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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1946 5
1947 1
1948 3
1949 1
1951 2
1952 2
1953 1
1954 3
1955 4
1956 7
1957 2
1958 1
1959 2
1960 10
1961 5
1962 2
1963 3
1964 4
1965 3
1966 3
1967 4
1968 6
1969 8
1970 8
1971 4
1972 4
1973 9
1974 8
1975 29
1976 21
1977 23
1978 33
1979 17
1980 22
1981 26
1982 32
1983 23
1984 32
1985 37
1986 35
1987 32
1988 38
1989 63
1990 62
1991 52
1992 60
1993 64
1994 63
1995 104
1996 119
1997 130
1998 154
1999 153
2000 191
2001 193
2002 214
2003 238
2004 273
2005 338
2006 338
2007 384
2008 463
2009 519
2010 576
2011 664
2012 748
2013 790
2014 786
2015 826
2016 832
2017 827
2018 823
2019 936
2020 989
2021 1092
2022 1006
2023 1084
2024 499

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15,166 results

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Page 1
Pharmacogenetics of warfarin dosing in patients of African and European ancestry.
Shendre A, Dillon C, Limdi NA. Shendre A, et al. Pharmacogenomics. 2018 Nov;19(17):1357-1371. doi: 10.2217/pgs-2018-0146. Epub 2018 Oct 22. Pharmacogenomics. 2018. PMID: 30345882 Free PMC article. Review.
Observational studies have demonstrated the significant impact of single nucleotide polymorphisms in CYP2C9 and VKORC1 on warfarin dose in patients of European ancestry and African-Americans. This evidence supported the design and conduct of clinical trials to asses …
Observational studies have demonstrated the significant impact of single nucleotide polymorphisms in CYP2C9 and VKORC1 on warfarin dose in p …
An atlas of genetic scores to predict multi-omic traits.
Xu Y, Ritchie SC, Liang Y, Timmers PRHJ, Pietzner M, Lannelongue L, Lambert SA, Tahir UA, May-Wilson S, Foguet C, Johansson Å, Surendran P, Nath AP, Persyn E, Peters JE, Oliver-Williams C, Deng S, Prins B, Luan J, Bomba L, Soranzo N, Di Angelantonio E, Pirastu N, Tai ES, van Dam RM, Parkinson H, Davenport EE, Paul DS, Yau C, Gerszten RE, Mälarstig A, Danesh J, Sim X, Langenberg C, Wilson JF, Butterworth AS, Inouye M. Xu Y, et al. Nature. 2023 Apr;616(7955):123-131. doi: 10.1038/s41586-023-05844-9. Epub 2023 Mar 29. Nature. 2023. PMID: 36991119 Free PMC article.
We evaluate the performance of genetic scores through external validation across cohorts of individuals of European, Asian and African American ancestries. In addition, we show the utility of these multi-omic genetic scores by quantifying the genetic control of biol …
We evaluate the performance of genetic scores through external validation across cohorts of individuals of European, Asian and Afr …
Estimates of European American Ancestry in African Americans Using HFE p.C282Y.
Acton RT, Wiener HW, Barton JC. Acton RT, et al. Genet Test Mol Biomarkers. 2020 Sep;24(9):578-583. doi: 10.1089/gtmb.2020.0154. Epub 2020 Aug 4. Genet Test Mol Biomarkers. 2020. PMID: 32757954
Background: HFE p.C282Y (chromosome 6p22.2; exon 4, c.845G>A; rs1800562), a hemochromatosis-associated polymorphism in European Americans, is absent in sub-Saharan West African blacks. Methods: We estimated European American ancestry in African Amer …
Background: HFE p.C282Y (chromosome 6p22.2; exon 4, c.845G>A; rs1800562), a hemochromatosis-associated polymorphism in European Am …
Vascular considerations in glaucoma patients of African and European descent.
Huck A, Harris A, Siesky B, Kim N, Muchnik M, Kanakamedala P, Amireskandari A, Abrams-Tobe L. Huck A, et al. Acta Ophthalmol. 2014 Aug;92(5):e336-40. doi: 10.1111/aos.12354. Epub 2014 Jan 25. Acta Ophthalmol. 2014. PMID: 24460758 Free PMC article. Review.
Glaucoma is the leading cause of blindness in individuals of African descent (AD). While open-angle glaucoma (OAG) disproportionately affects individuals of AD compared with persons of European descent (ED), the physiological mechanisms behind this disparity are lar …
Glaucoma is the leading cause of blindness in individuals of African descent (AD). While open-angle glaucoma (OAG) disproportionately …
Beauty.
Tate SA. Tate SA. Can Rev Sociol. 2022 Nov;59(4):547-549. doi: 10.1111/cars.12406. Epub 2022 Oct 26. Can Rev Sociol. 2022. PMID: 36286338
It is a racialized category/ perception which emerged through centuries of European colonization, Indigenous genocide, African/Black enslavement and indenture resulting in an aesthetic hierarchy with Blackness at the bottom. The coloniality of aesthetics mean …
It is a racialized category/ perception which emerged through centuries of European colonization, Indigenous genocide, African …
Historical genomes elucidate European settlement and the African diaspora in Delaware.
Fleskes RE, Owsley DW, Bruwelheide KS, Barca KG, Griffith DR, Cabana GS, Schurr TG. Fleskes RE, et al. Curr Biol. 2023 Jun 5;33(11):2350-2358.e7. doi: 10.1016/j.cub.2023.04.069. Epub 2023 May 18. Curr Biol. 2023. PMID: 37207647
Previous osteological and mitochondrial DNA (mtDNA) sequence analyses showed a southern group of eight individuals of European maternal descent, buried 15-20 feet from a northern group of three individuals of African maternal descent.(5) Autosomal results further il …
Previous osteological and mitochondrial DNA (mtDNA) sequence analyses showed a southern group of eight individuals of European matern …
Inferring recombination patterns in African populations.
van Eeden G, Uren C, Möller M, Henn BM. van Eeden G, et al. Hum Mol Genet. 2021 Apr 26;30(R1):R11-R16. doi: 10.1093/hmg/ddab020. Hum Mol Genet. 2021. PMID: 33445180 Free PMC article. Review.
Although several high-resolution recombination maps exist for European-descent populations, the recombination landscape of African populations remains relatively understudied. ...In this review, we discuss various recombination inference methods, and the strengths a …
Although several high-resolution recombination maps exist for European-descent populations, the recombination landscape of African …
Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study.
Rizig M, Bandres-Ciga S, Makarious MB, Ojo OO, Crea PW, Abiodun OV, Levine KS, Abubakar SA, Achoru CO, Vitale D, Adeniji OA, Agabi OP, Koretsky MJ, Agulanna U, Hall DA, Akinyemi RO, Xie T, Ali MW, Shamim EA, Ani-Osheku I, Padmanaban M, Arigbodi OM, Standaert DG, Bello AH, Dean MN, Erameh CO, Elsayed I, Farombi TH, Okunoye O, Fawale MB, Billingsley KJ, Imarhiagbe FA, Jerez PA, Iwuozo EU, Baker B, Komolafe MA, Malik L, Nwani PO, Daida K, Nwazor EO, Miano-Burkhardt A, Nyandaiti YW, Fang ZH, Obiabo YO, Kluss JH, Odeniyi OA, Hernandez DG, Odiase FE, Tayebi N, Ojini FI, Sidranksy E, Onwuegbuzie GA, D'Souza AM, Osaigbovo GO, Berhe B, Osemwegie N, Reed X, Oshinaike OO, Leonard HL, Otubogun FM, Alvarado CX, Oyakhire SI, Ozomma SI, Samuel SC, Taiwo FT, Wahab KW, Zubair YA, Iwaki H, Kim JJ, Morris HR, Hardy J, Nalls MA, Heilbron K, Norcliffe-Kaufmann L; Nigeria Parkinson Disease Research Network; International Parkinson's Disease Genomics Consortium Africa; Black and African American Connections to Parkinson's Disease Study Group; 23andMe Research Team; Blauwendraat C, Houlden H, Singleton A, Okubadejo NU; Global Parkinson's Genetics Program. Rizig M, et al. Lancet Neurol. 2023 Nov;22(11):1015-1025. doi: 10.1016/S1474-4422(23)00283-1. Epub 2023 Aug 23. Lancet Neurol. 2023. PMID: 37633302
METHODS: We performed a genome-wide association study (GWAS) in people of African and African admixed ancestry with and without Parkinson's disease. ...INTERPRETATION: Our study identified a novel genetic risk factor in GBA1 in people of African …
METHODS: We performed a genome-wide association study (GWAS) in people of African and African admixed ancestry with and …
Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition.
Hu W, Hao Z, Du P, Di Vincenzo F, Manzi G, Cui J, Fu YX, Pan YH, Li H. Hu W, et al. Science. 2023 Sep;381(6661):979-984. doi: 10.1126/science.abq7487. Epub 2023 Aug 31. Science. 2023. PMID: 37651513
This bottleneck is congruent with a substantial chronological gap in the available African and Eurasian fossil record. Our results provide new insights into our ancestry and suggest a coincident speciation event....
This bottleneck is congruent with a substantial chronological gap in the available African and Eurasian fossil record. Our results pr …
Genetic admixture in Brazil.
Pena SDJ, Santos FR, Tarazona-Santos E. Pena SDJ, et al. Am J Med Genet C Semin Med Genet. 2020 Dec;184(4):928-938. doi: 10.1002/ajmg.c.31853. Epub 2020 Nov 18. Am J Med Genet C Semin Med Genet. 2020. PMID: 33205899 Review.
We review studies from our laboratories using different molecular tools to characterize the Amerindian, European and African ancestry of Brazilians. Initially we used uniparental DNA markers to investigate the contribution of distinct Y chromosome and mitochondrial …
We review studies from our laboratories using different molecular tools to characterize the Amerindian, European and African a …
15,166 results
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