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Synergism by individual macronutrients explains the marked early GLP-1 and islet hormone responses to mixed meal challenge in mice.
Regul Pept. 2012 Oct 10;178(1-3):29-35. doi: 10.1016/j.regpep.2012.06.004. Epub 2012 Jun 28.
Regul Pept. 2012.
PMID: 22750278
Evidence for neural contribution to islet effects of DPP-4 inhibition in mice.
Ahlkvist L, Omar B, Pacini G, Ahrén B.
Ahlkvist L, et al.
Eur J Pharmacol. 2016 Jun 5;780:46-52. doi: 10.1016/j.ejphar.2016.03.030. Epub 2016 Mar 17.
Eur J Pharmacol. 2016.
PMID: 26997369
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Incretin hormone receptors are required for normal beta cell development and function in female mice.
Omar B, Ahlkvist L, Yamada Y, Seino Y, Ahrén B.
Omar B, et al. Among authors: ahlkvist l.
Peptides. 2016 May;79:58-65. doi: 10.1016/j.peptides.2016.03.012. Epub 2016 Mar 25.
Peptides. 2016.
PMID: 27020250
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Defective insulin secretion by chronic glucagon receptor activation in glucose intolerant mice.
Ahlkvist L, Omar B, Valeur A, Fosgerau K, Ahrén B.
Ahlkvist L, et al.
J Endocrinol. 2016 Mar;228(3):171-8. doi: 10.1530/JOE-15-0371. Epub 2015 Dec 23.
J Endocrinol. 2016.
PMID: 26698567
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Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion.
Ahlkvist L, Brown K, Ahrén B.
Ahlkvist L, et al.
Endocr Connect. 2013 Mar 18;2(2):69-78. doi: 10.1530/EC-12-0079. Print 2013 Jun 1.
Endocr Connect. 2013.
PMID: 23781322
Free PMC article.
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Time to Peak Glucose and Peak C-Peptide During the Progression to Type 1 Diabetes in the Diabetes Prevention Trial and TrialNet Cohorts.
Voss MG, Cuthbertson DD, Cleves MM, Xu P, Evans-Molina C, Palmer JP, Redondo MJ, Steck AK, Lundgren M, Larsson H, Moore WV, Atkinson MA, Sosenko JM, Ismail HM; DPT-1 and TrialNet Study Groups.
Voss MG, et al.
Diabetes Care. 2021 Oct;44(10):2329-2336. doi: 10.2337/dc21-0226. Epub 2021 Aug 6.
Diabetes Care. 2021.
PMID: 34362815
Free PMC article.
Clinical Trial.
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