Alamo L - Search Results

1

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.

Toepfer CN, Garfinkel AC, Venturini G, Wakimoto H, Repetti G, Alamo L, Sharma A, Agarwal R, Ewoldt JK, Cloonan P, Letendre J, Lun M, Olivotto I, Colan S, Ashley E, Jacoby D, Michels M, Redwood CS, Watkins HC, Day SM, Staples JF, Padrón R, Chopra A, Ho CY, Chen CS, Pereira AC, Seidman JG, Seidman CE. Toepfer CN, et al. Among authors: alamo l. Circulation. 2020 Mar 10;141(10):828-842. doi: 10.1161/CIRCULATIONAHA.119.042339. Epub 2020 Jan 27. Circulation. 2020. PMID: 31983222 Free PMC article.

2

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes.

Alamo L, Ware JS, Pinto A, Gillilan RE, Seidman JG, Seidman CE, Padrón R. Alamo L, et al. Elife. 2017 Jun 13;6:e24634. doi: 10.7554/eLife.24634. Elife. 2017. PMID: 28606303 Free PMC article.

3

The myosin interacting-heads motif is present in the relaxed thick filament of the striated muscle of scorpion.

Pinto A, Sánchez F, Alamo L, Padrón R. Pinto A, et al. Among authors: alamo l. J Struct Biol. 2012 Dec;180(3):469-78. doi: 10.1016/j.jsb.2012.08.010. Epub 2012 Sep 7. J Struct Biol. 2012. PMID: 22982253

4

Atomic model of a myosin filament in the relaxed state.

Woodhead JL, Zhao FQ, Craig R, Egelman EH, Alamo L, Padrón R. Woodhead JL, et al. Among authors: alamo l. Nature. 2005 Aug 25;436(7054):1195-9. doi: 10.1038/nature03920. Nature. 2005. PMID: 16121187

5

Three-dimensional reconstruction of tarantula myosin filaments suggests how phosphorylation may regulate myosin activity.

Alamo L, Wriggers W, Pinto A, Bártoli F, Salazar L, Zhao FQ, Craig R, Padrón R. Alamo L, et al. J Mol Biol. 2008 Dec 26;384(4):780-97. doi: 10.1016/j.jmb.2008.10.013. Epub 2008 Oct 14. J Mol Biol. 2008. PMID: 18951904 Free PMC article.

6

Sequential myosin phosphorylation activates tarantula thick filament via a disorder-order transition.

Espinoza-Fonseca LM, Alamo L, Pinto A, Thomas DD, Padrón R. Espinoza-Fonseca LM, et al. Among authors: alamo l. Mol Biosyst. 2015 Aug;11(8):2167-79. doi: 10.1039/c5mb00162e. Mol Biosyst. 2015. PMID: 26038232 Free PMC article.

7

Tarantula myosin free head regulatory light chain phosphorylation stiffens N-terminal extension, releasing it and blocking its docking back.

Alamo L, Li XE, Espinoza-Fonseca LM, Pinto A, Thomas DD, Lehman W, Padrón R. Alamo L, et al. Mol Biosyst. 2015 Aug;11(8):2180-9. doi: 10.1039/c5mb00163c. Mol Biosyst. 2015. PMID: 26038302 Free PMC article.

8

Structure of the myosin filaments of relaxed and rigor vertebrate striated muscle studied by rapid freezing electron microscopy.

Craig R, Alamo L, Padrón R. Craig R, et al. Among authors: alamo l. J Mol Biol. 1992 Nov 20;228(2):474-87. doi: 10.1016/0022-2836(92)90836-9. J Mol Biol. 1992. PMID: 1453458

9

Direct determination of myosin filament symmetry in scallop striated adductor muscle by rapid freezing and freeze substitution.

Craig R, Padrón R, Alamo L. Craig R, et al. Among authors: alamo l. J Mol Biol. 1991 Jul 5;220(1):125-32. doi: 10.1016/0022-2836(91)90386-k. J Mol Biol. 1991. PMID: 2067011

10

Towards an atomic model of the thick filaments of muscle.

Padrón R, Alamo L, Murgich J, Craig R. Padrón R, et al. Among authors: alamo l. J Mol Biol. 1998 Jan 9;275(1):35-41. doi: 10.1006/jmbi.1997.1448. J Mol Biol. 1998. PMID: 9451437 Review.

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