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2010 2
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2014 11
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Inhibiting the stringent response blocks Mycobacterium tuberculosis entry into quiescence and reduces persistence.
Dutta NK, Klinkenberg LG, Vazquez MJ, Segura-Carro D, Colmenarejo G, Ramon F, Rodriguez-Miquel B, Mata-Cantero L, Porras-De Francisco E, Chuang YM, Rubin H, Lee JJ, Eoh H, Bader JS, Perez-Herran E, Mendoza-Losana A, Karakousis PC. Dutta NK, et al. Sci Adv. 2019 Mar 20;5(3):eaav2104. doi: 10.1126/sciadv.aav2104. eCollection 2019 Mar. Sci Adv. 2019. PMID: 30906866 Free PMC article.
Unprecedented in Vitro Antitubercular Activitiy of Manganese(II) Complexes Containing 1,10-Phenanthroline and Dicarboxylate Ligands: Increased Activity, Superior Selectivity, and Lower Toxicity in Comparison to Their Copper(II) Analogs.
McCarron P, McCann M, Devereux M, Kavanagh K, Skerry C, Karakousis PC, Aor AC, Mello TP, Santos ALS, Campos DL, Pavan FR. McCarron P, et al. Front Microbiol. 2018 Jul 2;9:1432. doi: 10.3389/fmicb.2018.01432. eCollection 2018. Front Microbiol. 2018. PMID: 30013535 Free PMC article.
Host-Mediated Bioactivation of Pyrazinamide: Implications for Efficacy, Resistance, and Therapeutic Alternatives.
Via LE, Savic R, Weiner DM, Zimmerman MD, Prideaux B, Irwin SM, Lyon E, O'Brien P, Gopal P, Eum S, Lee M, Lanoix JP, Dutta NK, Shim T, Cho JS, Kim W, Karakousis PC, Lenaerts A, Nuermberger E, Barry CE 3rd, Dartois V. Via LE, et al. ACS Infect Dis. 2015 May 8;1(5):203-214. doi: 10.1021/id500028m. ACS Infect Dis. 2015. PMID: 26086040 Free PMC article.
Future target-based drug discovery for tuberculosis?
Kana BD, Karakousis PC, Parish T, Dick T. Kana BD, et al. Tuberculosis (Edinb). 2014 Dec;94(6):551-6. doi: 10.1016/j.tube.2014.10.003. Tuberculosis (Edinb). 2014. PMID: 25458615 Free PMC article. Review.
31 results