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ATP13A4 Upregulation Drives the Elevated Polyamine Transport System in the Breast Cancer Cell Line MCF7.
van Veen S, Kourti A, Ausloos E, Van Asselberghs J, Van den Haute C, Baekelandt V, Eggermont J, Vangheluwe P. van Veen S, et al. Biomolecules. 2023 May 31;13(6):918. doi: 10.3390/biom13060918. Biomolecules. 2023. PMID: 37371498 Free PMC article.
Thus far, the polyamine transporters contributing to the elevated levels of polyamines in cancer cells have not yet been described, despite the fact that polyamine transport inhibitors are considered for cancer therapy. ...In conclusion, we established ATP13A4 …
Thus far, the polyamine transporters contributing to the elevated levels of polyamines in cancer cells have not yet been described, d …
Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition.
Davis SJ, Sheppard KE, Anglesio MS, George J, Traficante N, Fereday S, Intermaggio MP, Menon U, Gentry-Maharaj A, Lubinski J, Gronwald J, Pearce CL, Pike MC, Wu A, Kommoss S, Pfisterer J, du Bois A, Hilpert F, Ramus SJ, Bowtell DD, Huntsman DG, Pearson RB, Simpson KJ, Campbell IG, Gorringe KL. Davis SJ, et al. Mol Cancer Ther. 2015 Jun;14(6):1495-503. doi: 10.1158/1535-7163.MCT-15-0039. Epub 2015 Apr 7. Mol Cancer Ther. 2015. PMID: 25852062
The Australian Ovarian Cancer Study and The Cancer Genome Atlas datasets were also used to assess the correlation between gene expression, patient survival, and tumor classification. In a multivariate analysis, high GAB2 expression was associated with improved overa …
The Australian Ovarian Cancer Study and The Cancer Genome Atlas datasets were also used to assess the correlation between gene …
Identification of Key Genes With Differential Correlations in Lung Adenocarcinoma.
Zhou Y, Xu B, Zhou Y, Liu J, Zheng X, Liu Y, Deng H, Liu M, Ren X, Xia J, Kong X, Huang T, Jiang J. Zhou Y, et al. Front Cell Dev Biol. 2021 May 5;9:675438. doi: 10.3389/fcell.2021.675438. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34026765 Free PMC article.
Finally, dozens of novel genes with opposite correlations including ATP13A4-AS1, HIGD1B, DAP3, and ISG20L2 were identified. Further biological and survival analyses highlighted their potential values in the diagnosis and treatment of LUAD. Moreover, real-time qPCR confirme …
Finally, dozens of novel genes with opposite correlations including ATP13A4-AS1, HIGD1B, DAP3, and ISG20L2 were identified. Further b …
Coexisting of COX7A2L-ALK, LINC01210-ALK, ATP13A4-ALK and Acquired SLCO2A1-ALK in a Lung Adenocarcinoma with Rearrangements Loss During the Treatment of Crizotinib and Ceritinib: A Case Report.
Cai C, Long Y, Li Y, Huang M. Cai C, et al. Onco Targets Ther. 2020 Aug 20;13:8313-8316. doi: 10.2147/OTT.S258067. eCollection 2020. Onco Targets Ther. 2020. PMID: 32903930 Free PMC article.
ALK rearrangements account for ~5% of non-small-cell lung cancer (NSCLC). Numerous rearrangement partners have been discovered. ...Sequential ceritinib resulted in further 8 months of PFS, after which NGS results demonstrated the loss of ATP13A4-ALK and SLCO2A1-ALK. …
ALK rearrangements account for ~5% of non-small-cell lung cancer (NSCLC). Numerous rearrangement partners have been discovered. ...Se …