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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1965 3
1969 1
1975 1
1977 1
1980 2
1984 1
1986 1
1988 5
1990 1
1991 1
1992 2
1993 4
1994 1
1995 3
1996 4
1997 3
1998 2
1999 1
2000 1
2001 1
2002 1
2003 2
2004 3
2005 3
2006 4
2007 11
2008 6
2009 4
2010 12
2011 5
2012 7
2013 10
2014 15
2015 9
2016 18
2017 15
2018 21
2019 26
2020 30
2021 39
2022 44
2023 40
2024 19

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356 results

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AEN Suppresses the Replication of Porcine Epidemic Diarrhea Virus by Inducing the Expression of Type I IFN and ISGs in MARC-145 Cells.
Luo M, Ma J, Pan X, Zhang X, Yao H. Luo M, et al. Pathogens. 2023 Dec 27;13(1):24. doi: 10.3390/pathogens13010024. Pathogens. 2023. PMID: 38251332 Free PMC article.
In contrast, the amount of AEN protein decreased as viral replication increased. It was found that PEDV nsp1 and nsp5 mediated the decrease in AEN production, suggesting that an increase in AEN was not conducive to virus replication. By comparing AEN a …
In contrast, the amount of AEN protein decreased as viral replication increased. It was found that PEDV nsp1 and nsp5 mediated the de …
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, … See abstract for full author list ➔ Klionsky DJ, et al. Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. Autophagy. 2016. PMID: 26799652 Free PMC article. No abstract available.
Esophageal Necrosis.
Richards J, Wei R, Anjum F. Richards J, et al. 2023 May 22. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 May 22. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 34283441 Free Books & Documents.
Acute esophageal necrosis (AEN), also known as the black esophagus, Gurvit syndrome, or acute necrotizing esophagitis, is a rare and life-threatening condition. ...Overall mortality associated with AEN is approximately 30%; however, mortality specific to AEN
Acute esophageal necrosis (AEN), also known as the black esophagus, Gurvit syndrome, or acute necrotizing esophagitis, is a rare and …
p53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosis.
Kawase T, Ichikawa H, Ohta T, Nozaki N, Tashiro F, Ohki R, Taya Y. Kawase T, et al. Oncogene. 2008 Jun 19;27(27):3797-810. doi: 10.1038/onc.2008.32. Epub 2008 Feb 11. Oncogene. 2008. PMID: 18264133
AEN induces apoptosis by itself, and the conserved domains are essential for both AEN nuclease activity and its apoptosis-inducing ability. ...We also show the dislocation of nucleophosmin in conjunction with the translocation of AEN to the nucleoplasm, indic
AEN induces apoptosis by itself, and the conserved domains are essential for both AEN nuclease activity and its apoptosis-indu
CT or Invasive Coronary Angiography in Stable Chest Pain.
DISCHARGE Trial Group; Maurovich-Horvat P, Bosserdt M, Kofoed KF, Rieckmann N, Benedek T, Donnelly P, Rodriguez-Palomares J, Erglis A, Štěchovský C, Šakalyte G, Čemerlić Adić N, Gutberlet M, Dodd JD, Diez I, Davis G, Zimmermann E, Kępka C, Vidakovic R, Francone M, Ilnicka-Suckiel M, Plank F, Knuuti J, Faria R, Schröder S, Berry C, Saba L, Ruzsics B, Kubiak C, Gutierrez-Ibarluzea I, Schultz Hansen K, Müller-Nordhorn J, Merkely B, Knudsen AD, Benedek I, Orr C, Xavier Valente F, Zvaigzne L, Suchánek V, Zajančkauskiene L, Adić F, Woinke M, Hensey M, Lecumberri I, Thwaite E, Laule M, Kruk M, Neskovic AN, Mancone M, Kuśmierz D, Feuchtner G, Pietilä M, Gama Ribeiro V, Drosch T, Delles C, Matta G, Fisher M, Szilveszter B, Larsen L, Ratiu M, Kelly S, Garcia Del Blanco B, Rubio A, Drobni ZD, Jurlander B, Rodean I, Regan S, Cuéllar Calabria H, Boussoussou M, Engstrøm T, Hodas R, Napp AE, Haase R, Feger S, Serna-Higuita LM, Neumann K, Dreger H, Rief M, Wieske V, Estrella M, Martus P, Dewey M. DISCHARGE Trial Group, et al. N Engl J Med. 2022 Apr 28;386(17):1591-1602. doi: 10.1056/NEJMoa2200963. Epub 2022 Mar 4. N Engl J Med. 2022. PMID: 35240010 Clinical Trial.
Identification of a novel ionizing radiation-induced nuclease, AEN, and its functional characterization in apoptosis.
Lee JH, Koh YA, Cho CK, Lee SJ, Lee YS, Bae S. Lee JH, et al. Biochem Biophys Res Commun. 2005 Nov 11;337(1):39-47. doi: 10.1016/j.bbrc.2005.08.264. Biochem Biophys Res Commun. 2005. PMID: 16171785
The AEN protein revealed DNase activity by cleaving various DNA substrates. ...Irradiation of AEN-expressing cells resulted in synergistic increase of apoptosis whereas AEN deletion mutant in exonuclease domain did not. ...
The AEN protein revealed DNase activity by cleaving various DNA substrates. ...Irradiation of AEN-expressing cells resulted in …
Brazilian Journal of Psychiatry.
Quevedo J, Nardi AE, da Silva AG. Quevedo J, et al. Braz J Psychiatry. 2019 Jan-Mar;41(1):1-2. doi: 10.1590/1516-4446-2018-4103. Braz J Psychiatry. 2019. PMID: 33683282 Free PMC article. No abstract available.
Multiple Bonding in AeN- (Ae = Ca, Sr, Ba).
Cui LJ, Liu YQ, Wang MH, Yan B, Pan S, Cui ZH, Frenking G. Cui LJ, et al. Chemistry. 2024 Apr 15:e202400714. doi: 10.1002/chem.202400714. Online ahead of print. Chemistry. 2024. PMID: 38622057
Quantum chemical calculations using ab initio methods at the MRCI+Q(8,9)/def2-QZVPPD and CCSD(T)/def2-QZVPPD levels as well as density functional theory are reported for the diatomic molecules AeN- (Ae = Ca, Sr, Ba). The nature of the bonds is analyzed with a variety of me …
Quantum chemical calculations using ab initio methods at the MRCI+Q(8,9)/def2-QZVPPD and CCSD(T)/def2-QZVPPD levels as well as density funct …
The Black Esophagus.
Thomas M, Sostre Santiago V, Suhail FK, Polanco Serra G, Manocha D. Thomas M, et al. Cureus. 2021 Oct 11;13(10):e18655. doi: 10.7759/cureus.18655. eCollection 2021 Oct. Cureus. 2021. PMID: 34790441 Free PMC article.
Acute esophageal necrosis (AEN), commonly referred to as black esophagus, is a rare clinical condition resulting from a combination of ischemic insult and thromboembolic injury to the esophagus. It is characterized by the circumferential black appearance of the esophagus. …
Acute esophageal necrosis (AEN), commonly referred to as black esophagus, is a rare clinical condition resulting from a combination o …
356 results