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Long-term exposure to GDNF induces dephosphorylation of Ret, AKT, and ERK1/2, and is ineffective at protecting midbrain dopaminergic neurons in cellular models of Parkinson's disease.
Mesa-Infante V, Afonso-Oramas D, Salas-Hernández J, Rodríguez-Núñez J, Barroso-Chinea P. Mesa-Infante V, et al. Among authors: afonso oramas d. Mol Cell Neurosci. 2022 Jan;118:103684. doi: 10.1016/j.mcn.2021.103684. Epub 2021 Nov 23. Mol Cell Neurosci. 2022. PMID: 34826608 Free article.
Tetrahydrobiopterin stimulates L-DOPA release from striatal tissue.
Abreu-González P, González-Hernández T, Afonso-Oramas D, Cruz-Muros I, Barroso-Chinea P, González MC. Abreu-González P, et al. Eur J Pharmacol. 2006 Jul 10;541(1-2):33-7. doi: 10.1016/j.ejphar.2006.04.019. Epub 2006 Apr 27. Eur J Pharmacol. 2006. PMID: 16750826
The dopamine transporter is differentially regulated after dopaminergic lesion.
Afonso-Oramas D, Cruz-Muros I, Barroso-Chinea P, Álvarez de la Rosa D, Castro-Hernández J, Salas-Hernández J, Giráldez T, González-Hernández T. Afonso-Oramas D, et al. Neurobiol Dis. 2010 Dec;40(3):518-30. doi: 10.1016/j.nbd.2010.07.012. Epub 2010 Aug 2. Neurobiol Dis. 2010. PMID: 20688165
Vulnerability of mesostriatal dopaminergic neurons in Parkinson's disease.
González-Hernández T, Cruz-Muros I, Afonso-Oramas D, Salas-Hernandez J, Castro-Hernandez J. González-Hernández T, et al. Front Neuroanat. 2010 Oct 20;4:140. doi: 10.3389/fnana.2010.00140. eCollection 2010. Front Neuroanat. 2010. PMID: 21079748 Free PMC article.
Prolonged treatment with pramipexole promotes physical interaction of striatal dopamine D3 autoreceptors with dopamine transporters to reduce dopamine uptake.
Castro-Hernández J, Afonso-Oramas D, Cruz-Muros I, Salas-Hernández J, Barroso-Chinea P, Moratalla R, Millan MJ, González-Hernández T. Castro-Hernández J, et al. Among authors: afonso oramas d. Neurobiol Dis. 2015 Feb;74:325-35. doi: 10.1016/j.nbd.2014.12.007. Epub 2014 Dec 12. Neurobiol Dis. 2015. PMID: 25511804
22 results