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Repeated social defeat stress exacerbates lipopolysaccharide-induced behavioural deficits in mice: ameliorative role of Chrysophyllum albidum fruit extract through anti-neuroinflammation, antioxidant and neurochemical balance.
Ajayi AM, Ben-Azu B, Ogunkolade GE, Melete J, Oyedele AT, Umukoro S. Ajayi AM, et al. Metab Brain Dis. 2022 Oct;37(7):2467-2481. doi: 10.1007/s11011-022-01053-x. Epub 2022 Jul 22. Metab Brain Dis. 2022. PMID: 35867181
Pro-inflammatory cytokines (IL-1beta, IL-6 and TNF-alpha), dopamine, acetylcholinesterase, glutamic acid decarboxylase (GAD), malondialdehyde, nitrites, and reduced glutathione (GSH) were determined in brain tissue. CAFE significantly attenuated RSD and LPS-induced hypoloc …
Pro-inflammatory cytokines (IL-1beta, IL-6 and TNF-alpha), dopamine, acetylcholinesterase, glutamic acid decarboxylase (GAD), malondialdehyd …