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A novel antibiotic class targeting the lipopolysaccharide transporter.
Zampaloni C, Mattei P, Bleicher K, Winther L, Thäte C, Bucher C, Adam JM, Alanine A, Amrein KE, Baidin V, Bieniossek C, Bissantz C, Boess F, Cantrill C, Clairfeuille T, Dey F, Di Giorgio P, du Castel P, Dylus D, Dzygiel P, Felici A, García-Alcalde F, Haldimann A, Leipner M, Leyn S, Louvel S, Misson P, Osterman A, Pahil K, Rigo S, Schäublin A, Scharf S, Schmitz P, Stoll T, Trauner A, Zoffmann S, Kahne D, Young JAT, Lobritz MA, Bradley KA. Zampaloni C, et al. Among authors: adam jm. Nature. 2024 Jan;625(7995):566-571. doi: 10.1038/s41586-023-06873-0. Epub 2024 Jan 3. Nature. 2024. PMID: 38172634 Free PMC article.
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
Omar F, Findlay JE, Carfray G, Allcock RW, Jiang Z, Moore C, Muir AL, Lannoy M, Fertig BA, Mai D, Day JP, Bolger G, Baillie GS, Schwiebert E, Klussmann E, Pyne NJ, Ong ACM, Bowers K, Adam JM, Adams DR, Houslay MD, Henderson DJP. Omar F, et al. Among authors: adam jm. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13320-13329. doi: 10.1073/pnas.1822113116. Epub 2019 Jun 17. Proc Natl Acad Sci U S A. 2019. PMID: 31209056 Free PMC article.
Therapy with a Selective Cannabinoid Receptor Type 2 Agonist Limits Albuminuria and Renal Injury in Mice with Type 2 Diabetic Nephropathy.
Zoja C, Locatelli M, Corna D, Villa S, Rottoli D, Nava V, Verde R, Piscitelli F, Di Marzo V, Fingerle J, Adam JM, Rothenhaeusler B, Ottaviani G, Bénardeau A, Abbate M, Remuzzi G, Benigni A. Zoja C, et al. Among authors: adam jm. Nephron. 2016;132(1):59-69. doi: 10.1159/000442679. Epub 2015 Dec 9. Nephron. 2016. PMID: 26646377
66 results