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The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays.
Vinken M, Doktorova T, Ellinger-Ziegelbauer H, Ahr HJ, Lock E, Carmichael P, Roggen E, van Delft J, Kleinjans J, Castell J, Bort R, Donato T, Ryan M, Corvi R, Keun H, Ebbels T, Athersuch T, Sansone SA, Rocca-Serra P, Stierum R, Jennings P, Pfaller W, Gmuender H, Vanhaecke T, Rogiers V. Vinken M, et al. Among authors: ahr hj. Mutat Res. 2008 Sep-Oct;659(3):202-10. doi: 10.1016/j.mrrev.2008.04.006. Epub 2008 Apr 26. Mutat Res. 2008. PMID: 18514569 Review.
Meeting report: Validation of toxicogenomics-based test systems: ECVAM-ICCVAM/NICEATM considerations for regulatory use.
Corvi R, Ahr HJ, Albertini S, Blakey DH, Clerici L, Coecke S, Douglas GR, Gribaldo L, Groten JP, Haase B, Hamernik K, Hartung T, Inoue T, Indans I, Maurici D, Orphanides G, Rembges D, Sansone SA, Snape JR, Toda E, Tong W, van Delft JH, Weis B, Schechtman LM. Corvi R, et al. Among authors: ahr hj. Environ Health Perspect. 2006 Mar;114(3):420-9. doi: 10.1289/ehp.8247. Environ Health Perspect. 2006. PMID: 16507466 Free PMC article.
A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop.
Marx-Stoelting P, Adriaens E, Ahr HJ, Bremer S, Garthoff B, Gelbke HP, Piersma A, Pellizzer C, Reuter U, Rogiers V, Schenk B, Schwengberg S, Seiler A, Spielmann H, Steemans M, Stedman DB, Vanparys P, Vericat JA, Verwei M, van der Water F, Weimer M, Schwarz M. Marx-Stoelting P, et al. Among authors: ahr hj. Altern Lab Anim. 2009 Jul;37(3):313-28. doi: 10.1177/026119290903700314. Altern Lab Anim. 2009. PMID: 19678733 Review. No abstract available.
Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes.
Schug M, Stöber R, Heise T, Mielke H, Gundert-Remy U, Godoy P, Reif R, Blaszkewicz M, Ellinger-Ziegelbauer H, Ahr HJ, Selinski S, Günther G, Marchan R, Blaszkewicz M, Sachinidis A, Nüssler A, Oberemm A, Hengstler JG. Schug M, et al. Among authors: ahr hj. Arch Toxicol. 2013 Feb;87(2):337-45. doi: 10.1007/s00204-012-0999-8. Epub 2012 Dec 29. Arch Toxicol. 2013. PMID: 23274394
Barriers to validation: a report by the European Partnership fo Alternative Approaches to Animal Testing (EPAA) Working Group 5.
Ahr HJ, Alepée N, Breier S, Brekelmans C, Cotgreave I, Gribaldo L, Dal Negro G, De Silva O, Hartung T, Lacerda A, Leblanc B, Lecerf C, Linge JP, Louhimies S, Manou I, Maxwell G, Müller KK, Pape W, Redhead K, Schröder KR, Sladowski D, van der Jagt K, Vanparys P. Ahr HJ, et al. Altern Lab Anim. 2008 Sep;36(4):459-64. doi: 10.1177/026119290803600409. Altern Lab Anim. 2008. PMID: 18826335 No abstract available.
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