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Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2.
Das Gupta K, Shakespear MR, Curson JEB, Murthy AMV, Iyer A, Hodson MP, Ramnath D, Tillu VA, von Pein JB, Reid RC, Tunny K, Hohenhaus DM, Moradi SV, Kelly GM, Kobayashi T, Gunter JH, Stevenson AJ, Xu W, Luo L, Jones A, Johnston WA, Blumenthal A, Alexandrov K, Collins BM, Stow JL, Fairlie DP, Sweet MJ. Das Gupta K, et al. Among authors: alexandrov k. Cell Rep. 2020 Feb 25;30(8):2712-2728.e8. doi: 10.1016/j.celrep.2020.02.007. Cell Rep. 2020. PMID: 32101747 Free article.
Leishmania cell-free protein expression system.
Kovtun O, Mureev S, Jung W, Kubala MH, Johnston W, Alexandrov K. Kovtun O, et al. Among authors: alexandrov k. Methods. 2011 Sep;55(1):58-64. doi: 10.1016/j.ymeth.2011.06.006. Epub 2011 Jun 16. Methods. 2011. PMID: 21704167
Quantitative analysis of prenylated RhoA interaction with its chaperone, RhoGDI.
Tnimov Z, Guo Z, Gambin Y, Nguyen UT, Wu YW, Abankwa D, Stigter A, Collins BM, Waldmann H, Goody RS, Alexandrov K. Tnimov Z, et al. Among authors: alexandrov k. J Biol Chem. 2012 Aug 3;287(32):26549-62. doi: 10.1074/jbc.M112.371294. Epub 2012 May 24. J Biol Chem. 2012. PMID: 22628549 Free PMC article.
Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae.
Gambin Y, Ariotti N, McMahon KA, Bastiani M, Sierecki E, Kovtun O, Polinkovsky ME, Magenau A, Jung W, Okano S, Zhou Y, Leneva N, Mureev S, Johnston W, Gaus K, Hancock JF, Collins BM, Alexandrov K, Parton RG. Gambin Y, et al. Among authors: alexandrov k. Elife. 2013 Jan 1;3:e01434. doi: 10.7554/eLife.01434. Elife. 2013. PMID: 24473072 Free PMC article.
Mechanism of activation of protein kinase JAK2 by the growth hormone receptor.
Brooks AJ, Dai W, O'Mara ML, Abankwa D, Chhabra Y, Pelekanos RA, Gardon O, Tunny KA, Blucher KM, Morton CJ, Parker MW, Sierecki E, Gambin Y, Gomez GA, Alexandrov K, Wilson IA, Doxastakis M, Mark AE, Waters MJ. Brooks AJ, et al. Among authors: alexandrov k. Science. 2014 May 16;344(6185):1249783. doi: 10.1126/science.1249783. Science. 2014. PMID: 24833397
Rapid mapping of interactions between Human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy.
Sierecki E, Stevers LM, Giles N, Polinkovsky ME, Moustaqil M, Mureev S, Johnston WA, Dahmer-Heath M, Skalamera D, Gonda TJ, Gabrielli B, Collins BM, Alexandrov K, Gambin Y. Sierecki E, et al. Among authors: alexandrov k. Mol Cell Proteomics. 2014 Sep;13(9):2233-45. doi: 10.1074/mcp.M113.037275. Epub 2014 May 27. Mol Cell Proteomics. 2014. PMID: 24866125 Free PMC article.
225 results