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Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease.
van der Graaf A, Zorro MM, Claringbould A, Võsa U, Aguirre-Gamboa R, Li C, Mooiweer J, Ricaño-Ponce I, Borek Z, Koning F, Kooy-Winkelaar Y, Sollid LM, Qiao SW, Kumar V, Li Y, Franke L, Withoff S, Wijmenga C, Sanna S, Jonkers I; BIOS Consortium. van der Graaf A, et al. Front Genet. 2021 Jan 25;11:562434. doi: 10.3389/fgene.2020.562434. eCollection 2020. Front Genet. 2021. PMID: 33569077 Free PMC article.
Understanding human immune function using the resources from the Human Functional Genomics Project.
Netea MG, Joosten LA, Li Y, Kumar V, Oosting M, Smeekens S, Jaeger M, Ter Horst R, Schirmer M, Vlamakis H, Notebaart R, Pavelka N, Aguirre-Gamboa RR, Swertz MA, Tunjungputri RN, van de Heijden W, Franzosa EA, Ng A, Graham D, Lassen K, Schraa K, Netea-Maier R, Smit J, de Mast Q, van de Veerdonk F, Kullberg BJ, Tack C, van de Munckhof I, Rutten J, van der Graaf J, Franke L, Hofker M, Jonkers I, Platteel M, Maatman A, Fu J, Zhernakova A, van der Meer JW, Dinarello CA, van der Ven A, Huttenhouwer C, Koenen H, Joosten I, Xavier RJ, Wijmenga C. Netea MG, et al. Nat Med. 2016 Aug 4;22(8):831-3. doi: 10.1038/nm.4140. Nat Med. 2016. PMID: 27490433 No abstract available.
A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.
Li Y, Oosting M, Smeekens SP, Jaeger M, Aguirre-Gamboa R, Le KTT, Deelen P, Ricaño-Ponce I, Schoffelen T, Jansen AFM, Swertz MA, Withoff S, van de Vosse E, van Deuren M, van de Veerdonk F, Zhernakova A, van der Meer JWM, Xavier RJ, Franke L, Joosten LAB, Wijmenga C, Kumar V, Netea MG. Li Y, et al. Cell. 2016 Nov 3;167(4):1099-1110.e14. doi: 10.1016/j.cell.2016.10.017. Cell. 2016. PMID: 27814507 Free article.
Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits.
Aguirre-Gamboa R, Joosten I, Urbano PCM, van der Molen RG, van Rijssen E, van Cranenbroek B, Oosting M, Smeekens S, Jaeger M, Zorro M, Withoff S, van Herwaarden AE, Sweep FCGJ, Netea RT, Swertz MA, Franke L, Xavier RJ, Joosten LAB, Netea MG, Wijmenga C, Kumar V, Li Y, Koenen HJPM. Aguirre-Gamboa R, et al. Cell Rep. 2016 Nov 22;17(9):2474-2487. doi: 10.1016/j.celrep.2016.10.053. Epub 2016 Nov 3. Cell Rep. 2016. PMID: 27818087 Free PMC article.
Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study.
van Laarhoven A, Dian S, Aguirre-Gamboa R, Avila-Pacheco J, Ricaño-Ponce I, Ruesen C, Annisa J, Koeken VACM, Chaidir L, Li Y, Achmad TH, Joosten LAB, Notebaart RA, Ruslami R, Netea MG, Verbeek MM, Alisjahbana B, Kumar V, Clish CB, Ganiem AR, van Crevel R. van Laarhoven A, et al. Lancet Infect Dis. 2018 May;18(5):526-535. doi: 10.1016/S1473-3099(18)30053-7. Epub 2018 Feb 3. Lancet Infect Dis. 2018. PMID: 29395996
DNA methylation in childhood asthma: an epigenome-wide meta-analysis.
Xu CJ, Söderhäll C, Bustamante M, Baïz N, Gruzieva O, Gehring U, Mason D, Chatzi L, Basterrechea M, Llop S, Torrent M, Forastiere F, Fantini MP, Carlsen KCL, Haahtela T, Morin A, Kerkhof M, Merid SK, van Rijkom B, Jankipersadsing SA, Bonder MJ, Ballereau S, Vermeulen CJ, Aguirre-Gamboa R, de Jongste JC, Smit HA, Kumar A, Pershagen G, Guerra S, Garcia-Aymerich J, Greco D, Reinius L, McEachan RRC, Azad R, Hovland V, Mowinckel P, Alenius H, Fyhrquist N, Lemonnier N, Pellet J, Auffray C; BIOS Consortium; van der Vlies P, van Diemen CC, Li Y, Wijmenga C, Netea MG, Moffatt MF, Cookson WOCM, Anto JM, Bousquet J, Laatikainen T, Laprise C, Carlsen KH, Gori D, Porta D, Iñiguez C, Bilbao JR, Kogevinas M, Wright J, Brunekreef B, Kere J, Nawijn MC, Annesi-Maesano I, Sunyer J, Melén E, Koppelman GH. Xu CJ, et al. Lancet Respir Med. 2018 May;6(5):379-388. doi: 10.1016/S2213-2600(18)30052-3. Epub 2018 Feb 26. Lancet Respir Med. 2018. PMID: 29496485 Free article.
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses.
Bakker OB, Aguirre-Gamboa R, Sanna S, Oosting M, Smeekens SP, Jaeger M, Zorro M, Võsa U, Withoff S, Netea-Maier RT, Koenen HJPM, Joosten I, Xavier RJ, Franke L, Joosten LAB, Kumar V, Wijmenga C, Netea MG, Li Y. Bakker OB, et al. Nat Immunol. 2018 Jul;19(7):776-786. doi: 10.1038/s41590-018-0121-3. Epub 2018 May 21. Nat Immunol. 2018. PMID: 29784908 Free PMC article.
The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans.
Tunjungputri RN, Li Y, de Groot PG, Dinarello CA, Smeekens SP, Jaeger M, Doppenberg-Oosting M, Cruijsen M, Lemmers H, Toenhake-Dijkstra H, Aguirre-Gamboa R, Kumar V, Wijmenga C, Joosten LAB, Netea MG, van der Ven A, de Mast Q. Tunjungputri RN, et al. Thromb Haemost. 2018 Dec;118(12):2112-2125. doi: 10.1055/s-0038-1675603. Epub 2018 Nov 19. Thromb Haemost. 2018. PMID: 30453346
A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans.
Jaeger M, Matzaraki V, Aguirre-Gamboa R, Gresnigt MS, Chu X, Johnson MD, Oosting M, Smeekens SP, Withoff S, Jonkers I, Perfect JR, van de Veerdonk FL, Kullberg BJ, Joosten LAB, Li Y, Wijmenga C, Netea MG, Kumar V. Jaeger M, et al. J Infect Dis. 2019 Jul 31;220(5):862-872. doi: 10.1093/infdis/jiz206. J Infect Dis. 2019. PMID: 31241743 Free PMC article.
33 results