Abel ED - Search Results

1

Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy.

Ikeda H, Shiojima I, Ozasa Y, Yoshida M, Holzenberger M, Kahn CR, Walsh K, Igarashi T, Abel ED, Komuro I. Ikeda H, et al. Among authors: abel ed. J Mol Cell Cardiol. 2009 Nov;47(5):664-75. doi: 10.1016/j.yjmcc.2009.08.028. Epub 2009 Sep 8. J Mol Cell Cardiol. 2009. PMID: 19744489 Free PMC article.

2

Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression.

Belke DD, Betuing S, Tuttle MJ, Graveleau C, Young ME, Pham M, Zhang D, Cooksey RC, McClain DA, Litwin SE, Taegtmeyer H, Severson D, Kahn CR, Abel ED. Belke DD, et al. Among authors: abel ed. J Clin Invest. 2002 Mar;109(5):629-39. doi: 10.1172/JCI13946. J Clin Invest. 2002. PMID: 11877471 Free PMC article.

3

Akt signaling mediates postnatal heart growth in response to insulin and nutritional status.

Shiojima I, Yefremashvili M, Luo Z, Kureishi Y, Takahashi A, Tao J, Rosenzweig A, Kahn CR, Abel ED, Walsh K. Shiojima I, et al. Among authors: abel ed. J Biol Chem. 2002 Oct 4;277(40):37670-7. doi: 10.1074/jbc.M204572200. Epub 2002 Aug 5. J Biol Chem. 2002. PMID: 12163490 Free article.

4

Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary density.

McQueen AP, Zhang D, Hu P, Swenson L, Yang Y, Zaha VG, Hoffman JL, Yun UJ, Chakrabarti G, Wang Z, Albertine KH, Abel ED, Litwin SE. McQueen AP, et al. Among authors: abel ed. J Mol Cell Cardiol. 2005 Dec;39(6):882-92. doi: 10.1016/j.yjmcc.2005.07.017. Epub 2005 Oct 10. J Mol Cell Cardiol. 2005. PMID: 16216265

5

Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy.

Kim J, Wende AR, Sena S, Theobald HA, Soto J, Sloan C, Wayment BE, Litwin SE, Holzenberger M, LeRoith D, Abel ED. Kim J, et al. Among authors: abel ed. Mol Endocrinol. 2008 Nov;22(11):2531-43. doi: 10.1210/me.2008-0265. Epub 2008 Sep 18. Mol Endocrinol. 2008. PMID: 18801929 Free PMC article.

6

Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction.

Sena S, Hu P, Zhang D, Wang X, Wayment B, Olsen C, Avelar E, Abel ED, Litwin SE. Sena S, et al. Among authors: abel ed. J Mol Cell Cardiol. 2009 Jun;46(6):910-8. doi: 10.1016/j.yjmcc.2009.02.014. Epub 2009 Feb 26. J Mol Cell Cardiol. 2009. PMID: 19249310 Free PMC article.

7

Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents.

Shimizu I, Minamino T, Toko H, Okada S, Ikeda H, Yasuda N, Tateno K, Moriya J, Yokoyama M, Nojima A, Koh GY, Akazawa H, Shiojima I, Kahn CR, Abel ED, Komuro I. Shimizu I, et al. Among authors: abel ed. J Clin Invest. 2010 May;120(5):1506-14. doi: 10.1172/JCI40096. Epub 2010 Apr 19. J Clin Invest. 2010. PMID: 20407209 Free PMC article.

8

Genetic loss of insulin receptors worsens cardiac efficiency in diabetes.

Bugger H, Riehle C, Jaishy B, Wende AR, Tuinei J, Chen D, Soto J, Pires KM, Boudina S, Theobald HA, Luptak I, Wayment B, Wang X, Litwin SE, Weimer BC, Abel ED. Bugger H, et al. Among authors: abel ed. J Mol Cell Cardiol. 2012 May;52(5):1019-26. doi: 10.1016/j.yjmcc.2012.02.001. Epub 2012 Feb 9. J Mol Cell Cardiol. 2012. PMID: 22342406 Free PMC article.

9

Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation.

Zhu Y, Pereira RO, O'Neill BT, Riehle C, Ilkun O, Wende AR, Rawlings TA, Zhang YC, Zhang Q, Klip A, Shiojima I, Walsh K, Abel ED. Zhu Y, et al. Among authors: abel ed. Mol Endocrinol. 2013 Jan;27(1):172-84. doi: 10.1210/me.2012-1210. Epub 2012 Nov 30. Mol Endocrinol. 2013. PMID: 23204326 Free PMC article.

10

Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.

Wende AR, O'Neill BT, Bugger H, Riehle C, Tuinei J, Buchanan J, Tsushima K, Wang L, Caro P, Guo A, Sloan C, Kim BJ, Wang X, Pereira RO, McCrory MA, Nye BG, Benavides GA, Darley-Usmar VM, Shioi T, Weimer BC, Abel ED. Wende AR, et al. Among authors: abel ed. Mol Cell Biol. 2015 Mar;35(5):831-46. doi: 10.1128/MCB.01109-14. Epub 2014 Dec 22. Mol Cell Biol. 2015. PMID: 25535334 Free PMC article.

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