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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2005 2
2006 2
2008 3
2009 4
2010 2
2011 2
2012 1
2013 7
2014 9
2015 23
2016 21
2017 12
2018 17
2019 7
2020 11
2021 14
2022 14
2023 14
2024 7

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158 results

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Page 1
Functional Analysis and Clinical Importance of ATP1A1 in Colon Cancer.
Sumiyoshi S, Shiozaki A, Kosuga T, Simizu H, Kudo M, Kiuchi J, Arita T, Konishi H, Komatsu S, Kuriu Y, Kubota T, Fujiwara H, Morinaga Y, Konishi E, Otsuji E. Sumiyoshi S, et al. Ann Surg Oncol. 2023 Oct;30(11):6898-6910. doi: 10.1245/s10434-023-13779-8. Epub 2023 Jul 5. Ann Surg Oncol. 2023. PMID: 37407874
BACKGROUND: Na(+)/K(+)-ATPase alpha1 subunit (ATP1A1) exhibits aberrant expression in various types of cancer. Moreover, its levels in specific tissues are associated with the development of cancer. Nevertheless, the mechanism and signaling pathways underlyin …
BACKGROUND: Na(+)/K(+)-ATPase alpha1 subunit (ATP1A1) exhibits aberrant expression in various types of cancer. Moreover, its l …
Telomere-related gene risk model for prognosis and drug treatment efficiency prediction in kidney cancer.
Li SC, Jia ZK, Yang JJ, Ning XH. Li SC, et al. Front Immunol. 2022 Sep 16;13:975057. doi: 10.3389/fimmu.2022.975057. eCollection 2022. Front Immunol. 2022. PMID: 36189312 Free PMC article.
Kidney cancer is one of the most common urological cancers worldwide, and kidney renal clear cell cancer (KIRC) is the major histologic subtype. Our previous study found that von-Hippel Lindau (VHL) gene mutation, the dominant reason for sporadic KIRC and her …
Kidney cancer is one of the most common urological cancers worldwide, and kidney renal clear cell cancer (KIRC) is the …
Genetics of Primary Aldosteronism.
Scholl UI. Scholl UI. Hypertension. 2022 May;79(5):887-897. doi: 10.1161/HYPERTENSIONAHA.121.16498. Epub 2022 Feb 10. Hypertension. 2022. PMID: 35139664 Free PMC article. Review.
More than 90% of aldosterone-producing adenomas carry somatic mutations in K(+) channel Kir3.4 (KCNJ5), Ca(2+) channel Ca(V)1.3 (CACNA1D), alpha-1 subunit of the Na(+)/K(+) ATPase (ATP1A1), plasma membrane Ca(2+) transporting ATPase 3 (ATP2B3), Ca(2+) channel Ca(V)3.2 (CAC …
More than 90% of aldosterone-producing adenomas carry somatic mutations in K(+) channel Kir3.4 (KCNJ5), Ca(2+) channel Ca(V)1.3 (CACNA1D), a …
Downregulation of ATP1A1 promotes cancer development in renal cell carcinoma.
Zhang D, Zhang P, Yang P, He Y, Wang X, Yang Y, Zhu H, Xu N, Liang S. Zhang D, et al. Clin Proteomics. 2017 May 4;14:15. doi: 10.1186/s12014-017-9150-4. eCollection 2017. Clin Proteomics. 2017. PMID: 28484360 Free PMC article.
BACKGROUND: Aberrant expression of Na(+)/K(+)-ATPase alpha1 subunit (ATP1A1) is widely observed in multiple types of tumors, and its tissue-specific expression relates to cancer development. ...CONCLUSIONS: Our in vitro and in vivo data of ATP1A1 inhibitory r …
BACKGROUND: Aberrant expression of Na(+)/K(+)-ATPase alpha1 subunit (ATP1A1) is widely observed in multiple types of tumors, and its …
Abnormal expression of ATP1A1 and ATP1A2 in breast cancer.
Bogdanov A, Moiseenko F, Dubina M. Bogdanov A, et al. F1000Res. 2017 Jan 5;6:10. doi: 10.12688/f1000research.10481.1. eCollection 2017. F1000Res. 2017. PMID: 28529692 Free PMC article.
Breast cancer is the first in incidence and the second in death among all solid tumors occurring in women. ...We found overexpression of the ATP1A1 and down-regulation of the ATP1A2. We expect that our research could help to improve the understanding of predictive a …
Breast cancer is the first in incidence and the second in death among all solid tumors occurring in women. ...We found overexpression …
Hypomethylation of ATP1A1 Is Associated with Poor Prognosis and Cancer Progression in Triple-Negative Breast Cancer.
Kim Y, Ko JY, Kong HK, Lee M, Chung W, Lim S, Son D, Oh S, Park JW, Kim DY, Lee M, Han W, Park WY, Yoo KH, Park JH. Kim Y, et al. Cancers (Basel). 2024 Apr 25;16(9):1666. doi: 10.3390/cancers16091666. Cancers (Basel). 2024. PMID: 38730618 Free PMC article.
Dysregulated DNA methylation in cancer is critical in the transcription machinery associated with cancer progression. ...The Cancer Genome Atlas (TCGA) database also showed that hypomethylation and high expression of ATP1A1 were strongly associated wit …
Dysregulated DNA methylation in cancer is critical in the transcription machinery associated with cancer progression. ...The …
Primary Aldosteronism.
Funder JW. Funder JW. Hypertension. 2019 Sep;74(3):458-466. doi: 10.1161/HYPERTENSIONAHA.119.12935. Epub 2019 Jul 22. Hypertension. 2019. PMID: 31327272 Free article. Review. No abstract available.
ATP1A1 Mutant in Aldosterone-Producing Adenoma Leads to Cell Proliferation.
Kobuke K, Oki K, Gomez-Sanchez CE, Gomez-Sanchez EP, Itcho K, Ohno H, Nagano G, Yoshii Y, Baba R, Kodama T, Arihiro K, Hattori N, Yoneda M. Kobuke K, et al. Int J Mol Sci. 2021 Oct 12;22(20):10981. doi: 10.3390/ijms222010981. Int J Mol Sci. 2021. PMID: 34681640 Free PMC article.
We performed transcriptome analysis in APAs with ATP1A1 mutation. ATP1A1 L104R mutation were modulated in human adrenocortical carcinoma (HAC15) cells (ATP1A1-mutant cells), and we evaluated cell proliferation and molecular signaling events. ...We demonstrate …
We performed transcriptome analysis in APAs with ATP1A1 mutation. ATP1A1 L104R mutation were modulated in human adrenocortical …
Somatic mutations of the ATP1A1 gene and aldosterone-producing adenomas.
Gomez-Sanchez CE, Kuppusamy M, Gomez-Sanchez EP. Gomez-Sanchez CE, et al. Mol Cell Endocrinol. 2015 Jun 15;408:213-9. doi: 10.1016/j.mce.2014.12.004. Epub 2014 Dec 10. Mol Cell Endocrinol. 2015. PMID: 25496839 Free PMC article. Review.
This review concentrates on the molecular and physiological mechanisms by which mutations of the ATP1A1 gene increase aldosterone production....
This review concentrates on the molecular and physiological mechanisms by which mutations of the ATP1A1 gene increase aldosterone pro …
158 results