Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2023 2
2024 11

Text availability

Article attribute

Article type

Publication date

Search Results

11 results

Results by year

Filters applied: . Clear all
Page 1
Molecular docking as a tool for the discovery of novel insight about the role of acid sphingomyelinase inhibitors in SARS- CoV-2 infectivity.
Alkafaas SS, Abdallah AM, Hassan MH, Hussien AM, Elkafas SS, Loutfy SA, Mikhail A, Murad OG, Elsalahaty MI, Hessien M, Elshazli RM, Alsaeed FA, Ahmed AE, Kamal HK, Hafez W, El-Saadony MT, El-Tarabily KA, Ghosh S. Alkafaas SS, et al. BMC Public Health. 2024 Feb 6;24(1):395. doi: 10.1186/s12889-024-17747-z. BMC Public Health. 2024. PMID: 38321448 Free PMC article. Review.
Acid sphingomyelinase (ASMase) is a lysosomal protein that catalyzes the conversion of sphingolipid (sphingomyelin) to ceramide. Ceramide molecules aggregate/assemble on the plasma membrane to form "platforms" that facilitate the viral intake into the cell. ...In silico mo …
Acid sphingomyelinase (ASMase) is a lysosomal protein that catalyzes the conversion of sphingolipid (sphingomyelin) to ceramide. Ceramide …
Recent Advances in Structural Optimization of Quinazoline-Based Protein Kinase Inhibitors for Cancer Therapy (2021-Present).
Abdel-Mohsen HT, Anwar MM, Ahmed NS, Abd El-Karim SS, Abdelwahed SH. Abdel-Mohsen HT, et al. Molecules. 2024 Feb 16;29(4):875. doi: 10.3390/molecules29040875. Molecules. 2024. PMID: 38398626 Free PMC article. Review.
A new class of chemotherapeutic agents known as quinazoline-based derivatives possessing anticancer properties consists of several well-known compounds that block different protein kinases and other molecular targets. This review highlights recent updates (2021-2024) on va …
A new class of chemotherapeutic agents known as quinazoline-based derivatives possessing anticancer properties consists of several well-know …
Synthesis and Characterization of Short α and β-Mixed Peptides with Excellent Anti-Lipase Activities.
Ahmed N, Asif S, Arfan M, Mahmood Q, Islam A, Gatasheh MK, Zia M. Ahmed N, et al. Molecules. 2024 Feb 7;29(4):765. doi: 10.3390/molecules29040765. Molecules. 2024. PMID: 38398517 Free PMC article.
The synthesized peptides with anti-lipase activity are N-Boc-beta-Pro-Gly-OBz (93%), N-Boc-O-Bz-Tyr-beta-Pro-beta-Pro-Gly-OBz (92%), N-Boc-O-Bz-Tyr-beta-Pro-COOH (91%), N-Boc-Phe-beta-Pro-OCH(3) (90%), and N-Boc-O-Bz-Tyr-beta-Pro-OCH(3) (89%). These peptides may function as lead …
The synthesized peptides with anti-lipase activity are N-Boc-beta-Pro-Gly-OBz (93%), N-Boc-O-Bz-Tyr-beta-Pro-beta-Pro-Gly-OBz (92%), N-Boc-O …
Repurposing of Strychnine as the Potential Inhibitors of Aldo-keto Reductase Family 1 Members B1 and B10: Computational Modeling and Pharmacokinetic Analysis.
Sarfraz M, Aziz M, Afzal S, Channar PA, Alsfouk BA, Kandhro GA, Hassan S, Sultan A, Hamad A, Arafat M, Qaiser MN, Ahmed A, Siddique F, Ejaz SA. Sarfraz M, et al. Protein J. 2024 Apr;43(2):207-224. doi: 10.1007/s10930-023-10163-z. Epub 2023 Nov 8. Protein J. 2024. PMID: 37940790
The obtained results fell within the expected range for drug molecules, confirming its suitability for further investigation. Additionally, density functional theory (DFT) studies were conducted to gain insight into the electronic properties contributing to the drug mol …
The obtained results fell within the expected range for drug molecules, confirming its suitability for further investigation. Additio …
Investigating the correlation between small molecular inhibitor utilization, peripheral blood monocytes, and treatment outcomes in Rosai Dorfman disease.
Reynolds SB, Wilcox S, Li Q, Ahmed AZ. Reynolds SB, et al. Ann Hematol. 2024 Jan;103(1):37-59. doi: 10.1007/s00277-023-05494-x. Epub 2023 Nov 9. Ann Hematol. 2024. PMID: 37940718
In evaluating outcomes, the proportion of partial responses was substantially higher in recipients of molecular as compared to conventional therapy (4/5 patients compared to 6/29) while complete responses were more common in the conventional therapy cohort (12/29 co …
In evaluating outcomes, the proportion of partial responses was substantially higher in recipients of molecular as compared to conventional …
11 results