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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 2
1996 2
1997 2
1998 7
1999 18
2000 10
2001 8
2002 10
2003 12
2004 21
2005 22
2006 17
2007 12
2008 17
2009 16
2010 24
2011 21
2012 17
2013 18
2014 18
2015 21
2016 19
2017 18
2018 19
2019 26
2020 25
2021 17
2022 25
2023 24
2024 6

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412 results

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Page 1
KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling.
Ando K, Tong L, Peng D, Vázquez-Liébanas E, Chiyoda H, He L, Liu J, Kawakami K, Mochizuki N, Fukuhara S, Grutzendler J, Betsholtz C. Ando K, et al. Dev Cell. 2022 Jun 6;57(11):1383-1399.e7. doi: 10.1016/j.devcel.2022.04.019. Epub 2022 May 18. Dev Cell. 2022. PMID: 35588738 Free article.
Loss- or gain-of-function mutations in ATP-sensitive potassium channel (K-ATP)-encoding genes, KCNJ8 and ABCC9, cause human central nervous system disorders with unknown pathogenesis. ...We show that genetic/chemical inhibition or activation of KCNJ8/ABCC9-containin …
Loss- or gain-of-function mutations in ATP-sensitive potassium channel (K-ATP)-encoding genes, KCNJ8 and ABCC9, cause human central n …
ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target.
Nelson PT, Jicha GA, Wang WX, Ighodaro E, Artiushin S, Nichols CG, Fardo DW. Nelson PT, et al. Ageing Res Rev. 2015 Nov;24(Pt B):111-25. doi: 10.1016/j.arr.2015.07.007. Epub 2015 Jul 28. Ageing Res Rev. 2015. PMID: 26226329 Free PMC article. Review.
The ABCC9 gene and its polypeptide product, SUR2, are increasingly implicated in human neurologic disease, including prevalent diseases of the aged brain. ...For example, Cantu syndrome is a result of ABCC9 mutations; we discuss neurologic manifestations of this gen …
The ABCC9 gene and its polypeptide product, SUR2, are increasingly implicated in human neurologic disease, including prevalent diseas …
Brugada Syndrome.
Brugada R, Campuzano O, Sarquella-Brugada G, Brugada P, Brugada J, Hong K. Brugada R, et al. 2005 Mar 31 [updated 2022 Aug 25]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2005 Mar 31 [updated 2022 Aug 25]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301690 Free Books & Documents. Review.
LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry.
Katsumata Y, Fardo DW, Shade LMP; Alzheimer’s Disease Genetics Consortium; Nelson PT. Katsumata Y, et al. J Neuropathol Exp Neurol. 2023 Aug 21;82(9):760-768. doi: 10.1093/jnen/nlad059. J Neuropathol Exp Neurol. 2023. PMID: 37528055 Free PMC article.
In terms of genetic risk factors, LATE-NC and/or HS are associated with single nucleotide variants (SNVs) in 3 genes-TMEM106B (rs1990622), GRN (rs5848), and ABCC9 (rs1914361 and rs701478). We evaluated these 3 genes in convenience samples of individuals of African ancestry …
In terms of genetic risk factors, LATE-NC and/or HS are associated with single nucleotide variants (SNVs) in 3 genes-TMEM106B (rs1990622), G …
Abcc9 is required for the transition to oxidative metabolism in the newborn heart.
Fahrenbach JP, Stoller D, Kim G, Aggarwal N, Yerokun B, Earley JU, Hadhazy M, Shi NQ, Makielski JC, McNally EM. Fahrenbach JP, et al. FASEB J. 2014 Jul;28(7):2804-15. doi: 10.1096/fj.13-244459. Epub 2014 Mar 19. FASEB J. 2014. PMID: 24648545 Free PMC article.
Abcc9 also encodes a smaller protein enriched in the mitochondria. We now deleted exon 5 of Abcc9 to ablate expression of both plasma membrane and mitochondria-associated Abcc9-encoded proteins, and found that the myocardium failed to acquire normal mature me …
Abcc9 also encodes a smaller protein enriched in the mitochondria. We now deleted exon 5 of Abcc9 to ablate expression of both …
ABCC8 and ABCC9: ABC transporters that regulate K+ channels.
Bryan J, Muñoz A, Zhang X, Düfer M, Drews G, Krippeit-Drews P, Aguilar-Bryan L. Bryan J, et al. Pflugers Arch. 2007 Feb;453(5):703-18. doi: 10.1007/s00424-006-0116-z. Epub 2006 Aug 8. Pflugers Arch. 2007. PMID: 16897043 Review.
The sulfonylurea receptors (SURs) ABCC8/SUR1 and ABCC9/SUR2 are members of the C-branch of the transport adenosine triphosphatase superfamily. ...
The sulfonylurea receptors (SURs) ABCC8/SUR1 and ABCC9/SUR2 are members of the C-branch of the transport adenosine triphosphatase sup …
Novel loss-of-function variants expand ABCC9-related intellectual disability and myopathy syndrome.
Efthymiou S, Scala M, Nagaraj V, Ochenkowska K, Komdeur FL, Liang RA, Abdel-Hamid MS, Sultan T, Barøy T, Van Ghelue M, Vona B, Maroofian R, Zafar F, Alkuraya FS, Zaki MS, Severino M, Duru KC, Tryon RC, Brauteset LV, Ansari M, Hamilton M, van Haelst MM, van Haaften G, Zara F, Houlden H, Samarut É, Nichols CG, Smeland MF, McClenaghan C. Efthymiou S, et al. Brain. 2024 Jan 13:awae010. doi: 10.1093/brain/awae010. Online ahead of print. Brain. 2024. PMID: 38217872
Loss-of-function mutation of ABCC9, the gene encoding the SUR2 subunit of ATP sensitive-potassium (KATP) channels, was recently associated with autosomal recessive ABCC9-related intellectual disability and myopathy syndrome (AIMS). Here we identify nine additional s …
Loss-of-function mutation of ABCC9, the gene encoding the SUR2 subunit of ATP sensitive-potassium (KATP) channels, was recently assoc …
ABCC9 Is Downregulated and Prone to Microsatellite Instability on ABCC9tetra in Canine Breast Cancer.
Hao P, Song KY, Wang SQ, Huang XJ, Yao DW, Yang DJ. Hao P, et al. Front Vet Sci. 2022 Jan 7;8:819293. doi: 10.3389/fvets.2021.819293. eCollection 2021. Front Vet Sci. 2022. PMID: 35071399 Free PMC article.
Furthermore, the promoter methylation results of the adenosine triphosphate binding cassette subfamily C member 9 (ABCC9) showed that there was a high level of methylation in breast tissues, but only one case showed a significant elevation compared with the control. ...Gen …
Furthermore, the promoter methylation results of the adenosine triphosphate binding cassette subfamily C member 9 (ABCC9) showed that …
Case Report: Loss-of-Function ABCC9 Genetic Variant Associated With Ventricular Fibrillation.
Zaytseva A, Tulintseva T, Fomicheva Y, Mikhailova V, Treshkur T, Kostareva A. Zaytseva A, et al. Front Genet. 2022 Apr 13;13:718853. doi: 10.3389/fgene.2022.718853. eCollection 2022. Front Genet. 2022. PMID: 35495129 Free PMC article.
Genetic variants in the ABCC9 gene, encoding the SUR2 auxiliary subunit from K(ATP) channels, were previously linked with various inherited diseases. ...This case sheds light on the consequences of K(ATP) channel dysfunction in the cardiovascular system and underlines the …
Genetic variants in the ABCC9 gene, encoding the SUR2 auxiliary subunit from K(ATP) channels, were previously linked with various inh …
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.
Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, Hokkanen SRK, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovacs GG, Kukull WA, Levey AI, Makkinejad N, Montine TJ, Murayama S, Murray ME, Nag S, Rissman RA, Seeley WW, Sperling RA, White CL 3rd, Yu L, Schneider JA. Nelson PT, et al. Brain. 2019 Jun 1;142(6):1503-1527. doi: 10.1093/brain/awz099. Brain. 2019. PMID: 31039256 Free PMC article.
Genetic studies have thus far indicated five genes with risk alleles for LATE-NC: GRN, TMEM106B, ABCC9, KCNMB2, and APOE. The discovery of these genetic risk variants indicate that LATE shares pathogenetic mechanisms with both frontotemporal lobar degeneration and Alzheime …
Genetic studies have thus far indicated five genes with risk alleles for LATE-NC: GRN, TMEM106B, ABCC9, KCNMB2, and APOE. The discove …
412 results