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Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor.
Watanabe A, Hataida H, Inoue N, Kamon K, Baba K, Sasaki K, Kimura R, Sasaki H, Eura Y, Ni WF, Shibasaki Y, Waguri S, Kokame K, Shiba Y. Watanabe A, et al. Biol Open. 2021 Sep 15;10(9):bio058789. doi: 10.1242/bio.058789. Epub 2021 Sep 1. Biol Open. 2021. PMID: 34369554 Free PMC article.
In this study, we performed siRNA screening of ArfGAPs to investigate the role of ArfGAPs in the biogenesis of WPBs. We found two ArfGAPs, SMAP1 and AGFG2, to be involved in WPB size and vWF exocytosis, respectively. SMAP1 depletion resulted in small-sized WPBs, and the ly …
In this study, we performed siRNA screening of ArfGAPs to investigate the role of ArfGAPs in the biogenesis of WPBs. We found two ArfGAPs, S …
TSPOAP1-AS1: A Novel Biomarker for the Prognosis and Therapeutic Target in Cervical Cancer.
Li J, Ye Z, Gan Y, Li D, Chen Y. Li J, et al. Comb Chem High Throughput Screen. 2025 Jan 13. doi: 10.2174/0113862073355878241117153320. Online ahead of print. Comb Chem High Throughput Screen. 2025. PMID: 39812059
A ceRNA network of TSPOAP1-AS1/miR-17-5p/AGFG2 was constructed in CESC. In CESC, a ceRNA network involving TSPOAP1-AS1/miR-17-5p/AGFG2 was successfully established. When comparing CESC cell lines with HcerEpic, the expression of TSPOAP1-AS1 and AGFG2 decrease …
A ceRNA network of TSPOAP1-AS1/miR-17-5p/AGFG2 was constructed in CESC. In CESC, a ceRNA network involving TSPOAP1-AS1/miR-17-5p/A …
Organization patterns of the AGFG genes: an evolutionary study.
Panaro MA, Acquafredda A, Calvello R, Lisi S, Dragone T, Cianciulli A. Panaro MA, et al. Immunopharmacol Immunotoxicol. 2011 Mar;33(1):111-23. doi: 10.3109/08923973.2010.485617. Immunopharmacol Immunotoxicol. 2011. PMID: 21284487
In some Drosophilae the core module is preceded by a long stretch of more than 300 coding nucleotides, but this additional module is absent in other Drosophilae and in all AGFG1s of other species. The AGFG2 molecules emerged later in evolution, possibly deriving from a dup …
In some Drosophilae the core module is preceded by a long stretch of more than 300 coding nucleotides, but this additional module is absent …
THD-Tricluster: A robust triclustering technique and its application in condition specific change analysis in HIV-1 progression data.
Kakati T, Ahmed HA, Bhattacharyya DK, Kalita JK. Kakati T, et al. Comput Biol Chem. 2018 Aug;75:154-167. doi: 10.1016/j.compbiolchem.2018.05.007. Epub 2018 May 7. Comput Biol Chem. 2018. PMID: 29787933
THD-Tricluster could identify 38 most responsible genes for the deadly disease which includes GATA3, EGR1, JUN, ELF1, AGFG1, AGFG2, CX3CR1, CXCL12, CCR5, CCR2, and many others. The results are validated using GeneCard and other established results....
THD-Tricluster could identify 38 most responsible genes for the deadly disease which includes GATA3, EGR1, JUN, ELF1, AGFG1, AGFG2, C …