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The following terms were not found in PubMed: ARTICLETpz1TPP1prevents, andprotects, Stn1-Ten1complex, infission
Page 1
Tpz1(TPP1) prevents telomerase activation and protects telomeres by modulating the Stn1-Ten1 complex in fission yeast.
Mennie AK, Moser BA, Hoyle A, Low RS, Tanaka K, Nakamura TM. Mennie AK, et al. Commun Biol. 2019 Aug 7;2:297. doi: 10.1038/s42003-019-0546-8. eCollection 2019. Commun Biol. 2019. PMID: 31396577 Free PMC article.
The SWSSS motif works redundantly with Lys242 SUMOylation to promote binding of Stn1-Ten1 at telomere and sub-telomere regions to protect against single-strand annealing (SSA)-dependent telomere fusions, and to prevent telomerase accumulation at tel …
The SWSSS motif works redundantly with Lys242 SUMOylation to promote binding of Stn1-Ten1 at telomere and sub-telomere regions …
Characterization of the telomerase modulating activities of yeast DNA helicases.
Nickens DG, Bochman ML. Nickens DG, et al. Methods Enzymol. 2021;661:327-342. doi: 10.1016/bs.mie.2021.08.005. Epub 2021 Sep 6. Methods Enzymol. 2021. PMID: 34776218 Free PMC article.
Thus, the regulation of telomerase is critical for normal telomere homeostasis. Of the various known ways that telomerase activity is modulated in vivo, recent studies have demonstrated that DNA helicases are involved. In Saccharomyces …
Thus, the regulation of telomerase is critical for normal telomere homeostasis. Of the various known ways that telomerase …
How telomerase reaches its end: mechanism of telomerase regulation by the telomeric complex.
Bianchi A, Shore D. Bianchi A, et al. Mol Cell. 2008 Jul 25;31(2):153-65. doi: 10.1016/j.molcel.2008.06.013. Mol Cell. 2008. PMID: 18657499 Free article. Review.
The telomerase enzyme, which synthesizes telomeric DNA repeats, is regulated in cis at individual chromosome ends by the telomeric protein/DNA complex in a manner dependent on telomere repeat-array length. A dynamic interplay between telomerase- …
The telomerase enzyme, which synthesizes telomeric DNA repeats, is regulated in cis at individual chromosome ends by the te …
Fission yeast Ccq1 is a modulator of telomerase activity.
Armstrong CA, Moiseeva V, Collopy LC, Pearson SR, Ullah TR, Xi ST, Martin J, Subramaniam S, Marelli S, Amelina H, Tomita K. Armstrong CA, et al. Nucleic Acids Res. 2018 Jan 25;46(2):704-716. doi: 10.1093/nar/gkx1223. Nucleic Acids Res. 2018. PMID: 29216371 Free PMC article.
In fission yeast, telomerase is recruited to chromosome ends by the shelterin component Tpz1 and its binding partner Ccq1, where telomerase binds to the 3' overhang to add telomeric repeats. ...The Clr4 complex also has a negative regulation activit …
In fission yeast, telomerase is recruited to chromosome ends by the shelterin component Tpz1 and its binding partner Ccq1, whe …
Modulation of yeast telomerase activity by Cdc13 and Est1 in vitro.
Chen YF, Lu CY, Lin YC, Yu TY, Chang CP, Li JR, Li HW, Lin JJ. Chen YF, et al. Sci Rep. 2016 Sep 23;6:34104. doi: 10.1038/srep34104. Sci Rep. 2016. PMID: 27659693 Free PMC article.
Telomerase is the enzyme involved in extending telomeric DNA. Control of telomerase activity by modulating its access to chromosome ends is one of the most important fundamental mechanisms. This study established an in vitro yeast telo …
Telomerase is the enzyme involved in extending telomeric DNA. Control of telomerase activity by modulating …
A subtelomeric region affects telomerase-negative replicative senescence in Saccharomyces cerevisiae.
Jolivet P, Serhal K, Graf M, Eberhard S, Xu Z, Luke B, Teixeira MT. Jolivet P, et al. Sci Rep. 2019 Feb 12;9(1):1845. doi: 10.1038/s41598-018-38000-9. Sci Rep. 2019. PMID: 30755624 Free PMC article.
In Saccharomyces cerevisiae, senescence is mainly dictated by the first telomere that reaches a critically short length, activating a DNA-damage-like response. How the corresponding signaling is modulated by the telomeric structure and co …
In Saccharomyces cerevisiae, senescence is mainly dictated by the first telomere that reaches a critically short length …
Polypeptide components of telomere nucleoprotein complex.
Kuimov AN. Kuimov AN. Biochemistry (Mosc). 2004 Feb;69(2):117-29. doi: 10.1023/b:biry.0000018941.81962.1c. Biochemistry (Mosc). 2004. PMID: 15000677 Review.
Increase in TERF1 concentration prevents telomere elongation by telomerase. Decrease in TERF2 concentration (preventing t-loop formation) is accompanied by blockade of proliferation and appearance of other signs of cellular senescence in experiments. Natural regulat …
Increase in TERF1 concentration prevents telomere elongation by telomerase. Decrease in TERF2 concentration (preventing t-loop …
The Saccharomyces cerevisiae Hrq1 and Pif1 DNA helicases synergistically modulate telomerase activity in vitro.
Nickens DG, Rogers CM, Bochman ML. Nickens DG, et al. J Biol Chem. 2018 Sep 14;293(37):14481-14496. doi: 10.1074/jbc.RA118.004092. Epub 2018 Aug 1. J Biol Chem. 2018. PMID: 30068549 Free PMC article.
The Saccharomyces cerevisiae Pif1 helicase was the first discovered catalytic inhibitor of telomerase, but recent experimental evidence suggests that Hrq1, the yeast homolog of the disease-linked human RecQ-like helicase 4 (RECQL4), plays a similar rol …
The Saccharomyces cerevisiae Pif1 helicase was the first discovered catalytic inhibitor of telomerase, but recent exper …
Drosophila telomeres: an exception providing new insights.
Mason JM, Frydrychova RC, Biessmann H. Mason JM, et al. Bioessays. 2008 Jan;30(1):25-37. doi: 10.1002/bies.20688. Bioessays. 2008. PMID: 18081009 Free PMC article. Review.
Telomere functions, however, are similar to those found in telomerase-based telomeres, even though the underlying mechanisms may differ. ...Maintaining and regulating the transcriptional activity of the telomeric retrotransposons in Drosophila r …
Telomere functions, however, are similar to those found in telomerase-based telomeres, even though the underlying mecha …
Cell populations can use aneuploidy to survive telomerase insufficiency.
Millet C, Ausiannikava D, Le Bihan T, Granneman S, Makovets S. Millet C, et al. Nat Commun. 2015 Oct 22;6:8664. doi: 10.1038/ncomms9664. Nat Commun. 2015. PMID: 26489519 Free PMC article.
Telomerase maintains ends of eukaryotic chromosomes, telomeres. Telomerase loss results in replicative senescence and a switch to recombination-dependent telomere maintenance. ...In yeast grown at elevated temperatures, telomerase acti …
Telomerase maintains ends of eukaryotic chromosomes, telomeres. Telomerase loss results in replicative senescence and a …
32 results