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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
2006 3
2007 11
2008 12
2009 9
2010 27
2011 29
2012 49
2013 65
2014 67
2015 80
2016 93
2017 97
2018 106
2019 111
2020 116
2021 99
2022 95
2023 62
2024 43

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1,032 results

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Page 1
Autophagic Schwann cells promote perineural invasion mediated by the NGF/ATG7 paracrine pathway in pancreatic cancer.
Zhang W, He R, Yang W, Zhang Y, Yuan Q, Wang J, Liu Y, Chen S, Zhang S, Zhang W, Zhu Z, Zhang J, Wang Z, Li J. Zhang W, et al. J Exp Clin Cancer Res. 2022 Feb 2;41(1):48. doi: 10.1186/s13046-021-02198-w. J Exp Clin Cancer Res. 2022. PMID: 35109895 Free PMC article.
METHODS: To investigate the autophagy of Schwann cells (SCs) in PNI, we reproduced the microenvironment of PNI by collecting clinical PNI tissue, performing sciatic nerve injection of nude mice with cancer cells and establishing a Dorsal root ganglion (DRG) coculture syste …
METHODS: To investigate the autophagy of Schwann cells (SCs) in PNI, we reproduced the microenvironment of PNI by collecting clinical PNI ti …
Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway.
Zhou J, Jiang YY, Chen H, Wu YC, Zhang L. Zhou J, et al. Cell Prolif. 2020 Feb;53(2):e12739. doi: 10.1111/cpr.12739. Epub 2019 Dec 9. Cell Prolif. 2020. PMID: 31820522 Free PMC article.
It has been shown that Tan-I exhibited anti-tumour activities on different types of cancers. However, the underlying mechanisms by which Tan- regulates apoptosis and autophagy in ovarian cancer remain unclear. ...In additional, Tan- induced cancer cell apopto …
It has been shown that Tan-I exhibited anti-tumour activities on different types of cancers. However, the underlying mechanisms by wh …
Autophagy in the physiological endometrium and cancer.
Devis-Jauregui L, Eritja N, Davis ML, Matias-Guiu X, Llobet-Navàs D. Devis-Jauregui L, et al. Autophagy. 2021 May;17(5):1077-1095. doi: 10.1080/15548627.2020.1752548. Epub 2020 May 13. Autophagy. 2021. PMID: 32401642 Free PMC article. Review.
The current review highlights the most recent findings regarding the process of autophagy in the normal and cancerous endometrial tissue. Current research efforts aiming to therapeutically exploit autophagy and the methodological approaches used are discussed.Abbreviations …
The current review highlights the most recent findings regarding the process of autophagy in the normal and cancerous endometrial tis …
Autophagy promotes ferroptosis by degradation of ferritin.
Hou W, Xie Y, Song X, Sun X, Lotze MT, Zeh HJ 3rd, Kang R, Tang D. Hou W, et al. Autophagy. 2016 Aug 2;12(8):1425-8. doi: 10.1080/15548627.2016.1187366. Epub 2016 May 31. Autophagy. 2016. PMID: 27245739 Free PMC article.
Here, we demonstrated that autophagy contributes to ferroptosis by degradation of ferritin in fibroblasts and cancer cells. Knockout or knockdown of Atg5 (autophagy-related 5) and Atg7 limited erastin-induced ferroptosis with decreased intracellular ferrous iron lev …
Here, we demonstrated that autophagy contributes to ferroptosis by degradation of ferritin in fibroblasts and cancer cells. Knockout …
Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy.
Wang K, Fu S, Dong L, Zhang D, Wang M, Wu X, Shen E, Luo L, Li C, Nice EC, Huang C, Zou B. Wang K, et al. Autophagy. 2023 Dec;19(12):3132-3150. doi: 10.1080/15548627.2023.2239042. Epub 2023 Jul 23. Autophagy. 2023. PMID: 37471054
Colorectal cancer (CRC) is one of the most common malignancies worldwide and remains a major clinical challenge. ...Taken together, our results reveal a novel link between periplocin and the lysophagy machinery, and indicate periplocin as a potential therapeutic option for …
Colorectal cancer (CRC) is one of the most common malignancies worldwide and remains a major clinical challenge. ...Taken together, o …
Quercetin induces p53-independent cancer cell death through lysosome activation by the transcription factor EB and Reactive Oxygen Species-dependent ferroptosis.
Wang ZX, Ma J, Li XY, Wu Y, Shi H, Chen Y, Lu G, Shen HM, Lu GD, Zhou J. Wang ZX, et al. Br J Pharmacol. 2021 Mar;178(5):1133-1148. doi: 10.1111/bph.15350. Epub 2021 Feb 2. Br J Pharmacol. 2021. PMID: 33347603 Free article.
Quercetin exerts anti-cancer effects, but the underlying molecular mechanism is largely unknown. ...KEY RESULTS: Quercetin is known to promote p53-independent cell death in various cancer cell lines. Although quercetin induces autophagy, genetic silencing of Atg7 …
Quercetin exerts anti-cancer effects, but the underlying molecular mechanism is largely unknown. ...KEY RESULTS: Quercetin is known t …
Celastrol upregulated ATG7 triggers autophagy via targeting Nur77 in colorectal cancer.
Zhang W, Wu Z, Qi H, Chen L, Wang T, Mao X, Shi H, Chen H, Zhong M, Shi X, Wang X, Li Q. Zhang W, et al. Phytomedicine. 2022 Sep;104:154280. doi: 10.1016/j.phymed.2022.154280. Epub 2022 Jun 16. Phytomedicine. 2022. PMID: 35752079
Celastrol induced autophagy and the autophagy inhibition enhanced the anti-CRC effects. The ATG7 was up-regulated obviously after celastrol treatment for Nur77 overexpressing CRC cancer cells. ...Celastrol exerted anti-CRC effects by inhibiting Nur77 to induce high …
Celastrol induced autophagy and the autophagy inhibition enhanced the anti-CRC effects. The ATG7 was up-regulated obviously after cel …
Autophagy-associated circRNA circCDYL augments autophagy and promotes breast cancer progression.
Liang G, Ling Y, Mehrpour M, Saw PE, Liu Z, Tan W, Tian Z, Zhong W, Lin W, Luo Q, Lin Q, Li Q, Zhou Y, Hamai A, Codogno P, Li J, Song E, Gong C. Liang G, et al. Mol Cancer. 2020 Mar 25;19(1):65. doi: 10.1186/s12943-020-01152-2. Mol Cancer. 2020. PMID: 32213200 Free PMC article.
RESULTS: An autophagy associated circRNA circCDYL was elevated by 3.2 folds in BC tissues as compared with the adjacent non-cancerous tissues, and circCDYL promoted autophagic level in BC cells via the miR-1275-ATG7/ULK1 axis; Moreover, circCDYL enhanced the maligna …
RESULTS: An autophagy associated circRNA circCDYL was elevated by 3.2 folds in BC tissues as compared with the adjacent non-cancerous …
JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice.
Song X, Zhu S, Xie Y, Liu J, Sun L, Zeng D, Wang P, Ma X, Kroemer G, Bartlett DL, Billiar TR, Lotze MT, Zeh HJ, Kang R, Tang D. Song X, et al. Gastroenterology. 2018 Apr;154(5):1480-1493. doi: 10.1053/j.gastro.2017.12.004. Epub 2017 Dec 14. Gastroenterology. 2018. PMID: 29248440 Free PMC article.
In analyses of Cancer Genome Atlas data and tissue microarrays, we associated increased tumor level of CA9 mRNA or protein with shorter survival times of patients with pancreatic, kidney, or lung cancers. ...JTC801 might be developed for treatment of pancreatic c …
In analyses of Cancer Genome Atlas data and tissue microarrays, we associated increased tumor level of CA9 mRNA or protein with short …
TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/beta-catenin degradation and is targeted for GSK3B/GSK3beta-mediated phosphorylation and degradation.
Wu H, Lu XX, Wang JR, Yang TY, Li XM, He XS, Li Y, Ye WL, Wu Y, Gan WJ, Guo PD, Li JM. Wu H, et al. Autophagy. 2019 Sep;15(9):1506-1522. doi: 10.1080/15548627.2019.1586250. Epub 2019 Mar 4. Autophagy. 2019. PMID: 30806153 Free PMC article.
Aberrant CTNNB1 signaling is one of the fundamental processes in cancers, especially colorectal cancer (CRC). Here, we reported that TRAF6, an E3 ubiquitin ligase important for inflammatory signaling, inhibited epithelial-mesenchymal transition (EMT) and CRC metasta …
Aberrant CTNNB1 signaling is one of the fundamental processes in cancers, especially colorectal cancer (CRC). Here, we reporte …
1,032 results