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Characterization of a murine anti-laminin-1 monoclonal antibody (AK8) produced by immunization with mouse-derived laminin-1.
Kondo A, Inagaki J, Kobayashi K, Tsukamoto H, Yamamoto D, Nakatsuka M, Suzuki N, Nomizu M, Amano S, Matsubayashi H, Yasuda T, Lopez LR, Shoenfeld Y, Makino T, Matsuura E. Kondo A, et al. Clin Dev Immunol. 2005 Mar;12(1):67-73. doi: 10.1080/17402520400014168. Clin Dev Immunol. 2005. PMID: 15712601 Free PMC article.
Basement membranes of endometrium of pregnant mice and humans were immunostained with AK8 mAb. Thus, AK8 mAb recognized a common structure present in the G domain of the laminin-alpha1 chain in both mice and humans. The passive immunization of mice with AK8 m …
Basement membranes of endometrium of pregnant mice and humans were immunostained with AK8 mAb. Thus, AK8 mAb recognized a comm …
CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.
Dougherty GW, Mizuno K, Nöthe-Menchen T, Ikawa Y, Boldt K, Ta-Shma A, Aprea I, Minegishi K, Pang YP, Pennekamp P, Loges NT, Raidt J, Hjeij R, Wallmeier J, Mussaffi H, Perles Z, Elpeleg O, Rabert F, Shiratori H, Letteboer SJ, Horn N, Young S, Strünker T, Stumme F, Werner C, Olbrich H, Takaoka K, Ide T, Twan WK, Biebach L, Große-Onnebrink J, Klinkenbusch JA, Praveen K, Bracht DC, Höben IM, Junger K, Gützlaff J, Cindrić S, Aviram M, Kaiser T, Memari Y, Dzeja PP, Dworniczak B, Ueffing M, Roepman R, Bartscherer K, Katsanis N, Davis EE, Amirav I, Hamada H, Omran H. Dougherty GW, et al. Nat Commun. 2020 Nov 2;11(1):5520. doi: 10.1038/s41467-020-19113-0. Nat Commun. 2020. PMID: 33139725 Free PMC article.
CFAP45 binds AMP in vitro, consistent with structural modelling that identifies an AMP-binding interface between CFAP45 and AK8. Microtubule sliding of dyskinetic sperm from Cfap45(-/-) mice is rescued with the addition of either AMP or ADP with ATP, compared to ATP alone. …
CFAP45 binds AMP in vitro, consistent with structural modelling that identifies an AMP-binding interface between CFAP45 and AK8. Micr …
RNA-Dependent Cysteine Biosynthesis in Bacteria and Archaea.
Mukai T, Crnković A, Umehara T, Ivanova NN, Kyrpides NC, Söll D. Mukai T, et al. mBio. 2017 May 9;8(3):e00561-17. doi: 10.1128/mBio.00561-17. mBio. 2017. PMID: 28487430 Free PMC article.
The finding that the SepRS-SepCysS-SepCysE- and the selenocysteine-encoding systems are shared by the Euryarchaeota class I methanogens, the Crenarchaeota AK8/W8A-19 group, and an Asgard archaeon suggests that ancient archaea may have used both systems. ...
The finding that the SepRS-SepCysS-SepCysE- and the selenocysteine-encoding systems are shared by the Euryarchaeota class I methanogens, the …
The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes.
Panayiotou C, Solaroli N, Xu Y, Johansson M, Karlsson A. Panayiotou C, et al. Biochem J. 2011 Feb 1;433(3):527-34. doi: 10.1042/BJ20101443. Biochem J. 2011. PMID: 21080915
The full-length AK8, as well as its two domains AK8p1 and AK8p2, all showed similar AK enzyme activity. ...Expression of the proteins fused with green fluorescent protein demonstrated a cytosolic localization for both AK7 and AK8....
The full-length AK8, as well as its two domains AK8p1 and AK8p2, all showed similar AK enzyme activity. ...Expression of the proteins …
Next-generation sequencing, FISH mapping and synteny-based modeling reveal mechanisms of decreasing dysploidy in Cucumis.
Yang L, Koo DH, Li D, Zhang T, Jiang J, Luan F, Renner SS, Hénaff E, Sanseverino W, Garcia-Mas J, Casacuberta J, Senalik DA, Simon PW, Chen J, Weng Y. Yang L, et al. Plant J. 2014 Jan;77(1):16-30. doi: 10.1111/tpj.12355. Epub 2013 Dec 3. Plant J. 2014. PMID: 24127692 Free article.
The 12 inferred chromosomes (AK1-AK12) of an ancestor similar to melon and C. hystrix had strikingly different evolutionary fates, with cucumber chromosome C1 apparently resulting from insertion of chromosome AK12 into the centromeric region of translocated AK2/AK8, cucumb …
The 12 inferred chromosomes (AK1-AK12) of an ancestor similar to melon and C. hystrix had strikingly different evolutionary fates, with cucu …
Healthy Roots and Leaves: Comparative Genome Structure of Horseradish and Watercress.
Mandáková T, Lysak MA. Mandáková T, et al. Plant Physiol. 2019 Jan;179(1):66-73. doi: 10.1104/pp.18.01165. Epub 2018 Nov 5. Plant Physiol. 2019. PMID: 30397022 Free PMC article.
Our results show that horseradish and watercress genomes originated from a common ancestral (n = 8) genome, structurally resembling the Ancestral Crucifer Karyotype (n = 8), which, however, contained two unique translocation chromosomes (AK6/8 and AK8/6). Except for a 2.4- …
Our results show that horseradish and watercress genomes originated from a common ancestral (n = 8) genome, structurally resembling the Ance …
Co-expression Analysis of Genes and Tumor-Infiltrating Immune Cells in Metastatic Uterine Carcinosarcoma.
Huang R, Sun H, Yan G, Zhang L, Sun W, Zhang J, Yin H, Xian S, Hu P, Yan P, Zhu X, Meng T, Wang J, Huang Z. Huang R, et al. Reprod Sci. 2021 Sep;28(9):2685-2698. doi: 10.1007/s43032-021-00584-5. Epub 2021 Apr 27. Reprod Sci. 2021. PMID: 33905082
Combining gene co-expression and experimental validation results, we propose a potential mechanism of AK8, MPZ, and mast cells activated might play important parts in UCS metastasis....
Combining gene co-expression and experimental validation results, we propose a potential mechanism of AK8, MPZ, and mast cells activa …
Genetic Factors and Long-term Treatment-Related Neurocognitive Deficits, Anxiety, and Depression in Childhood Leukemia Survivors: An Exome-Wide Association Study.
Petrykey K, Lippé S, Sultan S, Robaey P, Drouin S, Affret-Bertout L, Beaulieu P, St-Onge P, Baedke JL, Yasui Y, Hudson MM, Laverdière C, Sinnett D, Krajinovic M. Petrykey K, et al. Cancer Epidemiol Biomarkers Prev. 2024 Feb 6;33(2):234-243. doi: 10.1158/1055-9965.EPI-23-0634. Cancer Epidemiol Biomarkers Prev. 2024. PMID: 38051303
RESULTS: Significant associations were identified in the entire discovery cohort (N = 229) between the AK8 gene and changes in neurocognitive function, whereas PTPRZ1, MUC16, TNRC6C-AS1 were associated with anxiety. ...
RESULTS: Significant associations were identified in the entire discovery cohort (N = 229) between the AK8 gene and changes in neuroc …
The story of promiscuous crucifers: origin and genome evolution of an invasive species, Cardamine occulta (Brassicaceae), and its relatives.
Mandáková T, Zozomová-Lihová J, Kudoh H, Zhao Y, Lysak MA, Marhold K. Mandáková T, et al. Ann Bot. 2019 Sep 24;124(2):209-220. doi: 10.1093/aob/mcz019. Ann Bot. 2019. PMID: 30868165 Free PMC article.
KEY RESULTS: All investigated species descended from a common ancestral Cardamine genome (n = 8), structurally resembling the Ancestral Crucifer Karyotype (n = 8), but differentiated by a translocation between chromosomes AK6 and AK8. Allotetraploid C. scutata originated b …
KEY RESULTS: All investigated species descended from a common ancestral Cardamine genome (n = 8), structurally resembling the Ancestral Cruc …
Adenine nucleotide metabolism and a role for AMP in modulating flagellar waveforms in mouse sperm.
Vadnais ML, Cao W, Aghajanian HK, Haig-Ladewig L, Lin AM, Al-Alao O, Gerton GL. Vadnais ML, et al. Biol Reprod. 2014 Jun;90(6):128. doi: 10.1095/biolreprod.113.114447. Epub 2014 Apr 16. Biol Reprod. 2014. PMID: 24740601 Free PMC article.
In addition to AK1 and AK2, which we previously demonstrated are present in outer dense fibers and mitochondrial sheath of the mouse sperm tail, we show that another AK, AK8, is present in a third flagellar compartment, the axoneme. These results extend the known regulator …
In addition to AK1 and AK2, which we previously demonstrated are present in outer dense fibers and mitochondrial sheath of the mouse sperm t …
17 results