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Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant.
Tan YZ, Aiyer S, Mietzsch M, Hull JA, McKenna R, Grieger J, Samulski RJ, Baker TS, Agbandje-McKenna M, Lyumkis D. Tan YZ, et al. Among authors: aiyer s. Nat Commun. 2018 Sep 7;9(1):3628. doi: 10.1038/s41467-018-06076-6. Nat Commun. 2018. PMID: 30194371 Free PMC article.
B-to-A transition in target DNA during retroviral integration.
Jóźwik IK, Li W, Zhang DW, Wong D, Grawenhoff J, Ballandras-Colas A, Aiyer S, Cherepanov P, Engelman AN, Lyumkis D. Jóźwik IK, et al. Among authors: aiyer s. Nucleic Acids Res. 2022 Aug 26;50(15):8898-8918. doi: 10.1093/nar/gkac644. Nucleic Acids Res. 2022. PMID: 35947647 Free PMC article.
Overcoming Resolution Attenuation During Tilted Cryo-EM Data Collection.
Aiyer S, Baldwin PR, Tan SM, Shan Z, Oh J, Mehrani A, Bowman ME, Louie G, Passos DO, Đorđević-Marquardt S, Mietzsch M, Hull JA, Hoshika S, Barad BA, Grotjahn DA, McKenna R, Agbandje-McKenna M, Benner SA, Noel JAP, Wang D, Tan YZ, Lyumkis D. Aiyer S, et al. bioRxiv [Preprint]. 2023 Jul 15:2023.07.14.548955. doi: 10.1101/2023.07.14.548955. bioRxiv. 2023. PMID: 37503021 Free PMC article. Updated. Preprint.
Overcoming resolution attenuation during tilted cryo-EM data collection.
Aiyer S, Baldwin PR, Tan SM, Shan Z, Oh J, Mehrani A, Bowman ME, Louie G, Passos DO, Đorđević-Marquardt S, Mietzsch M, Hull JA, Hoshika S, Barad BA, Grotjahn DA, McKenna R, Agbandje-McKenna M, Benner SA, Noel JAP, Wang D, Tan YZ, Lyumkis D. Aiyer S, et al. Nat Commun. 2024 Jan 9;15(1):389. doi: 10.1038/s41467-023-44555-7. Nat Commun. 2024. PMID: 38195598 Free PMC article.
Assembly of the Bacterial Ribosome with Circularly Permuted rRNA.
Dong X, Sheng K, Gebert LFR, Aiyer S, MacRae IJ, Lyumkis D, Williamson JR. Dong X, et al. Among authors: aiyer s. bioRxiv [Preprint]. 2024 Apr 10:2024.04.10.588894. doi: 10.1101/2024.04.10.588894. bioRxiv. 2024. PMID: 38644992 Free PMC article. Preprint.
Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding.
Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Aiyer S, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D. Jing T, et al. Among authors: aiyer s. bioRxiv [Preprint]. 2024 Jan 27:2024.01.26.577436. doi: 10.1101/2024.01.26.577436. bioRxiv. 2024. PMID: 38328132 Free PMC article. Preprint.
Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model.
Loyola L, Achuthan V, Gilroy K, Borland G, Kilbey A, Mackay N, Bell M, Hay J, Aiyer S, Fingerman D, Villanueva RA, Cameron E, Kozak CA, Engelman AN, Neil J, Roth MJ. Loyola L, et al. Among authors: aiyer s. PLoS Pathog. 2019 Dec 9;15(12):e1008154. doi: 10.1371/journal.ppat.1008154. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31815961 Free PMC article.
89 results