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Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors.
George J, Chen Y, Abdelfattah N, Yamamoto K, Gallup TD, Adamson SI, Rybinski B, Srivastava A, Kumar P, Lee MG, Baskin DS, Jiang W, Choi JM, Flavahan W, Chuang JH, Kim BY, Xu J, Jung SY, Yun K. George J, et al. Among authors: abdelfattah n. Cancer Res Commun. 2022 Jun;2(6):402-416. doi: 10.1158/2767-9764.crc-22-0124. Epub 2022 Jun 6. Cancer Res Commun. 2022. PMID: 36688010 Free PMC article.
Targeting aberrant replication and DNA repair events for treating breast cancers.
Rajamanickam S, Park JH, Subbarayalu P, Timilsina S, Bates K, Yadav P, Nirzhor SSR, Eedunuri V, Mohammad TA, Jung KH, Onyeagucha B, Abdelfattah N, Benevides R, Lee G, Chen Y, Vadlamudi R, Brenner A, Kaklamani V, Jatoi I, Kuhn J, Hromas R, Gupta YK, Kaipparettu BA, Arbiser JL, Rao MK. Rajamanickam S, et al. Among authors: abdelfattah n. Commun Biol. 2022 May 24;5(1):493. doi: 10.1038/s42003-022-03413-w. Commun Biol. 2022. PMID: 35610507 Free PMC article.
Novel post-transcriptional and post-translational regulation of pro-apoptotic protein BOK and anti-apoptotic protein Mcl-1 determine the fate of breast cancer cells to survive or die.
Onyeagucha B, Subbarayalu P, Abdelfattah N, Rajamanickam S, Timilsina S, Guzman R, Zeballos C, Eedunuri V, Bansal S, Mohammad T, Chen Y, Vadlamudi RK, Rao MK. Onyeagucha B, et al. Among authors: abdelfattah n. Oncotarget. 2017 Sep 12;8(49):85984-85996. doi: 10.18632/oncotarget.20841. eCollection 2017 Oct 17. Oncotarget. 2017. PMID: 29156771 Free PMC article.
Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression.
Panneerdoss S, Eedunuri VK, Yadav P, Timilsina S, Rajamanickam S, Viswanadhapalli S, Abdelfattah N, Onyeagucha BC, Cui X, Lai Z, Mohammad TA, Gupta YK, Huang TH, Huang Y, Chen Y, Rao MK. Panneerdoss S, et al. Among authors: abdelfattah n. Sci Adv. 2018 Oct 3;4(10):eaar8263. doi: 10.1126/sciadv.aar8263. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30306128 Free PMC article.
M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression.
Yadav P, Subbarayalu P, Medina D, Nirzhor S, Timilsina S, Rajamanickam S, Eedunuri VK, Gupta Y, Zheng S, Abdelfattah N, Huang Y, Vadlamudi R, Hromas R, Meltzer P, Houghton P, Chen Y, Rao MK. Yadav P, et al. Among authors: abdelfattah n. Cancer Res. 2022 May 16;82(10):1872-1889. doi: 10.1158/0008-5472.CAN-21-2106. Cancer Res. 2022. PMID: 35303054 Free PMC article.
The antidepressant imipramine inhibits breast cancer growth by targeting estrogen receptor signaling and DNA repair events.
Timilsina S, Rajamanickam S, Rao A, Subbarayalu P, Nirzhor S, Abdelfattah N, Viswanadhapalli S, Chen Y, Jatoi I, Brenner A, Rao MK, Vadlamudi R, Kaklamani V. Timilsina S, et al. Among authors: abdelfattah n. Cancer Lett. 2022 Aug 1;540:215717. doi: 10.1016/j.canlet.2022.215717. Epub 2022 May 12. Cancer Lett. 2022. PMID: 35568265 Free PMC article.
65 results