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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
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2009 14
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2011 21
2012 24
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2014 19
2015 12
2016 16
2017 18
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284 results

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Page 1
ADH1B: From alcoholism, natural selection, and cancer to the human phenome.
Polimanti R, Gelernter J. Polimanti R, et al. Am J Med Genet B Neuropsychiatr Genet. 2018 Mar;177(2):113-125. doi: 10.1002/ajmg.b.32523. Epub 2017 Mar 27. Am J Med Genet B Neuropsychiatr Genet. 2018. PMID: 28349588 Free PMC article. Review.
The ADH1B (Alcohol Dehydrogenase 1B (class I), Beta Polypeptide) gene and its best-known functional alleles, Arg48His (rs1229984, ADH1B*2) and Arg370Cys (rs2066702, ADH1B*3), have been investigated in relation to many phenotypic traits; most frequently includ …
The ADH1B (Alcohol Dehydrogenase 1B (class I), Beta Polypeptide) gene and its best-known functional alleles, Arg48His (rs1229984, …
ADH1B promotes mesothelial clearance and ovarian cancer infiltration.
Gharpure KM, Lara OD, Wen Y, Pradeep S, LaFargue C, Ivan C, Rupaimoole R, Hu W, Mangala LS, Wu SY, Nagaraja AS, Baggerly K, Sood AK. Gharpure KM, et al. Oncotarget. 2018 May 18;9(38):25115-25126. doi: 10.18632/oncotarget.25344. eCollection 2018 May 18. Oncotarget. 2018. PMID: 29861857 Free PMC article.
Moreover, gene array analysis revealed that ADH1B affects several pathways related to the migration and invasion of cancer cells. We also discovered that hypoxia increases ADH1B expression in ovarian cancer cells. Collectively, these findings indicate …
Moreover, gene array analysis revealed that ADH1B affects several pathways related to the migration and invasion of cancer cel …
Association between rs1229984 in ADH1B and cancer prevalence in a Japanese population.
Govind P, Pavethynath S, Sawabe M, Arai T, Muramatsu M. Govind P, et al. Mol Clin Oncol. 2020 Jun;12(6):503-510. doi: 10.3892/mco.2020.2021. Epub 2020 Mar 24. Mol Clin Oncol. 2020. PMID: 32337031 Free PMC article.
Associations between the ADH1B gene (alcohol dehydrogenase 1B), single nucleotide polymorphism (SNP) rs1229984 and cancer have been extensively studied yet evidence is inconsistent. ...In conclusion, there was no significant association between rs1229984 and odds of …
Associations between the ADH1B gene (alcohol dehydrogenase 1B), single nucleotide polymorphism (SNP) rs1229984 and cancer have …
Association of ADH1B Arg47His polymorphism with the risk of cancer: a meta-analysis.
Tan B, Ning N. Tan B, et al. Biosci Rep. 2019 Apr 2;39(4):BSR20181915. doi: 10.1042/BSR20181915. Print 2019 Apr 30. Biosci Rep. 2019. PMID: 30872408 Free PMC article.
Stratified analysis by cancer type and ethnicity showed that a decreased risk was associated with esophageal cancer and head and neck cancer amongst Asians. In conclusion, our meta-analysis suggested that ADH1B Arg47His polymorphism was significantly a …
Stratified analysis by cancer type and ethnicity showed that a decreased risk was associated with esophageal cancer and head a …
Folate, alcohol, ADH1B and ALDH2 and colorectal cancer risk.
Seol JE, Kim J, Lee BH, Hwang DY, Jeong J, Lee HJ, Ahn YO, Lee JE, Kim DH. Seol JE, et al. Public Health Nutr. 2020 Mar 30:1-8. doi: 10.1017/S136898001900452X. Online ahead of print. Public Health Nutr. 2020. PMID: 32223781
OBJECTIVE: There is limited evidence on the interaction by alcohol dehydrogenase 2 (ADH1B) (rs1229984) and aldehyde dehydrogenase 2 (ALDH2) (rs671) regarding the associations of alcohol and a methyl diet (low folate and high alcohol intake) with cancer risk, partly …
OBJECTIVE: There is limited evidence on the interaction by alcohol dehydrogenase 2 (ADH1B) (rs1229984) and aldehyde dehydrogenase 2 ( …
Impacts of ADH1B rs1229984 and ALDH2 rs671 polymorphisms on risks of alcohol-related disorder and cancer.
Chang TG, Yen TT, Wei CY, Hsiao TH, Chen IC. Chang TG, et al. Cancer Med. 2023 Jan;12(1):747-759. doi: 10.1002/cam4.4920. Epub 2022 Jun 6. Cancer Med. 2023. PMID: 35670037 Free PMC article.

The CC genotype of ADH1B rs1229984 was significantly associated with cancer of the larynx, pharynx, and nasal cavities [odds ratio (OR) = 1.56, p = 0.0009], cancer of the pancreas (OR = 1.66, p = 0.018), and cancer of the esophagus (OR = 4.10, p < 0

…
The CC genotype of ADH1B rs1229984 was significantly associated with cancer of the larynx, pharynx, and nasal cavities [odds r …
The Roles of Drug Metabolism-Related ADH1B in Immune Regulation and Therapeutic Response of Ovarian Cancer.
Xu Z, Peng B, Kang F, Zhang W, Xiao M, Li J, Hong Q, Cai Y, Liu W, Yan Y, Peng J. Xu Z, et al. Front Cell Dev Biol. 2022 Jun 9;10:877254. doi: 10.3389/fcell.2022.877254. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35756990 Free PMC article.
Emerging studies have realized the importance of drug metabolism-related genes in the treatment and prognosis of cancers, including ovarian cancer (OV). In this study, using comprehensive bioinformatics and western blot, we identified that the drug metabolism-relate …
Emerging studies have realized the importance of drug metabolism-related genes in the treatment and prognosis of cancers, including o …
Cancer-associated fibroblasts in early-stage lung adenocarcinoma correlate with tumor aggressiveness.
Vasiukov G, Zou Y, Senosain MF, Rahman JSM, Antic S, Young KM, Grogan EL, Kammer MN, Maldonado F, Reinhart-King CA, Massion PP. Vasiukov G, et al. Sci Rep. 2023 Oct 17;13(1):17604. doi: 10.1038/s41598-023-43296-3. Sci Rep. 2023. PMID: 37848457 Free PMC article.
Lung adenocarcinoma (LUAD) is the predominant type of lung cancer in the U.S. and exhibits a broad variety of behaviors ranging from indolent to aggressive. ...Single-cell RNA sequencing and histological assessment showed that aggressive LUADs are characterized by a decrea …
Lung adenocarcinoma (LUAD) is the predominant type of lung cancer in the U.S. and exhibits a broad variety of behaviors ranging from …
Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma.
Zhou Y, Yu L, Huang P, Zhao X, He R, Cui Y, Pan B, Liu C. Zhou Y, et al. Front Pharmacol. 2023 May 9;14:1166454. doi: 10.3389/fphar.2023.1166454. eCollection 2023. Front Pharmacol. 2023. PMID: 37229243 Free PMC article.
The expression of ADH1B was distinctly downregulated in tumor tissues of pan-cancer. The expression of ADH1B was negatively correlated with ADH1B methylation. Small-molecule drugs panobinostat, oxaliplatin, ixabepilone, and seliciclib were significantl …
The expression of ADH1B was distinctly downregulated in tumor tissues of pan-cancer. The expression of ADH1B was negati …
Alcohol intake, ADH1B and ADH1C genotypes, and the risk of colorectal cancer by sex and subsite in the Netherlands Cohort Study.
Offermans NSM, Ketcham SM, van den Brandt PA, Weijenberg MP, Simons CCJM. Offermans NSM, et al. Carcinogenesis. 2018 Mar 8;39(3):375-388. doi: 10.1093/carcin/bgy011. Carcinogenesis. 2018. PMID: 29390059
The alcohol-colorectal cancer (CRC) association may differ by sex and ADH1B and ADH1C genotypes. ...Alcohol intake increased CRC risk in both sexes, though in women only in the (proximal) colon when in excess of 30 g/day. In male drinkers, ADH1B rs4147536 inc …
The alcohol-colorectal cancer (CRC) association may differ by sex and ADH1B and ADH1C genotypes. ...Alcohol intake increased C …
284 results