and thu …
Western blot analysis showed that adhesion G protein-coupled receptor D1 (ADGRD1) was regulated by the LINC02407-miR-6845-5p/miR-4455 …
Expression profiling of the adhesion G protein-coupled receptor GPR133 (ADGRD1) in glioma subtypes.
Frenster JD, Kader M, Kamen S, Sun J, Chiriboga L, Serrano J, Bready D, Golub D, Ravn-Boess N, Stephan G, Chi AS, Kurz SC, Jain R, Park CY, Fenyo D, Liebscher I, Schöneberg T, Wiggin G, Newman R, Barnes M, Dickson JK, MacNeil DJ, Huang X, Shohdy N, Snuderl M, Zagzag D, Placantonakis DG. Frenster JD, et al. Neurooncol Adv. 2020 Apr 28;2(1):vdaa053. doi: 10.1093/noajnl/vdaa053. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32642706 Free PMC article.
We previously demonstrated that the adhesion G protein-coupled receptor GPR133 (ADGRD1) is necessary for tumor growth in adult glioblastoma, the most advanced malignancy within the glioma family. ...
We previously demonstrated that the adhesion G protein-coupled receptor GPR133 (ADGRD1) is necessary for tumor growth in adult gliobl …
Upregulation of mRNA Expression of ADGRD1/GPR133 and ADGRG7/GPR128 in SARS-CoV-2-Infected Lung Adenocarcinoma Calu-3 Cells.
Žáčková S, Pávová M, Trylčová J, Chalupová J, Priss A, Lukšan O, Weber J. Žáčková S, et al. Cells. 2024 May 7;13(10):791. doi: 10.3390/cells13100791. Cells. 2024. PMID: 38786015 Free PMC article.
Adhesion G protein-coupled receptors (aGPCRs) play an important role in neurodevelopment, immune defence and cancer; however, their role throughout viral infections is mostly unexplored. ...Based on significantly altered mRNA levels, we identified four aGPCR candidates-ADG …
Adhesion G protein-coupled receptors (aGPCRs) play an important role in neurodevelopment, immune defence and cancer; however, their r …
12 results