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Comprehensive analysis of alternative splicing across multiple transcriptomic cohorts reveals prognostic signatures in prostate cancer.
Mou Z, Spencer J, McGrath JS, Harries LW. Mou Z, et al. Hum Genomics. 2023 Nov 3;17(1):97. doi: 10.1186/s40246-023-00545-w. Hum Genomics. 2023. PMID: 37924098 Free PMC article.
BACKGROUND: Alternative splicing (AS) plays a crucial role in transcriptomic diversity and is a hallmark of cancer that profoundly influences the development and progression of prostate cancer (PCa), a prevalent and potentially life-limiting cancer among men. …
BACKGROUND: Alternative splicing (AS) plays a crucial role in transcriptomic diversity and is a hallmark of cancer that profoundly in …
Efficacy and safety of a triple combination of atezolizumab, bevacizumab plus GEMOX for advanced biliary tract cancer: a multicenter, single-arm, retrospective study.
Wang K, Liu ZH, Yu HM, Cheng YQ, Xiang YJ, Zhong JY, Ni QZ, Zhou LP, Liang C, Zhou HK, Pan WW, Guo WX, Shi J, Cheng SQ. Wang K, et al. Therap Adv Gastroenterol. 2023 Mar 28;16:17562848231160630. doi: 10.1177/17562848231160630. eCollection 2023. Therap Adv Gastroenterol. 2023. PMID: 37007215 Free PMC article.
Furthermore, fever (73.3%), neutropenia (63.3%), increased aspartate transaminase and alanine aminotransferase levels (50.0% and 43.3%, respectively) are the most common TRAEs. Bioinformatics analysis revealed patients with altered ALS2CL had a higher ORR. CONCLUSION: The …
Furthermore, fever (73.3%), neutropenia (63.3%), increased aspartate transaminase and alanine aminotransferase levels (50.0% and 43.3%, resp …
Multiple tumor-suppressor genes on chromosome 3p contribute to head and neck squamous cell carcinoma tumorigenesis.
Lee DJ, Schönleben F, Banuchi VE, Qiu W, Close LG, Assaad AM, Su GH. Lee DJ, et al. Cancer Biol Ther. 2010 Oct 1;10(7):689-93. doi: 10.4161/cbt.10.7.12886. Epub 2010 Oct 1. Cancer Biol Ther. 2010. PMID: 20657180 Free PMC article.
Recently, one systematic study of genomic sequencing was performed on breast and colorectal cancers and 189 candidate cancer genes (CAN-genes) were reported. ...The mutations appeared hemizygous and SNP array analyses showed that these missense mutations are accompa …
Recently, one systematic study of genomic sequencing was performed on breast and colorectal cancers and 189 candidate cancer g …