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Circ_ATAD3B inhibits cell proliferation of breast cancer via mediating the miR-570-3p/MX2 axis.
Song B, Xu C, Zhang Y, Shan Y. Song B, et al. Prev Med. 2023 Aug;173:107568. doi: 10.1016/j.ypmed.2023.107568. Epub 2023 Jun 5. Prev Med. 2023. PMID: 37286092 Free article.
The tumor suppressor circ_ATAD3B prevents cancer progression by regulating the miR-570-3p/MX2 pathway. Circ_ATAD3B may be a candidate for targeted therapy of breast cancer....
The tumor suppressor circ_ATAD3B prevents cancer progression by regulating the miR-570-3p/MX2 pathway. Circ_ATAD3B may …
ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A.
Merle N, Féraud O, Gilquin B, Hubstenberger A, Kieffer-Jacquinot S, Assard N, Bennaceur-Griscelli A, Honnorat J, Baudier J. Merle N, et al. Mitochondrion. 2012 Jul;12(4):441-8. doi: 10.1016/j.mito.2012.05.005. Epub 2012 Jun 2. Mitochondrion. 2012. PMID: 22664726
Here we report on the identification of a human pluripotent embryonic stem cell (hESC) specific mitochondrial protein that is re-expressed in cancer cells, ATAD3B. ATAD3B belongs to the AAA+ ATPase ATAD3 protein family of mitochondrial proteins specific to mu …
Here we report on the identification of a human pluripotent embryonic stem cell (hESC) specific mitochondrial protein that is re-expressed i …
ATAD3, a vital membrane bound mitochondrial ATPase involved in tumor progression.
Li S, Rousseau D. Li S, et al. J Bioenerg Biomembr. 2012 Feb;44(1):189-97. doi: 10.1007/s10863-012-9424-5. J Bioenerg Biomembr. 2012. PMID: 22318359 Review.
In primates and human, two other genes have appeared (called ATAD3B and ATAD3C versus ATAD3A the ancestral gene). ATAD3 knock-down in different non-transformed cell lines is associated with drastic changes in the mitochondrial network, inhibition of proliferation and modif …
In primates and human, two other genes have appeared (called ATAD3B and ATAD3C versus ATAD3A the ancestral gene). ATAD3 knock-down in …
Integrative analysis of deep sequencing data identifies estrogen receptor early response genes and links ATAD3B to poor survival in breast cancer.
Ovaska K, Matarese F, Grote K, Charapitsa I, Cervera A, Liu C, Reid G, Seifert M, Stunnenberg HG, Hautaniemi S. Ovaska K, et al. PLoS Comput Biol. 2013;9(6):e1003100. doi: 10.1371/journal.pcbi.1003100. Epub 2013 Jun 20. PLoS Comput Biol. 2013. PMID: 23818839 Free PMC article.
To demonstrate the SPINLONG approach, we analyzed ChIP-seq data reporting PolII, estrogen receptor alpha (ERalpha), H3K4me3 and H2A.Z occupancy at five time points in the MCF-7 breast cancer cell line after estradiol stimulus. We obtained 777 ERa early responsive genes and …
To demonstrate the SPINLONG approach, we analyzed ChIP-seq data reporting PolII, estrogen receptor alpha (ERalpha), H3K4me3 and H2A.Z occupa …
Prognostic value of ATAD3 gene cluster expression in hepatocellular carcinoma.
Liu X, Li G, Ai L, Ye Q, Yu T, Yang B. Liu X, et al. Oncol Lett. 2019 Aug;18(2):1304-1310. doi: 10.3892/ol.2019.10454. Epub 2019 Jun 7. Oncol Lett. 2019. PMID: 31423190 Free PMC article.
ATAD3A and ATAD3B expression levels were higher in HCC compared with normal liver tissues (P<0.05). ...In conclusion, ATAD3A and ATAD3B may serve as potential prognostic biomarkers for patients with HCC....
ATAD3A and ATAD3B expression levels were higher in HCC compared with normal liver tissues (P<0.05). ...In conclusion, ATAD3A and …
Differentially Expressed Mitochondrial Proteins in Human MCF7 Breast Cancer Cells Resistant to Paclitaxel.
Daniel P, Halada P, Jelínek M, Balušíková K, Kovář J. Daniel P, et al. Int J Mol Sci. 2019 Jun 19;20(12):2986. doi: 10.3390/ijms20122986. Int J Mol Sci. 2019. PMID: 31248089 Free PMC article.
Identification of novel proteins with changed expression in resistant cancer cells could be helpful in elucidation mechanisms involved in the development of acquired resistance to paclitaxel. ...To summarize, we identified several novel proteins of a mitochondrial fraction …
Identification of novel proteins with changed expression in resistant cancer cells could be helpful in elucidation mechanisms involve …
Whole-exome sequencing identifies prognostic mutational signatures in gastric cancer.
Zhu Z, Fu H, Wang S, Yu X, You Q, Shi M, Dai C, Wang G, Cha W, Wang W. Zhu Z, et al. Ann Transl Med. 2020 Nov;8(22):1484. doi: 10.21037/atm-20-6620. Ann Transl Med. 2020. PMID: 33313229 Free PMC article.
BACKGROUND: Gastric cancer (GC) is a heterogeneous disease, and is a leading cause of cancer deaths in Eastern Asia. ...RESULTS: A number of significantly mutated genes in somatic and germline cells were identified. Among them, ATAD3B somatic mutation, a pote …
BACKGROUND: Gastric cancer (GC) is a heterogeneous disease, and is a leading cause of cancer deaths in Eastern Asia. ...RESULT …
[ATAD3, a vital membrane-bound mitochondrial ATPase involved in tumor progression].
Li S, Rousseau D. Li S, et al. Med Sci (Paris). 2011 Dec;27(12):1089-95. doi: 10.1051/medsci/20112712015. Epub 2011 Dec 23. Med Sci (Paris). 2011. PMID: 22192748 Free article. Review. French.
In primates and humans, two other genes have appeared (called ATAD3B and ATAD3C versus ATAD3A the ancestral gene). ATAD3 knock down in different non-transformed cell lines is associated with drastic changes in the mitochondrial network, inhibition of proliferation and modi …
In primates and humans, two other genes have appeared (called ATAD3B and ATAD3C versus ATAD3A the ancestral gene). ATAD3 knock down i …
Pharmacogenomics of in vitro response of the NCI-60 cancer cell line panel to Indian natural products.
Sankaran H, Negi S, McShane LM, Zhao Y, Krushkal J. Sankaran H, et al. BMC Cancer. 2022 May 7;22(1):512. doi: 10.1186/s12885-022-09580-7. BMC Cancer. 2022. PMID: 35525914 Free PMC article.
We analyzed expression measures for annotated transcripts, lncRNAs, and miRNAs, and protein-changing single nucleotide variants in cancer-related genes. We also examined the similarities between cancer cell line response to Indian natural products and response to re …
We analyzed expression measures for annotated transcripts, lncRNAs, and miRNAs, and protein-changing single nucleotide variants in cancer …
Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer Networks.
Ghanat Bari M, Ung CY, Zhang C, Zhu S, Li H. Ghanat Bari M, et al. Sci Rep. 2017 Aug 1;7(1):6993. doi: 10.1038/s41598-017-07481-5. Sci Rep. 2017. PMID: 28765560 Free PMC article.
Given this hypothesis, we developed a Machine Learning-Assisted Network Inference (MALANI) algorithm, which assesses all genes regardless of expression or mutational status in the context of cancer etiology. We used 8807 expression arrays, corresponding to 9 cancer …
Given this hypothesis, we developed a Machine Learning-Assisted Network Inference (MALANI) algorithm, which assesses all genes regardless of …
14 results