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Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia.
Chang Y, Min J, Jarusiewicz JA, Actis M, Yu-Chen Bradford S, Mayasundari A, Yang L, Chepyala D, Alcock LJ, Roberts KG, Nithianantham S, Maxwell D, Rowland L, Larsen R, Seth A, Goto H, Imamura T, Akahane K, Hansen BS, Pruett-Miller SM, Paietta EM, Litzow MR, Qu C, Yang JJ, Fischer M, Rankovic Z, Mullighan CG. Chang Y, et al. Among authors: alcock lj. Blood. 2021 Dec 9;138(23):2313-2326. doi: 10.1182/blood.2020006846. Blood. 2021. PMID: 34110416 Free PMC article.
Development of Potent and Selective Janus Kinase 2/3 Directing PG-PROTACs.
Alcock LJ, Chang Y, Jarusiewicz JA, Actis M, Nithianantham S, Mayasundari A, Min J, Maxwell D, Hunt J, Smart B, Yang JJ, Nishiguchi G, Fischer M, Mullighan CG, Rankovic Z. Alcock LJ, et al. ACS Med Chem Lett. 2022 Feb 21;13(3):475-482. doi: 10.1021/acsmedchemlett.1c00650. eCollection 2022 Mar 10. ACS Med Chem Lett. 2022. PMID: 35300081 Free PMC article.
Chemical methods for mapping cysteine oxidation.
Alcock LJ, Perkins MV, Chalker JM. Alcock LJ, et al. Chem Soc Rev. 2018 Jan 2;47(1):231-268. doi: 10.1039/c7cs00607a. Chem Soc Rev. 2018. PMID: 29242887 Review.